| ¿µ¹® | multiple myeloma | ÇÑ±Û | ´Ù¹ß°ñ¼öÁ¾ |
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| ¿µ¹® | white blood cell(WBC), leukocyte | ÇÑ±Û | ¹éÇ÷±¸ |
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| ¿µ¹® | mast cell | ÇÑ±Û | ºñ¸¸ ¼¼Æ÷ |
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| GCT | general care and treatment; germ-cell tumor; giant cell thyroiditis; giant cell tumor |
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| JVP | [POMD P 49 - 52] 1) Jugular Vein Pressure 2) Jugular Venous Pulse ... |
| MC | mass casualties; mast cell; Master of Surgery [Lat. Magister Chirurgiae]; maximum concentration; Med... |
| GPC | gastric parietal cell; gel permeation chromatography; giant papillary conjunctivitis; glycophorin C;... |
| RGC | radio-gas chromatography; remnant gastric cancer; retinal ganglion cell; right giant cell |
| HMCL | human myeloma cell line |
|---|---|
| M.M. | Multiple Myeloma |
| MM | Myeloma |
| SMM | Smoldering multiple myeloma |
| CGC | cerebral giant cell |
| giant cell myeloma | A bone tumour composed of cellular spindle-cell stroma containing scattered multinucleated giant cells resembling osteoclasts. The tumours range from benign to frankly malignant lesions. The tumour occurs most frequently in an end of a long tubular bone in young adults. (12 Dec 1998) |
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| plasma cell myeloma | Cells resemble mature or immature plasma cells with nuclei that appear cleaved or resemble immunoblasts. The tumour cells are CD19- , CD20- , CD22- and SIg- , but are also cIg+ and CD38+. The Ig heavy and light chain genes can be translocated or deleted. These neoplasms are often disseminated BM tumours of adults and progress to multiple myeloma. (05 Mar 2000) |
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| myeloma cell | <haematology, oncology> Neoplastic plasma cell. The proliferating plasma cells often replace all the others within the marrow, leading to immune deficiency and frequently there is destruction of the bone cortex. Because they are monoclonal in origin they secrete a monoclonal immunoglobulin. Bence Jones proteins are monoclonal immunoglobulin light chains overproduced by myeloma cells and excreted in the urine. Myeloma cell lines are used for producing hybridomas in raising monoclonal antibodies. (18 Nov 1997) |
| amyloidosis of multiple myeloma | Foci of amyloidosis in mesenchymal tissues of some persons with multiple myeloma; no direct relation between amyloid and Bence Jones protein is conclusively known. (05 Mar 2000) |
| cancer, multiple myeloma | A bone marrow cancer involving a type of white blood cell called a plasma (or myeloma) cell. The tumour cells can form a single collection (a plasmacytoma) or many tumours (multiple myeloma). Plasma cells are part of the immune system and make antibodies. Because patients have an excess of identical plasma cells, they have too much of one type of antibody. As myeloma cells increase in number, they damage and weaken the bones, causing pain and often fractures. When bones are damaged, calcium is released into the blood leading to hypercalcaemia (excess calcium in the blood) and that causes loss of appetite, nausea, thirst, fatigue, muscle weakness, restlessness, and confusion. Myeloma cells prevent the bone marrow from forming normal plasma cells and other white blood cells important to the immune system so patients may not be able to fight infections. The cancer cells can also prevent the growth of new red blood cells, causing anaemia. Excess antibody proteins and calcium may prevent the kidneys from filtering and cleaning the blood properly Cancer, non-Hodgkin's lymphoma: A lymphoma is a cancer that develops in the lymphatic system. The most common symptom of non-Hodgkin's lymphomas is a painless swelling in the lymph nodes in the neck, underarm, or groin. Non-Hodgkin's lymphomas are diagnosed with a biopsy of an enlarged lymph node. Follow-up examinations are important after lymphoma treatment. Most relapses occur in the first 2 years after therapy. (12 Dec 1998) |
| cancer, myeloma | A bone marrow cancer involving a type of white blood cell called a plasma (or myeloma) cell. The tumour cells can form a single collection (a plasmacytoma) or many tumours (multiple myeloma). Plasma cells are part of the immune system and make antibodies. Because patients have an excess of identical plasma cells, they have too much of one type of antibody. As myeloma cells increase in number, they damage and weaken the bones, causing pain and often fractures. When bones are damaged, calcium is released into the blood leading to hypercalcaemia (too much calcium in the blood) and that causes loss of appetite, nausea, thirst, fatigue, muscle weakness, restlessness, and confusion. Myeloma cells prevent the bone marrow from forming normal plasma cells and other white blood cells important to the immune system so patients may not be able to fight infections. The cancer cells can also prevent the growth of new red blood cells, causing anaemia. Excess antibody proteins and calcium may prevent the kidneys from filtering and cleaning the blood properly. (12 Dec 1998) |
| multiple myeloma | <oncology, tumour> See myeloma cell. (18 Nov 1997) |
| myeloma | <oncology, tumour> A malignant tumour composed of plasma cells of the type normally found in the bone marrow. (18 Nov 1997) |
| myeloma protein | <haematology, oncology> The immunoglobulins and Bence Jones proteins secreted by myeloma cells. (18 Nov 1997) |
| endothelial myeloma | A malignant primary bone tumour that arises most commonly in the first three decades of life. It is highly malignant (prone to spread) and often requires treatment with some combination of radiation therapy and chemotherapy. (27 Sep 1997) |
| L-chain myeloma | bence Jones myeloma |
| carcinoma, giant cell | An epithelial neoplasm characterised by unusually large anaplastic cells. It is highly malignant with fulminant clinical course, bizarre histologic appearance and poor prognosis. It is most common in the lung and thyroid. (12 Dec 1998) |
| malignant giant cell tumour | A type of bone tumour. (12 Dec 1998) |
| giant cell | <pathology> A cell of large size, often with many nuclei. They are multinucleated masses produced by the fusion of many cells. They are often associated with viral infections. In AIDS, they are induced when the envelope glycoprotein of HIV binds to the CD4 antigen of uninfected neighboring T4 cells. The resulting syncytium leads to cell death and thus may account for the cytopathic effect of the virus. (18 Jul 2002) |
| giant cell aortitis | <pathology> Giant cell arteritis involving the aorta. (05 Mar 2000) |
| giant cell arteritis | <pathology> An inflammatory condition of the temporal artery. It is a serious chronic vascular disease, characterised by inflammation of the walls of the blood vessels (vasculitis). The age of affected patients is usually over 50 years of age. It most often involves the carotid artery system, and can lead to blindness or stroke. It can be diagnosed by biopsy of an artery, but there is often a false negative result. Elevation of the erythrocyte sedimentation rate is typical. Treatment is with high dose steroids. Common symptoms include headaches and tenderness over the temple (temporal artery). Can be associated with polymyalgia rheumatica. See: polymyalgia rheumatica. Synonym: cranial arteritis, temporal arteritis (20 Jun 2000) |
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