| 영문 | mutation | 한글 | 돌연변이 |
|---|---|---|---|
| 설명 | 세포의 dna 자체의 변이에 의해 일어나는 세포변이를 말한다. 이러한 경우 돌연변이로 일어난 세포는 그 이후 딸세포(daughter cell)에서도 그 변이가 여전히 유지되므로 종(species)의 변화나, 혹은 세포의 악성변환(malignant transformation)에 관여한다. |
||
| GAWTS | genomic amplification with transcript sequencing |
|---|---|
| gDNA | genomic deoxyribonucleic acid |
| ARMS | adverse reaction monitoring system; amplification refractory mutation system |
| MF | magnetic field; meat free; medium frequency; megafarad; membrane filler; merthiolate-formaldehyde [s... |
| TFM | testicular feminization male; testicular feminization mutation; total fluid movement; transmission e... |
| CGH | Comparative Genomic Hybridisation |
|---|---|
| gDNA | Genomic DNA |
| GISH | Genomic in situ hybridization |
| RLGS | Restriction Landmark Genomic Scanning |
| ARMS | Amplification Refractory Mutation System |
| genomic | Relating to a genome. (05 Mar 2000) |
|---|---|
| genomic DNA | <molecular biology> The DNA which is found in the organisms genome and is passed on to offspring as information necessary for survival. The phrase is used to distinguish between other types of DNA, such as found within plasmids. (09 Oct 1997) |
| genomic formula | <molecular biology> The method used to identify the number of sets of chromosomes within a cell or organism (i.e. Its ploidy). Each set is designated n so one set is n is haploid, two sets is 2n is diploid, three sets is 3n is triploid, four sets is 4n is tetraploid, etc. Also, 2n+1 is known as trisomy (i.e. Two full sets plus a third copy of one of the chromosomes). (09 Oct 1997) |
| genomic imprinting | <genetics, molecular biology> Parent specific expression or repression of genes or chromosomes in offspring. There are an increasing number of recognised chromosomal imprinting events in pathological conditions: for example preferential transmission of paternal or maternal predisposition to diabetes or atopy, preferential retention of paternal alleles in rhabdomyosarcoma, osteosarcoma, retinoblastoma and Wilm's tumour, preferential translocation to the paternal chromosome 9 of a portion of maternal chromosome 22 to form the Philadelphia chromosome of chronic myeloid leukaemia. (18 Nov 1997) |
| genomic library | <molecular biology> A collection of DNA molecules, derived from restriction fragments that have been cloned in vectors, that includes all or part of the genetic material of an organism. (18 Nov 1997) |
| library, genomic | A collection of DNA clones made from a set of randomly generated overlapping DNA fragments representing the entire genome of an organism. As a molecular genetic sequel to john steinbeck's of mice and men , today you can have a mouse genomic library or a human genomic library. (12 Dec 1998) |
| acquired mutation | A change in a gene or chromosome that occurs in a single cell after the conception of the individual. That change is then passed along to all cells descended from that cell. Acquired mutations are involved in the development of cancer. (12 Dec 1998) |
| addition-deletion mutation | <molecular biology> A type of mutation that results from insertion or deletion of a single nucleotide into, or from, an open reading frame in the normal DNA sequence. Normally, the genetic code is read in the wrong frame, three nucleotides at a time, and the entire sequence downstream of the mutation, is translated into a polypeptide with a garbled amino acid sequence from the mutated codon onwards. These mutations may be induced by certain types of mutagens or may occur spontaneously and usually result in the generation, downstream, of nonsense, chain termination codons. Synonym: addition mutation, addition-deletion mutation, deletion mutation, reading-frameshift mutation. (21 Jun 2000) |
| addition mutation | <molecular biology> A type of mutation that results from insertion or deletion of a single nucleotide into, or from, an open reading frame in the normal DNA sequence. Normally, the genetic code is read in the wrong frame, three nucleotides at a time, and the entire sequence downstream of the mutation, is translated into a polypeptide with a garbled amino acid sequence from the mutated codon onwards. These mutations may be induced by certain types of mutagens or may occur spontaneously and usually result in the generation, downstream, of nonsense, chain termination codons. Synonym: addition mutation, addition-deletion mutation, deletion mutation, reading-frameshift mutation. (21 Jun 2000) |
| amber mutation | <molecular biology> A mutation from a codon which codes for an amino acid into the amber codon UAG, which normally signals that the translation of mRNA into an amino acid chain should stop. The mutation causes the amino acid chain to stop forming before it is actually completed. (09 Oct 1997) |
| back mutation | <molecular biology> A mutation that causes a mutant gene to revert to its original wild-type base sequence. Compare: forward mutation. (09 Oct 1997) |
| reading-frameshift mutation | <molecular biology> A type of mutation that results from insertion or deletion of a single nucleotide into, or from, an open reading frame in the normal DNA sequence. Normally, the genetic code is read in the wrong frame, three nucleotides at a time, and the entire sequence downstream of the mutation, is translated into a polypeptide with a garbled amino acid sequence from the mutated codon onwards. These mutations may be induced by certain types of mutagens or may occur spontaneously and usually result in the generation, downstream, of nonsense, chain termination codons. Synonym: addition mutation, addition-deletion mutation, deletion mutation, reading-frameshift mutation. (21 Jun 2000) |
| germinal mutation | A mutation in the germ cells (the cells which will undergo meiosis to form the gametes). Such mutations are therefore passed on to offspring. (09 Oct 1997) |
| germ-line mutation | Any detectable and heritable alteration in the lineage of germ cells. Mutations in these cells (i.e., "generative" cells ancestral to the gametes) are transmitted to progeny while those in somatic cells are not. (12 Dec 1998) |
| reverse mutation | <molecular biology> A mutation that causes a mutant gene to revert to its original wild-type base sequence. Compare: forward mutation. (09 Oct 1997) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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