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GAWTS genomic amplification with transcript sequencing
gDNA genomic deoxyribonucleic acid
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LOI Loss of imprinting
IC imprinting center
CGH Comparative Genomic Hybridisation
gDNA Genomic DNA
GISH Genomic in situ hybridization
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CancerWEB ¿µ¿µ ÀÇÇлçÀü ¸ÂÃã °Ë»ö °á°ú : 1 ÆäÀÌÁö: 1
genomic imprinting <genetics, molecular biology> Parent specific expression or repression of genes or chromosomes in offspring. There are an increasing number of recognised chromosomal imprinting events in pathological conditions: for example preferential transmission of paternal or maternal predisposition to diabetes or atopy, preferential retention of paternal alleles in rhabdomyosarcoma, osteosarcoma, retinoblastoma and Wilm's tumour, preferential translocation to the paternal chromosome 9 of a portion of maternal chromosome 22 to form the Philadelphia chromosome of chronic myeloid leukaemia.
(18 Nov 1997)
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imprinting 1. <genetics> A remarkable genetic phenomenon. The gist is that gene expression depends on the sex of the transmitting parent. There is, for example, increased severity of neurofibromatosis when the gene for it came from the mother.
2. <psychology> A particular kind of learning characterised by occurrence in very early life, rapidity of acquisition, and relative insusceptibility to forgetting or extinction. Imprinted behaviour includes most (or all) behaviour commonly called instinctive, but imprinting is used purely descriptively.
(04 Jul 1999)
genomic Relating to a genome.
(05 Mar 2000)
genomic DNA <molecular biology> The DNA which is found in the organisms genome and is passed on to offspring as information necessary for survival. The phrase is used to distinguish between other types of DNA, such as found within plasmids.
(09 Oct 1997)
genomic formula <molecular biology> The method used to identify the number of sets of chromosomes within a cell or organism (i.e. Its ploidy). Each set is designated n so one set is n is haploid, two sets is 2n is diploid, three sets is 3n is triploid, four sets is 4n is tetraploid, etc. Also, 2n+1 is known as trisomy (i.e. Two full sets plus a third copy of one of the chromosomes).
(09 Oct 1997)
genomic library <molecular biology> A collection of DNA molecules, derived from restriction fragments that have been cloned in vectors, that includes all or part of the genetic material of an organism.
(18 Nov 1997)
library, genomic A collection of DNA clones made from a set of randomly generated overlapping DNA fragments representing the entire genome of an organism. As a molecular genetic sequel to john steinbeck's of mice and men , today you can have a mouse genomic library or a human genomic library.
(12 Dec 1998)
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  • Genomic Imprinting - »õâ The variable phenotypic expression of a GENE depending on whether it is of paternal or maternal origin, which is a function of the DNA METHYLATION pattern. Imprinted regions are observed to be more methylated and less transcriptionally active. (Segen, Dictionary of Modern Medicine, 1992)
    Synonyms : Imprinting, Genetic, Imprinting, Genomic, Imprinting, Parental
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genomic imprinting An epigenetic modification in the expression of a gene or genes which varies in its effect depending on whether the active allele is inherited from the mother or the father.
Ãâó: www.stjude.org/glossary
genomic imprinting Phenomenon in which the expression of certain genes is determined by whether the gene is inherited from the female or male parent.
Ãâó: www.modernhumanorigins.com/g.html
genomic imprinting methylation and penetrance are other factors that may influence the expression of characters. If one of the possible genotypes is an embryonic lethal, the observed proportions would be different from expected ones (also remember the cytoplasmic male sterility in plants).
Ãâó: dorakmt.tripod.com/genetics/notes02.html
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