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| ¼³¸í | 1. ³¹³¹ÀÇ »ý¹°Ã¼¿¡ µé¾îÀÖ´Â À¯ÀüÁ¤º¸ Àüü¸¦ À̸£´Â ¸». ÁøÇÙ¼¼Æ÷¿¡¼´Â ¿°»öü ½Ö³»¿¡, ¼¼±Õ¿¡¼´Â ´ÜÀÏ¿°»öü¿¡, ¶Ç ¹ÙÀÌ·¯½º¿¡¼´Â DNA³ª RNA ³»¿¡ ÇÔÀ¯µÇ¾î ÀÖ´Ù. 1920³â H. À®Å¬·¯´Â ´Ü¹èüÀÇ ¿°»öü ÇÑ ½ÖÀ» °Ô³ðÀ̶õ ¿ë¾î·Î »ç¿ëÇϱ⸦ Á¦Ã¢Çß´Ù. À¯ÀüÀÚ(gene)¿Í ¿°»öü(chromosome) µÎ ´Ü¾î¸¦ ÇÕ¼ºÇÑ °ÍÀÌ genomeÀ¸·Î ¿ì¸®¸»·Î´Â À¯Àüü·Î Ç¥ÁØÈµÇ¾ú´Ù. 1À¯Àüü ¼Ó¿¡´Â »óµ¿¿°»öü°¡ Æ÷Ç﵃ ¼ö ¾øÀ¸¸ç, À¯Àüü ¼ÓÀÇ ÇѰ³ÀÇ ¿°»öü ¶Ç´Â ±× ÀϺκи¸ »ó½ÇµÇ¾îµµ »ýȰ±â´É¿¡ Áß´ëÇÑ ¿µÇâÀ» ¹Þ´Â´Ù. À¯Àüü¸¦ ±¸¼ºÇÏ´Â ¿°»öü´Â °¢Á¾ »ý¹°¿¡ ÀÖ¾î¼ °íÀ¯ÀÇ ±âº»¼ö·Î ÀÌ·ç¾îÁ® ÀÖ´Ù. ÀÌ¿Í °°ÀÌ À¯Àüü°¡ ¿©·¯ °³ÀÇ ÀåÀ¸·Î ±¸¼ºµÈ ±³°ú¼¶ó°í ÇÑ´Ù¸é ¿°»öü´Â °³°³ÀÇ ÀåÀ̶ó ÇÒ ¼ö ÀÖ°í, À¯ÀüÀÚ´Â ÀåÀ» ±¸¼ºÇÏ´Â ¹®ÀåÀ̶ó ÇÒ °ÍÀ̸ç, ´Ù½Ã ¹®ÀåÀ» ±¸¼ºÇÏ´Â ±ÛÀÚ ÇϳªÇϳª°¡ ¿°±â½ÖÀ̶ó°í ÇÒ ¼ö ÀÖ´Ù. 2. ÇÑ °³Ã¼¿¡ ÀÖ´Â À¯ÀüÀÚÀÇ ¿ÏÀüÇÑ ¼¼Æ®. |
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| CA | anterior commissure [Lat. commissura anterior]; calcium antagonist; California [rabbit]; cancer; Can... |
|---|---|
| cRNA | chromosomal ribonucleic acid |
| ICBR | increased chromosomal breakage rate |
| NHC | National Health Council; neighborhood health center; neonatal hypocalcemia; nonhistone chromosomal [... |
| NHCP | nonhistone chromosomal protein |
| CGH | Comparative genome hybridization |
|---|---|
| GGR | Global Genome Repair |
| HGP | Human Genome Project |
| MGD | Mouse Genome Database |
| CA | Chromosomal aberration |
| genome, chromosomal | All of the genetic information in the chromosomes of an organism. For humans, that is all of the DNA contained in our normal complement of 46 rod-like chromosomes in virtually every cell in the body. (Mature red blood cells, for one exception, have no nucleus and therefore no chromosomes). The chromosomal genome is synonymous with the nuclear genome. Together with the mitochondrial genome, it constitutes the genome of the human being. (12 Dec 1998) |
|---|
| chromosomal | Pertaining to chromosomes. (18 Nov 1997) |
|---|---|
| chromosomal aberration | Any abnormality of a chromosome's number or structure. (09 Oct 1997) |
| chromosomal deletion | A microscopically evident loss of part of a chromosome. See: monosomy. (05 Mar 2000) |
| chromosomal gap | A localised area of thinning in a chromatid which may simulate a complete break. (05 Mar 2000) |
| chromosomal instability syndromes | A group of mendelian conditions associated with chromosomal instability and breakage in vitro, they often manifest an increased tendency to certain types of malignancies. See: Bloom's syndrome, fragile X syndrome, xeroderma pigmentosum. (05 Mar 2000) |
| chromosomal map | A formal, stylised representation of the karyotype and of the positioning and ordering on it of those loci that have been localised by any of several mapping methods. (05 Mar 2000) |
| chromosomal mutation | Can refer to any of a number of DNA mutations which results in a change in the protein encoded by the mutated gene, such as point mutations, insertion or deletion mutations (frameshift mutations), or nonsense mutations. More often this refers to mutations involving chromosomes, such as the inversion of part of one chromosome such that the inverted part no longer matches with its homologous pair, a translocation of one part of a chromosome to a different chromosome, deletions of parts of chromosomes, or accidents which happen during the division of the nucleus like the unequal portioning of chromosomes between the daughter cells. (09 Oct 1997) |
| chromosomal proteins, non-histone | Nucleoproteins which in contrast to histones are acid insoluble. They are involved in chromosomal functions; e.g. They bind selectively to DNA, stimulate transcription resulting in tissue-specific RNA synthesis and undergo specific changes in response to various hormones or phytomitogens. (12 Dec 1998) |
| chromosomal region | That part of a chromosome defined either by anatomical details, notably banding, or by its linkages (linkage group). (05 Mar 2000) |
| chromosomal RNA | RNA associated with the chromosome (not mRNA, tRNA, or rRNA) that may have a role in transcription. (05 Mar 2000) |
| chromosomal syndrome | <syndrome> General designation for syndrome's due to chromosomal aberrations; typically associated with mental retardation and multiple congenital anomalies. (05 Mar 2000) |
| chromosomal trait | A trait dependent on a recurrent chromosomal aberration. (05 Mar 2000) |
| nonhistone chromosomal protein | <molecular biology> Chromatin consists of DNA, histones and a very heterogeneous group of other proteins, that include DNA polymerases, regulator proteins, etc. They are often lumped together terminologically as nonhistone proteins or acidic proteins, to distinguish them from the basic histones. (18 Nov 1997) |
| genome | <genetics, molecular biology> The total set of genes carried by an individual or cell. (18 Nov 1997) |
| genome, bacterial | The complete gene complement contained in a single chromosome in a bacterium. (12 Dec 1998) |
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