| ¿µ¹® | genetic engineering | ÇÑ±Û | À¯Àü°øÇÐ |
|---|---|---|---|
| ¼³¸í | 1. À¯ÀüÀÚÀÇ ÇÕ¼ºÀ̳ª º¯Çü µûÀ§¸¦ ¿¬±¸ÇÏ´Â Çй®. ÀÀ¿ë À¯ÀüÇÐÀÇ ÇÑ ºÐ¾ß·Î, º´ÀÇ Ä¡·á³ª ÀÌ·Î¿î »ê¹°ÀÇ ´ë·® »ý»êÀ» ¸ñÀûÀ¸·Î ÇÑ´Ù. 2. »ý¹°ÀÇ À¯ÀüÀÚ¸¦ ÀΰøÀûÀ¸·Î °¡°øÇÏ¿© Àΰ£¿¡°Ô ÇÊ¿äÇÑ ¹°ÁúÀ» ´ë·®À¸·Î °ª½Î°Ô ¾ò´Â ±â¼ú. 1970³â´ë¿¡ µé¾î¼¸é¼ °æÀÌÀûÀÎ °úÇбâ¼úÀÇ Çϳª·Î Å« ÁÖ¸ñÀ» ²ø°í ÀÖÀ¸¸ç, ÀÌ ºÐ¾ß¿¡´Â ÀçÁ¶ÇÕ DNA±â¼ú-¼¼Æ÷À¶ÇÕ±â¼ú ¹× ÇÙġȯ±â¼ú µîÀÌ ÀÖ´Ù. ÀçÁ¶ÇÕ DNA ±â¼ú¿¡ ÀÇÇÏ¿© ÀΰøÀûÀ¸·Î ÀçÁ¶ÇÕÀ¯ÀüÀÚ¸¦ ¸¸µç ÃÖÃÊÀÇ º¸°í´Â 1972³â Àè½¼ µîÀÌ ÇÏ¿´°í, ÀΰøÀû ÀçÁ¶ÇÕÀ¯ÀüÀÚ¸¦ ¼÷ÁÖ¼¼Æ÷¿¡¼ ÇüÁúÀ» ¹ßÇö½ÃŰ´Â µ¥ ÃÖÃÊ·Î ¼º°øÇÑ °ÍÀº 1973³â F. J. ÄÚº¥ µîÀÌ´Ù. ÀÌ ÀçÁ¶ÇÕ DNA ±â¼úÀº ¼¼±ÕÆÄÁö, Çö󽺹̵忡 °üÇÑ ¿¬±¸¿Í DNA¿¡ ÀÛ¿ëÇÏ´Â È¿¼Òµé, ƯÈ÷ Á¦ÇÑÈ¿¼Ò¿Í DNA ¿¬°áÈ¿¼Ò¿¡ °üÇÑ ¿¬±¸¿¡ ÀÇÁ¸ÇÏ¿´´Ù. À¯Àü°øÇÐÀÇ ¹ßÀüÀº ¿ì¸® ¼¼°è¸¦ ¹Ù²Ü ¼ö ÀÖÀ» °ÍÀ¸·Î ³»´Ùº¸°í ÀÖ´Ù. ¾ÏÀ» Á¦¾ÐÇÏ°í ³ëȸ¦ ¹æÁöÇÒ ¼ö ÀÖ¾î À¯Àü°øÇÐÀº °á±¹ ¿À´ÃÀÇ Àΰ£ÀÌ ¾È°í ÀÖ´Â ¿¡³ÊÁö-½Ä·®-ÀÇ·á µîÀÇ ¹®Á¦¸¦ ÇØ°áÇØ ÁÙ ¼ö ÀÖ´Â °¡´É¼ºÀ» Áö´Ñ´Ù. ÀÌ ¶§¹®¿¡ À¯Àü°øÇÐÀº ¡®Á¦3ÀÇ »ê¾÷Çõ¸í¡¯À̶ó°í ÇÒ ¼ö ÀÖ°í, µû¶ó¼ ±× °³¹ßÀ» À§ÇÏ¿© ¿Â ¼¼°èÀÇ ±â¾÷µéÀÌ ÀÌÀÇ ¿¬±¸°³¹ß¿¡ Âø¼öÇÏ°í ±¹°¡µéµµ Àü·«±â¼ú·Î ´Ù·ç¾î ÁýÁ¢ À°¼º¿¡ ¹ÚÂ÷¸¦ °¡Çϰí ÀÖ´Ù. ¿ì¸®³ª¶ó¿¡¼µµ 1982³âºÎÅÍ À¯Àü°øÇÐ ºÐ¾ß¸¦ ±¹°¡°¡ À°¼ºÇØ¾ß ÇÒ Æ¯Á¤¿¬±¸ ºÐ¾ß·Î ÁöÁ¤Çϰí ÀÖ´Ù. |
||
| ¿µ¹® | genetic code | ÇÑ±Û | À¯ÀüºÎÈ£ |
|---|---|---|---|
| ¼³¸í | ±æ°Ô ´Ã¾î¼ ÀÖ´Â DNA»ç½½ÀÇ À¯ÀüÁ¤º¸°¡ °¢°¢ÀÇ ¾Æ¹Ì³ë»ê¿¡ ´ëÀÀÇÏ¿© ´Ü¹éÁúÀÇ ÇÕ¼º¿¡ »ç¿ëµÉ ¼ö ÀÖ°Ô ÀÐÇôÁö´Â ¹æ¹ý. DNA ºÐÀÚ´Â °¢°¢ÀÇ Deoxyribonucleotide°¡ ¿¬°áµÇ¾î¼ ÀÌ·ç´Â ±¸Á¶ÀÌ´Ù. ÀÌDeoxyribonucleolide´Â ´ç, Àλê, ±×¸®°í ¿°±â·Î ÀÌ·ç¾îÁ® ÀÖ´Ù. ´ç°ú ÀλêÀº °¢°¢ÀÇ Deoxyribonucleotide°¡ ¿¬°áµÇ°Ô À¯ÁöÇØÁÖ´Â ¿ªÇÒÀ» ÇÏ°í ¿°±â°¡ À¯ÀüÁ¤º¸¸¦ °¡Áö°í ÀÖÀ¸¸ç ÀÌ ¿°±âÀÇ ¹è¿ÀÌ À¯ÀüÁ¤º¸ Áï ´Ü¹éÁúÀÇ ÇÕ¼º¿¡ ÇÊ¿äÇÑ Á¤º¸¸¦ °¡Áö°í ÀÖ´Ù. DNA¸¦ ÀÌ·ç´Â ¿°±â´Â 4°³·Î ¾Æµ¥´Ñ(adenine), ±¸¾Æ´Ñ(guanine), Ƽ¹Î(thymine), ½ÃÅä½Å(cytosine)ÀÇ 4°¡ÁöÀÌ´Ù. 4°³ÀÇ ¿°±â°¡ ¼¯¿©ÀÖ´Â ¹è¿À» ÇÑ °³ÀÇ ´Ü¹éÁú·Î ÇÕ¼ºÀ» Çϱâ À§Çؼ´Â ÀÌ ¹è¿À» ÇØµ¶ÇÏ´Â ¹æ¹ýÀÌ ÀÖ¾î¾ß ÇÑ´Ù. Áï ±× ¹æ¹ýÀº 3°³ÀÇ ¿°±âÀÇ ¹è¿À» ÇϳªÀÇ ¾Æ¹Ì³ë»ê¿¡ ´ëÀÀ½ÃÄѼ °¢ ¾Æ¹Ì³ë»êÀÇ ¼¿À» Á¤ÇÏ°í ´Ü¹éÁúÀ» ¸¸µå´Â °ÍÀÌ´Ù. ¿¹¸¦ µé¸é cytosine-cytosine-cytosineÀ̶ó´Â ¹è¿Àº prolineÀ̶ó´Â ´Ü¹éÁúÀ» ÀǹÌÇÏ´Â °ÍÀ¸·Î ÀÐÇôÁö°Ô µÈ´Ù. ÀÌ·¸°Ô ¾Æ¹«·± ±ÔÄ¢ÀÌ ¾ø´Â °Í °°Àº ¿°±â¼¿À» ÇϳªÀÇ ¾Æ¹Ì³ë»ê°ú ´ëÀÀ½ÃÄѼ Àд ¹æ¹ýÀÌ À¯ÀüºÎÈ£ÀÌ´Ù. |
||
| MSS | Marshall-Smith syndrome; massage; Medical Superintendents' Society; Medicare Statistical System; men... |
|---|---|
| AGA | accelerated growth area; allergic granulomatosis and angiitis; American Gastroenterological Associat... |
| Gen | genetics, genetic; genus |
| genet | genetic, genetics |
| GENETOX | Genetic Toxicology [data base] |
| DSC | Dynamic susceptibility contrast |
|---|---|
| GAERS | Genetic Absence Epilepsy Rat from Strasbourg |
| GA | Genetic Algorithm |
| GH | Genetic Hemochromatosis |
| GSE | genetic suppressor element |
| BRCA1 breast cancer susceptibility gene | This mutated (changed) version of the BRCA1 gene makes a person susceptible to developing breast cancer. (12 Dec 1998) |
|---|---|
| breast cancer susceptibility genes | Inherited factors that predispose to breast cancer. Put otherwise, these genes make one more susceptible to the disease and so increase the risk of developing breast cancer. Two of these genes, BRCA1 and BRCA2, have been identified (and prominently publicised). Several other genes (those for the Li-Fraumeni syndrome, Cowden disease, Muir-Torre syndrome, and ataxia-telangiectasia) are also known to predispose to breast cancer. However, since all of these known breast cancer susceptibility genes together do not account for more than a minor fraction (1/5th at most) of breast cancer that clusters in families, it is clear that more breast cancer genes remain to be discovered. (12 Dec 1998) |
| cancer, breast, susceptibility genes | Inherited factors that predispose to breast cancer. Put otherwise, these genes make one more susceptible to the disease and so increase the risk of developing breast cancer. Two of these genes, BRCA1 and BRCA2, have been identified (and prominently publicised). Several other genes (those for the Li-Fraumeni syndrome, Cowden disease, Muir-Torre syndrome, and ataxia-telangiectasia) are also known to predispose to breast cancer. However, since all of these known breast cancer susceptibility genes together do not account for more than a minor fraction (1/5th at most) of breast cancer that clusters in families, it is clear that more breast cancer genes remain to be discovered. (12 Dec 1998) |
| cancer susceptibility gene | tumour suppressor gene |
| genes, breast cancer susceptibility | Inherited factors that predispose to breast cancer. Put otherwise, these genes make one more susceptible to the disease and so increase the risk of developing breast cancer. Two of these genes, BRCA1 and BRCA2, have been identified (and prominently publicised). Several other genes (those for the Li-Fraumeni syndrome, Cowden disease, Muir-Torre syndrome, and ataxia-telangiectasia) are also known to predispose to breast cancer. Howeverm, since all of these known breast cancer susceptibility genes together do not account for more than a minor fraction (1/5th at most) of breast cancer that clusters in families, it is clear that more breast cancer genes remain to be discovered. See related entries to: BRCA1; BRCA2; Breast cancer, familial. (12 Dec 1998) |
| colourimetric caries susceptibility test | A colourimetric test for determining dental caries activity or susceptibility based on the rate of acid production by acidogenic oral microorganisms (e.g., lactobacillus) in a glucose medium, using bromcresol green as the indicator, and producing a colour change from green to yellow. Synonym: colourimetric caries susceptibility test. (05 Mar 2000) |
| susceptibility | Origin: Cf. F. Susceptibilite. 1. The state or quality of being susceptible; the capability of receiving impressions, or of being affected. 2. Specifically, capacity for deep feeling or emotional excitement; sensibility, in its broadest acceptation; impressibility; sensitiveness. <physics> Magnetic susceptibility, the intensity of magnetization of a body placed in a uniform megnetic field of unit strength. Synonym: Capability, sensibility, feeling, emotion. Source: Websters Dictionary (01 Mar 1998) |
| susceptibility testing | The determination of the ability of an antibiotic to kill or inhibit the growth of bacteria. (05 Mar 2000) |
| disease susceptibility | A constitution or condition of the body which makes the tissues react in special ways to certain extrinsic stimuli and thus tends to make the individual more than usually susceptible to certain diseases. (12 Dec 1998) |
| genetic | <biology> Pertaining to reproduction or to birth or origin. (07 May 1998) |
| genetic amplification | A process for producing an increase in pertinent genetic material, particularly for increasing the proportion of plasmid DNA to that of bacterial DNA. Includes the production of extrachromosomal copies of the genes for RNA. (05 Mar 2000) |
| genetic assimilation | <genetics> A situation in which a characteristic that is normally expressed only in certain environmental situations becomes fixed in a population so that it no longer requires environmental factors to be expressed. (07 May 1998) |
| genetic association | The occurrence together in a population, more often than can be readily explained by chance, of two or more traits of which at least one is known to be genetic. (05 Mar 2000) |
| genetic block | <biochemistry, molecular biology> An obstruction in a biochemical pathway caused by a mutation that has crippled production of an enzyme critical to the pathway. (07 May 1998) |
| genetic burden | The genetic debt due to harmful mutation but as yet undischarged. (In a large population of fixed size every mutation with diminished genetic fitness will eventually become extinct and depending on the details of inheritance and phenotype must be paid for by a fixed number of genetic deaths per mutation, the genetic debt.) (05 Mar 2000) |
Á¦Ç°¸í |
ÆÇ¸Å»ç |
º¸ÇèÄÚµå | ¼ººÐ/ÇÔ·® | ±¸ºÐ/º¸Çè±Þ¿© |
|---|
Á¦Ç°¸í |
ÆÇ¸Å»ç |
º¸ÇèÄÚµå | ¼ººÐ/ÇÔ·® | ±¸ºÐ/º¸Çè±Þ¿© |
|---|