| ¿µ¹® | genetic engineering | ÇÑ±Û | À¯Àü°øÇÐ |
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| ¿µ¹® | genetic code | ÇÑ±Û | À¯ÀüºÎÈ£ |
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| MAD | Major Antigenic Determinant |
|---|---|
| MDM | Minor Determinant Mixture |
| AD | accident dispensary; acetate dialysis; active disease; acute dermatomyositis; addict, addiction; ade... |
| HBsAg/adr | hepatitis B surface antigen manifesting group-specific determinant a and subtype-specific determinan... |
| LAD | lactic acid dehydrogenase; left anterior descending [artery]; left axis deviation; leukocyte adhesio... |
| CRD | Cross Reacting Determinant |
|---|---|
| DDIA | double determinant immunoassay |
| MDM | minor determinant mixture |
| PND | principal Neutralizing Determinant |
| GAERS | Genetic Absence Epilepsy Rat from Strasbourg |
| genetic determinant | Any antigenic determinant or identifying characteristic, particularly those of allotypes. Synonym: genetic marker. (05 Mar 2000) |
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| antigenic determinant | That part of an antigenic molecule against which a particular immune response is directed. For instance a tetra to penta peptide sequence in a protein, a tri to penta glycoside sequence in a polysaccharide. In the animal most antigens will present several or even many antigenic determinants simultaneously. See: hapten. (18 Nov 1997) |
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| mathematical determinant | A formal algebraic operation on the terms of a square matrix of quantities, fundamental in solving multiple simultaneous equations and widely used in regression analysis, notably in epidemiology and quantitative genetics. If determinant is zero, the equations have no unambiguous solution. (05 Mar 2000) |
| determinant | 1. That which serves to determine; that which causes determination. 2. <mathematics> The sum of a series of products of several numbers, these products being formed according to certain specified laws; thus, the determinant of the nine numbers. Is a b' c'' a b'' c' + a' b'' c] a' b c'' + a'' b' c. The determinant is written by placing the numbers from which it is formed in a square between two vertical lines. The theory of determinants forms a very important branch of modern mathematics. 3. <logic> A mark or attribute, attached to the subject or predicate, narrowing the extent of both, but rendering them more definite and precise. Source: Websters Dictionary (01 Mar 1998) |
| determinant group | That part of an antigenic molecule against which a particular immune response is directed. For instance a tetra to penta peptide sequence in a protein, a tri to penta glycoside sequence in a polysaccharide. In the animal most antigens will present several or even many antigenic determinants simultaneously. See: hapten. (18 Nov 1997) |
| idiotypic antigenic determinant | The antigenic specificites defined by the unique sequences (idiotopes) of the antigen combining site. Thus anti-idiotype antibodies combine with those specific sequences, may block immunological reactions and may resemble the epitope to which the first antibody reacts. (18 Nov 1997) |
| isoallotypic determinant | <genetics> Genetic determinant's that are both isotypic and allotypic in that they appear in all members of at least one subclass of immunoglobulin but only in some members of another subclass of the same species. (05 Mar 2000) |
| genetic | <biology> Pertaining to reproduction or to birth or origin. (07 May 1998) |
| genetic amplification | A process for producing an increase in pertinent genetic material, particularly for increasing the proportion of plasmid DNA to that of bacterial DNA. Includes the production of extrachromosomal copies of the genes for RNA. (05 Mar 2000) |
| genetic assimilation | <genetics> A situation in which a characteristic that is normally expressed only in certain environmental situations becomes fixed in a population so that it no longer requires environmental factors to be expressed. (07 May 1998) |
| genetic association | The occurrence together in a population, more often than can be readily explained by chance, of two or more traits of which at least one is known to be genetic. (05 Mar 2000) |
| genetic block | <biochemistry, molecular biology> An obstruction in a biochemical pathway caused by a mutation that has crippled production of an enzyme critical to the pathway. (07 May 1998) |
| genetic burden | The genetic debt due to harmful mutation but as yet undischarged. (In a large population of fixed size every mutation with diminished genetic fitness will eventually become extinct and depending on the details of inheritance and phenotype must be paid for by a fixed number of genetic deaths per mutation, the genetic debt.) (05 Mar 2000) |
| genetic carrier | An unaffected heterozygote bearing a usually harmful recessive gene, a cancer that bears a dominant but latent age-dependent trait to have offspring with unbalanced karyotypes. (05 Mar 2000) |
| genetic code | <molecular biology> Relationship between the sequence of bases in nucleic acid and the order of amino acids in the polypeptide synthesised from it. A sequence of three nucleic acid bases (a triplet) acts as a codeword (codon) for one amino acid. (18 Nov 1997) |
| genetic colonisation | <molecular biology> The process of a parasite (such as a virus) inserting genes into a host's genome which cause the host cell to synthesise products that are only useful to the parasite. (07 May 1998) |
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