| TAT | 1) Thematic Apperception Test; ÁÖÁ¦ Åë°¢ °Ë»ç 2) (Equine) Tetanus Anti-Toxin; Ç×... |
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| TAT | tetanus antitoxin; thematic apperception test; thematic aptitude test; thrombin-antithrombin complex... |
| ISG | IFN stimulated genes |
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| mdr | Multidrug resistance genes |
| stx | Shiga toxin genes |
| or genes | gene |
| rDNA | ribosomal DNA genes |
| genes, tat | DNA sequences that form the coding region for the protein responsible for trans-activation of transcription (tat) in human immunodeficiency virus (HIV). (12 Dec 1998) |
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| gene products, tat | Trans-acting transcription factors. Nuclear proteins whose expression is required for HIV viral replication. The tat protein stimulates HIV-ltr-driven RNA synthesis for both viral regulatory and viral structural proteins. Tat stands for trans-activation of transcription. (12 Dec 1998) |
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| tat | <protein> An HIV protein that helps produce new complete HIV RNA genomes (see), and ultimately new virus, from the HIV DNA genetic template present in infected cells. Tat may also be involved in: 1) the reactivation of other latent viruses in people with AIDS, such as JC virus, the cause of PML, 2) the development of AIDS-related KS by stimulating the formation of new blood vessels, and 3) the triggering of anergy and apoptosis in CD4 cells. (16 Dec 1997) |
| tat-associated kinase | <enzyme> Abbreviated tak; binds to activation domain of tat Registry number: EC 2.7.1.- Synonym: p-tefb, positive transcriptional elongation factor b (26 Jun 1999) |
| Tat protein | <molecular biology> Transactivator protein from lentiviruses, notably HIV. Sequence specific RNA binding proteins that recognise TAR RNA. Peptides from this protein are potent neurotoxins, implying a possible route for HIV mediated toxicity. (18 Nov 1997) |
| breast cancer susceptibility genes | Inherited factors that predispose to breast cancer. Put otherwise, these genes make one more susceptible to the disease and so increase the risk of developing breast cancer. Two of these genes, BRCA1 and BRCA2, have been identified (and prominently publicised). Several other genes (those for the Li-Fraumeni syndrome, Cowden disease, Muir-Torre syndrome, and ataxia-telangiectasia) are also known to predispose to breast cancer. However, since all of these known breast cancer susceptibility genes together do not account for more than a minor fraction (1/5th at most) of breast cancer that clusters in families, it is clear that more breast cancer genes remain to be discovered. (12 Dec 1998) |
| cancer, breast, susceptibility genes | Inherited factors that predispose to breast cancer. Put otherwise, these genes make one more susceptible to the disease and so increase the risk of developing breast cancer. Two of these genes, BRCA1 and BRCA2, have been identified (and prominently publicised). Several other genes (those for the Li-Fraumeni syndrome, Cowden disease, Muir-Torre syndrome, and ataxia-telangiectasia) are also known to predispose to breast cancer. However, since all of these known breast cancer susceptibility genes together do not account for more than a minor fraction (1/5th at most) of breast cancer that clusters in families, it is clear that more breast cancer genes remain to be discovered. (12 Dec 1998) |
| genes | Located in the nucleus of the cell, genes contain hereditary information that is transferred from cell to cell. (09 Oct 1997) |
| genes, abl | Retrovirus-associated DNA sequences (abl) originally isolated from the abelson murine leukaemia virus (ab-mulv). The proto-oncogene abl (c-abl) codes for a protein that is a member of the tyrosine kinase family. The human c-abl gene is located at 9q34.1 on the long arm of chromosome 9. It is activated by translocation to bcr on chromosome 22 in chronic myelogenous leukaemia. (12 Dec 1998) |
| genes, apc | Tumour suppressor genes located in the 5q21 region on the long arm of chromosome 5. The mutation of these genes is associated with familial adenomatous polyposis (apc stands for adenomatous polyposis coli) and gardner's syndrome, as well as some sporadic colourectal cancers. (12 Dec 1998) |
| genes, arac | Regulatory genes which encode a cyclic AMP receptor protein required for l-arabinose utilization in e. Coli. It is an example of positive control or regulation of gene expression in the bacterial operon. (12 Dec 1998) |
| genes, archaeal | The genetic material of archaea. (12 Dec 1998) |
| genes, bacterial | The genetic material of bacteria. (12 Dec 1998) |
| genes, bcl-1 | The B-cell leukaemia/lymphoma-1 genes, associated with various neoplasms when overexpressed. Overexpression results from the t(11;14) translocation, which is characteristic of mantle zone-derived B-cell lymphomas. The human c-bcl-1 gene is located at 11q13 on the long arm of chromosome 18. (12 Dec 1998) |
| genes, bcl-2 | The B-cell leukaemia/lymphoma-2 genes, responsible for blocking apoptosis in normal cells, and associated with follicular lymphoma when overexpressed. Overexpression results from the t(14;18) translocation. The human c-bcl-2 gene is located at 18q24 on the long arm of chromosome 18. (12 Dec 1998) |
| genes, BRCA1 | Tumour suppressor genes located on human chromosome 17q12-21. The mutation of these genes is associated with the formation of familial breast and ovarian cancer. (12 Dec 1998) |
Synonyms : Gene, tat, tat Gene
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