| PHOX | paired mesoderm homeobox [gene] |
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| PMX | paired mesoderm homeobox [gene] |
| HOX | Homeobox |
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| ISG | IFN stimulated genes |
| mdr | Multidrug resistance genes |
| stx | Shiga toxin genes |
| or genes | gene |
| genes, homeobox | Highly conserved DNA sequences which have been identified in specific gene transcripts ranging from those of drosophila melanogaster to mouse and human. Homeobox genes function, in part, to generate DNA-binding proteins with an evolutionary conserved approximately 60-residue sequence (homeodomain proteins). (12 Dec 1998) |
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| homeobox | <molecular biology> Conserved DNA sequence originally detected by DNA hybridisation in many of the genes that give rise to homeotic and segmentation mutants in Drosophila. The homeobox consists of about 180 nucleotides coding for a sequence of 60 amino acids in a protein, sometimes termed the homeodomain, of which about 80-90% are identical in the various homeodomains identified from Drosophila. Homeoboxes have also been detected in the genomes of vertebrates, with about 75% amino acid homology and a similar sequence has been found in the MAT gene of yeast. The homeobox codes for a protein domain that is involved in binding to DNA. Three subfamilies of homeobox containing proteins can be identified, based on the archetypal Drosophila genes engrailed, Antennapedia and paired. Interestingly, linear order within genome maps to order of expression in embryo. This may be required for the transcriptional silencing of certain homeotic genes (see Polycomb). (11 Nov 1997) |
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| breast cancer susceptibility genes | Inherited factors that predispose to breast cancer. Put otherwise, these genes make one more susceptible to the disease and so increase the risk of developing breast cancer. Two of these genes, BRCA1 and BRCA2, have been identified (and prominently publicised). Several other genes (those for the Li-Fraumeni syndrome, Cowden disease, Muir-Torre syndrome, and ataxia-telangiectasia) are also known to predispose to breast cancer. However, since all of these known breast cancer susceptibility genes together do not account for more than a minor fraction (1/5th at most) of breast cancer that clusters in families, it is clear that more breast cancer genes remain to be discovered. (12 Dec 1998) |
| cancer, breast, susceptibility genes | Inherited factors that predispose to breast cancer. Put otherwise, these genes make one more susceptible to the disease and so increase the risk of developing breast cancer. Two of these genes, BRCA1 and BRCA2, have been identified (and prominently publicised). Several other genes (those for the Li-Fraumeni syndrome, Cowden disease, Muir-Torre syndrome, and ataxia-telangiectasia) are also known to predispose to breast cancer. However, since all of these known breast cancer susceptibility genes together do not account for more than a minor fraction (1/5th at most) of breast cancer that clusters in families, it is clear that more breast cancer genes remain to be discovered. (12 Dec 1998) |
| genes | Located in the nucleus of the cell, genes contain hereditary information that is transferred from cell to cell. (09 Oct 1997) |
| genes, abl | Retrovirus-associated DNA sequences (abl) originally isolated from the abelson murine leukaemia virus (ab-mulv). The proto-oncogene abl (c-abl) codes for a protein that is a member of the tyrosine kinase family. The human c-abl gene is located at 9q34.1 on the long arm of chromosome 9. It is activated by translocation to bcr on chromosome 22 in chronic myelogenous leukaemia. (12 Dec 1998) |
| genes, apc | Tumour suppressor genes located in the 5q21 region on the long arm of chromosome 5. The mutation of these genes is associated with familial adenomatous polyposis (apc stands for adenomatous polyposis coli) and gardner's syndrome, as well as some sporadic colourectal cancers. (12 Dec 1998) |
| genes, arac | Regulatory genes which encode a cyclic AMP receptor protein required for l-arabinose utilization in e. Coli. It is an example of positive control or regulation of gene expression in the bacterial operon. (12 Dec 1998) |
| genes, archaeal | The genetic material of archaea. (12 Dec 1998) |
| genes, bacterial | The genetic material of bacteria. (12 Dec 1998) |
| genes, bcl-1 | The B-cell leukaemia/lymphoma-1 genes, associated with various neoplasms when overexpressed. Overexpression results from the t(11;14) translocation, which is characteristic of mantle zone-derived B-cell lymphomas. The human c-bcl-1 gene is located at 11q13 on the long arm of chromosome 18. (12 Dec 1998) |
| genes, bcl-2 | The B-cell leukaemia/lymphoma-2 genes, responsible for blocking apoptosis in normal cells, and associated with follicular lymphoma when overexpressed. Overexpression results from the t(14;18) translocation. The human c-bcl-2 gene is located at 18q24 on the long arm of chromosome 18. (12 Dec 1998) |
| genes, BRCA1 | Tumour suppressor genes located on human chromosome 17q12-21. The mutation of these genes is associated with the formation of familial breast and ovarian cancer. (12 Dec 1998) |
| genes, breast cancer susceptibility | Inherited factors that predispose to breast cancer. Put otherwise, these genes make one more susceptible to the disease and so increase the risk of developing breast cancer. Two of these genes, BRCA1 and BRCA2, have been identified (and prominently publicised). Several other genes (those for the Li-Fraumeni syndrome, Cowden disease, Muir-Torre syndrome, and ataxia-telangiectasia) are also known to predispose to breast cancer. Howeverm, since all of these known breast cancer susceptibility genes together do not account for more than a minor fraction (1/5th at most) of breast cancer that clusters in families, it is clear that more breast cancer genes remain to be discovered. See related entries to: BRCA1; BRCA2; Breast cancer, familial. (12 Dec 1998) |
| genes, cdc | Genes that code for proteins that regulate the cell division cycle. These genes form a regulatory network that culminates in the onset of mitosis by activating the p34cdc2 protein (protein p34cdc2). (12 Dec 1998) |
| genes, dcc | Tumour suppressor genes located in the 18q21-qter region of human chromosome 18. The absence of these genes is associated with the formation of colourectal cancer (dcc stands for deleted in colourectal cancer). The products of these genes show significant homology to neural cell adhesion molecules and other related cell surface glycoproteins. (12 Dec 1998) |
Synonyms : Genes, Homeo Box, Homeo Box, Homeo Box Sequence, Homeo Boxes, Homeobox, Homeoboxes, Sequence, Homeo Box, Gene, Homeo Box, Gene, Homeobox, Gene, Homeotic, Homeo Box Gene, Homeo Box Genes, Homeo Box Sequences, Homeobox Gene, Homeobox Genes, Homeobox Sequences
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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