| ¿µ¹® | gene therapy | ÇÑ±Û | À¯ÀüÀÚ¿ä¹ý |
|---|---|---|---|
| ¼³¸í | À¯Àüº´À» Ä¡·áÇÒ ¸ñÀûÀ¸·Î, Á¤»óÀûÀ¸·Î ±â´ÉÇÏ´Â ´ÜÀÏÀ¯ÀüÀÚ È¤Àº º¹¼öÀ¯ÀüÀÚ¸¦ ¾î¶² ±â¿ø¿¡¼ ¾ò¾î³»¾î »ý¼¼Æ÷¿¡ µµÀÔÇÏ´Â °Í. À¯Àü¹°ÁúÀº À¯ÀüÀÚ»ðÀÔ Á¶ÀÛ¿¡ ÀÇÇØ ¼ö¿ë¼¼Æ÷¿¡·Î µµÀԵȴÙ. Áï, À¯ÀüÀÚ¸¦ ³¢¿ö ³ÖÀº »õ·Î¿î ¼¼Æ÷¸¦ »ç¿ëÇÏ´Â Ä¡·á·Î¼ 1980³â ¹Ì±¹ÀÇ ÇÐÀÚ°¡ ÁöÁßÇØºóÇ÷ȯÀÚ¿¡°Ô °ÇàÇÏ¿© ºñÆÇÀ» ¹Þ¾ÒÁö¸¸, ¹Ì±¹ ±¹¸³º¸°Ç¿¬±¸¼Ò´Â 1990³â 9¿ù ¾Æµ¥³ë½Å µ¥¾Æ¹Ì³ª¾ÆÁ¦(adenosine deaminase, ADA) °áÇÌÁõ ȯÀÚÀÇ ¸²ÇÁ±¸¿¡ ADA À¯ÀüÀÚ¸¦ ³¢¿ö ³Ö´Â Ä¡·á¸¦ ½ÃÀÛÇÑ ÀÌ·¡ ÇöÀç´Â ¾ÏÀ» Æ÷ÇÔÇÑ ¸¹Àº Áúº´µéÀ» Ä¡·áÇÏ´Â ¸ñÀûÀ¸·Î ¾²ÀδÙ. |
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| ¿µ¹® | gene | ÇÑ±Û | À¯ÀüÀÚ |
|---|---|---|---|
| ¼³¸í | À¯ÀüÀÚ´Â ±æ°Ô ¶ì¸¦ Çü¼ºÇÑ DNAºÐÀÚÀÇ ÀϺκÐÀ¸·Î ÇÑ °¡Áö ¹°ÁúÀ» ¸¸µå´Âµ¥ ÇÊ¿äÇÑ ¸ðµç Á¤º¸¸¦ °®Ãá ±â´ÉÀûÀÎ ´ÜÀ§ÀÌ´Ù. ¿¹¸¦ µé¾î Àν¶¸°À̶ó´Â ¹°ÁúÀÇ À¯ÀüÀÚ¶ó°í ÇÏ¸é »ç¶÷ÀÇ ¼¼Æ÷³»¿¡ ÀÖ´Â ±ä DNA ºÐÀÚ Áß¿¡¼ Àν¶¸°À̶ó´Â ¹°ÁúÀ» ¸¸µå´Âµ¥ ÇÊ¿äÇÑ ¸ðµç Á¤º¸¸¦ °¡Áö°í ÀÖ´Â ÇÑ ºÎºÐÀ» °¡¸®Å°´Â ¸»ÀÌ´Ù. °íÀüÀûÀÎ »ý¹°Çп¡¼´Â À¯ÀüÀÚ°¡ Ç¥ÇöÇüÀ» °áÁ¤Çϰųª ÁöÁ¤ÇÏ´Â ¿°»öüÀÇ ÀϺκÐÀ̶ó°í Á¤ÀǵǾúÁö¸¸, ¿À´Ã³¯¿¡´Â À¯ÀüÀÚ¿¡ ´ëÇØ¼ ºÐÀÚÀû Á¤Àǰ¡ Á¦¾ÈµÇ°í ÀÖÀ¸¸ç ±× Á¤ÀÇ´Â ÇϳªÀÇ À¯ÀüÀÚ´Â ÇϳªÀÇ È¿¼Ò¸¦ °áÁ¤ ¶Ç´Â ¾ÏÈ£ÈÇÏ´Â À¯Àü¹°ÁúÀÇ ÀϺκÐÀ̶ó´Â °³³äÀ¸·Î À̰ÍÀÌ À̸¥¹Ù 1°³ÀÇ À¯ÀüÀÚ 1°³ È¿¼Ò°¡¼³(one gene-one enzyme hypothesis)ÀÌ´Ù. Áï 1°³ÀÇ À¯ÀüÀÚ´Â 1°³ÀÇ È¿¼Ò¸¦ Á¦ÀÛÇϴµ¥ ÇÊ¿äÇÑ À¯ÀüÁ¤º¸¸¦ °¡Áø´Ù´Â °ÍÀÌ´Ù. ÇöÀç ÀÌ °¡¼³ÀÌ ¹Þ¾Æµé¿©Áö°í ÀÖ´Ù. |
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| ¿µ¹® | family therapy | ÇÑ±Û | °¡Á·¿ä¹ý |
|---|---|---|---|
| ¼³¸í | °¡Á·À» Ä¡·á ´ë»óÀ¸·Î ÇÏ´Â ½É¸®¿ä¹ý ÁßÀÇ Çϳª. °¡Á·ÁßÀÇ ¹®Á¦´Â ¹®Á¦¸¦ °¡Áø °³Àθ¸ÀÌ ¾Æ´Ï¶ó ¹®Á¦ °¡Á·À» ´ë»óÀ¸·Î ÇØ°áÇØ ³ª°¥ Çʿ䰡 ÀÖ´Ù´Â ÀνÄÀ» ¹ÙÅÁÀ¸·Î ÇÏ¿© °¡Á· ÀüüÀÇ ½É¸®Àû ¼º¼÷À» ¸ñÇ¥·Î ÇÑ ¿ä¹ýÀÌ´Ù. Å©°Ô ³ª´©¾î °¡Á· ÁßÀÇ Æ¯Á¤ÀÎÀ» ´ë»óÀ¸·Î ÇÏ¿© °¢°¢ ´Ù¸¥ µ¶¸³µÈ Ä¡·á¸¦ ÇÏ´Â º´Çà½É¸®¿ä¹ý°ú °¡Á· Àüü¸¦ µ¿½Ã ¸éÁ¢ÇÏ´Â ¹æ¹ýÀ» ÁÖ·Î ÇÏ´Â ÇÕµ¿°¡Á·¿ä¹ýÀÌ Àִµ¥, ƯÈ÷ ÈÄÀÚ¸¦ °¡¸®ÄÑ °¡Á·¿ä¹ý À̶ó°í ÇÏ´Â °æ¿ì°¡ ¸¹´Ù. |
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| ¿µ¹® | intracavitary therapy | ÇÑ±Û | °³»¿ä¹ý |
|---|---|---|---|
| ¼³¸í | ü°³», Áï ÀÔ¾È, ÄÚ¾È, Àεΰ, ½Äµµ, °ðâÀÚ, Áú, Àڱøñ, ¹æ±¤ µîÀÇ ³»°¿¡, ¶§·Î´Â º´ÅÍ¿¡ ÀÇÇØ »ý±ä °øµ¿³»¿¡ ¹æ»ç¼±À» »ðÀÔÇØ¼ Ä¡·áÇÏ´Â °ÍÀ» ¸»ÇÑ´Ù. ÁÖ·Î Á¾¾çÀÇ Ä¡·á¸¦ ¸ñÀûÀ¸·Î ÇÑ´Ù. |
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| ¿µ¹® | hyperbaric oxygenation therapy | ÇÑ±Û | °í¾Ð»ê¼Ò¿ä¹ý |
|---|---|---|---|
| ¼³¸í | ´ë±â¾Ðº¸´Ù ³ôÀº ±â¾Ðȯ°æÀ» ÀΰøÀûÀ¸·Î ¸¸µé¾î ±× ¾È¿¡¼ °í³óµµÀÇ »ê¼Ò¸¦ ÈíÀÔ½ÃŰ´Â ¿ä¹ý. Çѱ¹¿¡¼ ¿¬Åº°¡½º·Î ´ëÇ¥µÇ´Â ÀÏ»êÈź¼ÒÀÇ ±Þ¼ºÁßµ¶ÀÇ Ä¡·á¿¡ ¸¹ÀÌ ÀÌ¿ëµÈ °ÍÀ¸·Î, º¸Åë 3´ë±â¾Ð Á¤µµ·Î °¡¾ÐµÈ °í¾Ð»ê¼Ò½ÇÀ̳ª °í¾Ð»ê¼ÒÅÊÅ© ¼Ó¿¡ ȯÀÚ¸¦ ³õ°í Àü½Å¿¡ »ê¼Ò¸¦ ÈíÀÔ½ÃŲ´Ù. °í¾Ð½ÇÀº Å©°í ÀÛÀº ¿©·¯ °¡Áö°¡ ÀÖÀ¸¸ç, ±¸Á¶»ó 1½Ç½Ä-2½Ç½Ä-´Ù½Ç½ÄÀÌ ÀÖ´Ù. °¡¾Ð °¡½ºÀÇ Á¾·ù¿¡´Â »ê¼Ò-°ø±â-È¥ÇÕ °¡½ºµîÀÌ ÀÖ°í, 2~3 ´ë±â¾Ð ¶Ç´Â ±× ÀÌ»óÀÇ °í¾Ð ȯ°æÀ» ¸¸µç´Ù. ÀÓ»óÀûÀ¸·Î ÀÀ¿ë¹üÀ§°¡ ³Ð¾î¼ ±â°èÀû È¿°ú¿¡ ÀÇÇÏ¿© Àá¼öºÎº´À̳ª âÀÚ°ü¸¶ºñ¿¡ ÀÇÇÑ Ã¢ÀÚÆó»ö Ä¡·á µî¿¡ À¯È¿Çϰí, °¡½º±ËÀú µîÀÇ ¹«»ê¼Ò¼º ¼¼±Õ°¨¿°¿¡¼µµ ÀÌ¿ëµÈ´Ù. ¶Ç »ê¼Ò¿î¹ÝÈ¿°ú¿¡ ÀÇÇÏ¿© ÀÏ»êÈź¼Ò-½É±Ù°æ»ö-³ú»öÀüÁõ-ÃâÇ÷¼îÅ©¿¡ ÀÇÇÑ ±Þ¼ºÀÇ Á¶Á÷»ê¼Ò°áÇÌÀÇ Ä¡·á¿¡ À¯È¿ÇÏ´Ù. ¶Ç ¾ÏÀÇ ¹æ»ç¼±¿ä¹ý¿¡ º´¿ëÇϸé ÀÌ ¿ä¹ýÀ¸·Î ¾Ï¼¼Æ÷ÀÇ ºÐ¿ÀÌ ¿Õ¼ºÇØÁ®, ¼¼Æ÷ºÐ¿ ÁßÀÎ ¼¼Æ÷¿¡ ¹æ»ç¼±À» Á¶»çÇÔÀ¸·Î½á ºÐ¿´É·ÂÀ» ¾ø¾Ö´Â µ¥ À¯È¿ÇÏ¿© °í¾Ð»ê¼ÒÈíÀÔÁ¶»ç¹ýÀ̶ó°í ÇÑ´Ù. |
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| ¿µ¹® | interstitial therapy | ÇÑ±Û | ±ÙÁ¢Ä¡·á |
|---|---|---|---|
| ¼³¸í | ÁÖ·Î Á¾¾çÀÇ Ä¡·á¸¦ ¸ñÀûÀ¸·Î ÇÏ¿© ÀÎü Á¶Á÷³»¿¡ ¹æ»ç¼± ¹°ÁúÀ» »ðÀÔÇÏ¿© ¹æ»ç¼±À» Á¶»çÇÏ´Â Ä¡·á¹ýÀÌ´Ù. Brachytherapy¶ó°íµµ ÇÑ´Ù. |
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| CT | calcitonin; calf testis; cardiac tamponade; cardiothoracic [ratio]; carotid tracing; carpal tunnel; ... |
|---|---|
| IT | immunological test; immunotherapy; implantation test; individual therapy; information technology; in... |
| MT | magnetization transfer; malaria therapy; malignant teratoma; mammary tumor; mammilothalamic tract; m... |
| GT | gait training; galactosyl transferase; gastrostomy; generation time; genetic therapy; gingiva treatm... |
| RT | radiologic technologist; radiotelemetry; radiotherapy; radium therapy; rapid tranquilization; reacti... |
| GDEPT | Gene directed enzyme prodrug therapy |
|---|---|
| ADT | Androgen deprivation therapy |
| ADEPT | Antibody Directed Enzyme Prodrug Therapy |
| ART | Antiretroviral therapy |
| ALT | Autolymphocyte therapy |
| gene therapy | <molecular biology> Treatment of a disease caused by malfunction of a gene, by stably transfecting the cells of the organism with the normal gene. (18 Nov 1997) |
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| germ line gene therapy | The repair or replacement of a defective gene within the gamete-forming tissues, which produces an inheritable change in an organisms genetic constitution. (09 Oct 1997) |
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| human gene therapy | <molecular biology, technique> Insertion of normal DNA directly into cells to correct a genetic defect. (09 Oct 1997) |
| somatic cell gene therapy | The repair or replacement of a defective gene within somatic tissue. (09 Oct 1997) |
| therapy, gene | Insertion of normal DNA directly into cells to correct a genetic defect. Gene therapy is the treatment of disease by replacing, altering, or supplementing a gene responsible for the disease. In gene therapy for cancer, for example, researchers are trying to bolster the body's natural capacity to combat cancer and make the tumour more sensitive to other kinds of therapy. Gene therapy, still in its early stages, holds great promise for the treatment of many diseases. (12 Dec 1998) |
| acupuncture therapy | Treatment of disease by inserting needles along specific pathways or meridians. The placement varies with the disease being treated. Heat or moxibustion and acupressure may be used in conjunction. (12 Dec 1998) |
| adjuvant therapy | <oncology, pharmacology> Treatment that is added to increase the effectiveness of a primary treatment. In cancer, adjuvant treatment usually refers to chemotherapy, hormonal therapy or radiation therapy after surgery to increase the likelihood of killing all cancer cells. (14 May 1997) |
| alternative therapy | A term given to nonconventional therapy usually given by persons who do not have a medical qualification. (16 Dec 1997) |
| analytic therapy | Short term for psychoanalytic therapy. (05 Mar 2000) |
| Antibody Directed Enzyme Prodrug Therapy | <pharmacology> A method for targeting a drug to a specific tissue, in which the targeting agent and the drug are administered separately. The drug is designed to be inactive (a prodrug) until it is converted by an enzyme, which is the targeting agent. The enzyme is coupled to an antibody that directs it to the tissue of interest. When the enzyme arrives at the tissue, the prodrug is activated only at that site, sparing other tissues from potentially toxic side effects. Acronym: ADEPT (14 Nov 1997) |
| anticoagulant therapy | The use of anticoagulant drugs to reduce or prevent intravascular or intracardiac clotting. (05 Mar 2000) |
| antisense therapy | Use of antisense DNA for the inhibition of translation of a specific gene product for therapeutic purposes. (05 Mar 2000) |
| art therapy | The use of art as an adjunctive therapy in the treatment of neurological, mental, or behavioural disorders. (12 Dec 1998) |
| autoserum therapy | Therapy with serum obtained from the patient's own blood. (05 Mar 2000) |
| aversion therapy | <psychology> A form of behaviour therapy that pairs an unpleasant stimulus with undesirable behaviour(s) so that the patient learns to avoid the latter. See: aversive training. (05 Mar 2000) |
| aversive therapy | <psychology> A treatment that suppresses undesirable behaviour by simultaneously exposing the subject to unpleasant consequences. (12 Dec 1998) |
Synonyms : DNA Therapy, Gene Therapy, Somatic, Therapy, DNA, Therapy, Gene, Therapy, Somatic Gene
| gene therapy |
Treatment that alters a gene. In studies of gene therapy for cancer, researchers are trying to improve the body's natural ability to fight the disease or to make the cancer cells more sensitive to other kinds of therapy.
Ãâó: www.stjude.org/glossary
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|---|---|
| gene therapy |
Any of a number of experimental treatments in which cell genes are altered. Some gene therapies attempt to provoke new immune activity; some try to render cells resistant to infection; and others involve the development of enzymes that destroy viral or cancerous genetic material within cells.
Ãâó: www.amfar.org/cgi-bin/iowa/bridge.html
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| gene therapy |
The correction of a genetic deficiency in a cell by the addition of new DNA and its insertion into the genome.
Ãâó: helios.bto.ed.ac.uk/bto/glossary/gh.htm
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| gene therapy |
Treatment of a disease caused by malfunction of a gene, by stably transfecting the cells of the organism with the normal gene.
Ãâó: virtualtrials.com/dictionary.cfm
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| gene therapy |
Treatment to modify the genes of a person's white blood cells or tumor cells to try to control or cure the cancer.
Ãâó: nydailynews.healthology.com/nydailynews/15836.htm
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