| 영문 | gene | 한글 | 유전자 |
|---|---|---|---|
| 설명 | 유전자는 길게 띠를 형성한 DNA분자의 일부분으로 한 가지 물질을 만드는데 필요한 모든 정보를 갖춘 기능적인 단위이다. 예를 들어 인슐린이라는 물질의 유전자라고 하면 사람의 세포내에 있는 긴 DNA 분자 중에서 인슐린이라는 물질을 만드는데 필요한 모든 정보를 가지고 있는 한 부분을 가리키는 말이다. 고전적인 생물학에서는 유전자가 표현형을 결정하거나 지정하는 염색체의 일부분이라고 정의되었지만, 오늘날에는 유전자에 대해서 분자적 정의가 제안되고 있으며 그 정의는 하나의 유전자는 하나의 효소를 결정 또는 암호화하는 유전물질의 일부분이라는 개념으로 이것이 이른바 1개의 유전자 1개 효소가설(one gene-one enzyme hypothesis)이다. 즉 1개의 유전자는 1개의 효소를 제작하는데 필요한 유전정보를 가진다는 것이다. 현재 이 가설이 받아들여지고 있다. |
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| 영문 | gene therapy | 한글 | 유전자요법 |
|---|---|---|---|
| 설명 | 유전병을 치료할 목적으로, 정상적으로 기능하는 단일유전자 혹은 복수유전자를 어떤 기원에서 얻어내어 생세포에 도입하는 것. 유전물질은 유전자삽입 조작에 의해 수용세포에로 도입된다. 즉, 유전자를 끼워 넣은 새로운 세포를 사용하는 치료로서 1980년 미국의 학자가 지중해빈혈환자에게 강행하여 비판을 받았지만, 미국 국립보건연구소는 1990년 9월 아데노신 데아미나아제(adenosine deaminase, ADA) 결핍증 환자의 림프구에 ADA 유전자를 끼워 넣는 치료를 시작한 이래 현재는 암을 포함한 많은 질병들을 치료하는 목적으로 쓰인다. |
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| CGRP | Calcitonin Gene Related Peptide(Protein) |
|---|---|
| CGRPs | Calcitonin Gene-Related Products |
| GnRH | Gonadotropin Releasing Hormone [HP 1898, 2034] = LHRH = Go... |
| ARGS | antitrypsin-related gene sequence |
| CAP | camptodactyly-arthropathy-pericarditis [syndrome]; Canada Assistance Plan; capsule; captopril; catab... |
| ESE | Exonic splicing enhancer |
|---|---|
| NRS | negative regulator of splicing |
| 16S rDNA | 16S rRNA gene |
| PGK | 3-phosphoglycerate kinase gene |
| CGRP | AM/calcitonin gene-related peptide |
| gene splicing | A procedure by which one DNA molecule or fragment can be attached to another. (14 Nov 1997) |
|---|
| acceptor splicing site | Boundary between the right end of an intron and the left end of the adjacent exon. Synonym: acceptor splicing site. (05 Mar 2000) |
|---|---|
| alternative mRNA splicing | Splicing different exons in or out of messenger RNA to form different mRNA transcripts. (09 Oct 1997) |
| alternative splicing | A process whereby multiple protein isoforms are generated from a single gene. Alternative splicing involves the splicing together of nonconsecutive exons during the processing of some, but not all, transcripts of the gene. Thus a particular exon may be connected to any one of several alternative exons to form messenger RNA. The alternative forms produce proteins in which one part is common while the other part is different. (12 Dec 1998) |
| right splicing junction | Boundary between the right end of an intron and the left end of the adjacent exon. Synonym: acceptor splicing site. (05 Mar 2000) |
| RNA splicing | <molecular biology> The removal of introns from primary RNA transcripts. (23 Aug 1998) |
| RNA splicing pattern | <molecular biology> The combination of DNA sequences copied from a gene by messenger RNA. The mRNAs transcribed from a single gene may splice together different parts of the sequence of the gene. (23 Aug 1998) |
| protein splicing | Excision of in-frame internal protein sequences (inteins) of a precursor protein, coupled with ligation of the flanking sequences (exteins). Protein splicing is an autocatalytic reaction and results in the production of two proteins from a single primary translation product: the intein and the mature protein. (12 Dec 1998) |
| self splicing | <molecular biology> Self catalysed removal of group 5 introns, mediated by six paired conserved regions. (18 Nov 1997) |
| splicing | <molecular biology> The process by which introns are removed from hnRNA to produce mature messenger RNA that contains only exons. Alternative splicing seems to occur in many proteins and by alternative exon usage a set of related proteins can be generated from one gene, often in a tissue or developmental stage specific manner. (18 Nov 1997) |
| splicing endonuclease | <enzyme> Cleaves intervening sequences of precursors trna, which are then joined by an RNA ligase Registry number: EC 3.1.27.- Synonym: pre-trna splicing endonuclease, trna splicing endonuclease, splicing endonuclease (xenopus), 3'-pre-trna endonuclease, trna-splicing endonuclease (26 Jun 1999) |
| intron splicing | The excision of mRNA fragments, which correspond to non-coding DNA introns, and the ligation of the remaining mRNA fragments to form a single molecule. (14 Nov 1997) |
| trans splicing | <molecular biology> Relating to RNA splicing of two different pre mRNA molecules together. Seems to rely on intron like sequences. Contrasts with the normal cis splicing of conventional RNA molecules. (19 Jan 1998) |
| trans-splicing | Formation of spliced products containing portions of two different transcripts. (05 Mar 2000) |
| tRNA splicing ligase | <enzyme> One of two enzymes involved in trna splicing in archaea Registry number: EC 6.5.1.- (26 Jun 1999) |
| allelic gene | See: allele, dominance of traits. (05 Mar 2000) |
| gene splicing |
The isolation of a gene from one organism and then the introduction of that gene into another organism using techniques of biotechnology.
출처: usinfo.state.gov/journals/ites/0903/ijee/glossary....
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|---|---|
| gene splicing |
Combining genes from different organisms into the chromosomes of one organism; also called recombinant DNA techniques.
출처: www.bdt.fat.org.br/binas/Library/ucs/section9.2.ht...
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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