| 영문 | gene | 한글 | 유전자 |
|---|---|---|---|
| 설명 | 유전자는 길게 띠를 형성한 DNA분자의 일부분으로 한 가지 물질을 만드는데 필요한 모든 정보를 갖춘 기능적인 단위이다. 예를 들어 인슐린이라는 물질의 유전자라고 하면 사람의 세포내에 있는 긴 DNA 분자 중에서 인슐린이라는 물질을 만드는데 필요한 모든 정보를 가지고 있는 한 부분을 가리키는 말이다. 고전적인 생물학에서는 유전자가 표현형을 결정하거나 지정하는 염색체의 일부분이라고 정의되었지만, 오늘날에는 유전자에 대해서 분자적 정의가 제안되고 있으며 그 정의는 하나의 유전자는 하나의 효소를 결정 또는 암호화하는 유전물질의 일부분이라는 개념으로 이것이 이른바 1개의 유전자 1개 효소가설(one gene-one enzyme hypothesis)이다. 즉 1개의 유전자는 1개의 효소를 제작하는데 필요한 유전정보를 가진다는 것이다. 현재 이 가설이 받아들여지고 있다. |
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| 영문 | gene therapy | 한글 | 유전자요법 |
|---|---|---|---|
| 설명 | 유전병을 치료할 목적으로, 정상적으로 기능하는 단일유전자 혹은 복수유전자를 어떤 기원에서 얻어내어 생세포에 도입하는 것. 유전물질은 유전자삽입 조작에 의해 수용세포에로 도입된다. 즉, 유전자를 끼워 넣은 새로운 세포를 사용하는 치료로서 1980년 미국의 학자가 지중해빈혈환자에게 강행하여 비판을 받았지만, 미국 국립보건연구소는 1990년 9월 아데노신 데아미나아제(adenosine deaminase, ADA) 결핍증 환자의 림프구에 ADA 유전자를 끼워 넣는 치료를 시작한 이래 현재는 암을 포함한 많은 질병들을 치료하는 목적으로 쓰인다. |
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| APR | abdominoperineal resection; absolute proximal reabsorption; acute phase reaction or reactant; amebic... |
|---|---|
| ARR | aortic root replacement |
| AVR | accelerated ventricular rhythm; antiviral regulator; aortic valve replacement |
| DIR | double isomorphous replacement |
| DRF | Daily Rating Form; daily replacement factor; Deafness Research Foundation; dose reduction factor |
| AVR | Aortic Valve Replacement |
|---|---|
| CRRT | Continuous Renal Replacement Therapy |
| CRRTs | Continuous renal replacement therapies |
| DVR | Double Valve Replacement |
| ERT | Enzyme replacement therapy |
| acetate replacement factor | <biochemistry> 1,2 dithiolane 3 valeric acid. Regarded as a coenzyme in the oxoglutarate dehydrogenase complex of the citric acid cycle. Involved generally in oxidative decarboxylations of _ keto acids. A growth factor for some organisms. (18 Nov 1997) |
|---|---|
| arthroplasty, replacement | Partial or total replacement of a joint. (12 Dec 1998) |
| arthroplasty, replacement, hip | Replacement of the hip joint. (12 Dec 1998) |
| arthroplasty, replacement, knee | Replacement of the knee joint. (12 Dec 1998) |
| renal replacement therapy | Procedures which temporarily or permanently remedy insufficient cleansing of body fluids by the kidneys. (12 Dec 1998) |
| replacement | 1. The act of replacing. 2. <chemistry> The removal of an edge or an angle by one or more planes. Source: Websters Dictionary (01 Mar 1998) |
| replacement bone | A bone that develops in a cartilage environment after the latter is partially or entirely destroyed by calcification and subsequent resorption. Synonym: cartilage bone, replacement bone. (05 Mar 2000) |
| replacement fibrosis | The formation of fibrous tissue that occupies sites where various other cells and tissues have become atrophied, or degenerated and necrotic. (05 Mar 2000) |
| replacement therapy | Therapy designed to compensate for a lack or deficiency arising from inadequate nutrition, from certain dysfunctions (e.g., glandular hyposecretion), or from losses (e.g., haemorrhage); replacement may be physiological or may entail administration of a substitute (e.g., a synthetic oestrogen in place of estradiol). (05 Mar 2000) |
| replacement vector | A cloning vector, such as a bacteriophage, in which some of the DNA of the vector can be replaced with foreign DNA. (09 Oct 1997) |
| hip replacement | Surgery to replace all or part of the hip joint with an artificial device that re-establishes normal hip joint motion. Indicated in cases of severe intractable degenerative arthritis (DJD). (27 Sep 1997) |
| hormone replacement therapy | In females, treatment with sex hormones for a number for reasons, including menopause, partial or full hysterectomy, or amenorrhoea.In women, treatment with sex hormones is indicated for a number of reasons, including menopause, partial or full hysterectomy, or amenorrhoea. After menopause, conjugated oestrogens, estradiol, or estrone sulfate are given to reduce pain during intercourse, limit blood vessel effects, and prevent loss of bone mass. After radical hysterectomy, conjugated oestrogens are given for similar reasons. After menopause or partial hysterectomy, progestin is administered at the same time to offset an increased risk of endometrial cancer. In some amenorrhoeas, oestrogen is given to restore menses; if the therapy is unsuccessful, this may indicate the presence of pathology, for instance, pituitary tumour. Benefits for postmenopausal women include a lowered risk of heart attack (oestrogen lowers LDL and raises HDL levels), and prevention of osteoporosis, since the rate of bone loss is directly linked to a drop in oestrogen levels (see perimenopause). Medical opinion about the hazard posed by such therapy remains divided. Some studies have indicated increased incidence of breast cancer; however, a comprehensive 1992 review of the literature contradicted this finding. (05 Mar 2000) |
| oestrogen replacement therapy | <endocrinology, gynaecology> The use of oestrogenic substances in postmenopausal or other oestrogen-deficient women to alleviate effects of hormone deficiency, such as vasomotor symptoms, dyspareunia, and progressive development of osteoporosis. (12 Dec 1998) |
| ossicular replacement | Surgical insertion of an implant to replace one or more of the ear ossicles. (12 Dec 1998) |
| total knee joint replacement | Surgery involving the replacement of the knee joint with artificial components which reestablishes normal joint function. Indicated in cases of severe knee fracture or degenerative arthritis (DJD) unresponsive to medical therapy. (27 Sep 1997) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|