| 영문 | gene | 한글 | 유전자 |
|---|---|---|---|
| 설명 | 유전자는 길게 띠를 형성한 DNA분자의 일부분으로 한 가지 물질을 만드는데 필요한 모든 정보를 갖춘 기능적인 단위이다. 예를 들어 인슐린이라는 물질의 유전자라고 하면 사람의 세포내에 있는 긴 DNA 분자 중에서 인슐린이라는 물질을 만드는데 필요한 모든 정보를 가지고 있는 한 부분을 가리키는 말이다. 고전적인 생물학에서는 유전자가 표현형을 결정하거나 지정하는 염색체의 일부분이라고 정의되었지만, 오늘날에는 유전자에 대해서 분자적 정의가 제안되고 있으며 그 정의는 하나의 유전자는 하나의 효소를 결정 또는 암호화하는 유전물질의 일부분이라는 개념으로 이것이 이른바 1개의 유전자 1개 효소가설(one gene-one enzyme hypothesis)이다. 즉 1개의 유전자는 1개의 효소를 제작하는데 필요한 유전정보를 가진다는 것이다. 현재 이 가설이 받아들여지고 있다. |
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| 영문 | gene therapy | 한글 | 유전자요법 |
|---|---|---|---|
| 설명 | 유전병을 치료할 목적으로, 정상적으로 기능하는 단일유전자 혹은 복수유전자를 어떤 기원에서 얻어내어 생세포에 도입하는 것. 유전물질은 유전자삽입 조작에 의해 수용세포에로 도입된다. 즉, 유전자를 끼워 넣은 새로운 세포를 사용하는 치료로서 1980년 미국의 학자가 지중해빈혈환자에게 강행하여 비판을 받았지만, 미국 국립보건연구소는 1990년 9월 아데노신 데아미나아제(adenosine deaminase, ADA) 결핍증 환자의 림프구에 ADA 유전자를 끼워 넣는 치료를 시작한 이래 현재는 암을 포함한 많은 질병들을 치료하는 목적으로 쓰인다. |
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| AAHSLD | Association of Academic Health Sciences Library Directors |
|---|---|
| ANSWER | Agency for Toxic Substances and Disease Registry/National Library of Medicine's Workstation for Emer... |
| BLLD | British Library Lending Division |
| BLOT | British Library of Tape |
| BLRC | Biomedical Library Review Committee |
| MLA | Medical Library Association |
|---|---|
| 16S rDNA | 16S rRNA gene |
| PGK | 3-phosphoglycerate kinase gene |
| CGRP | AM/calcitonin gene-related peptide |
| alpha-CGRP | Alpha calcitonin gene-related peptide |
| gene library | <molecular biology> A collection of cloned DNA fragments that contains all the genetic information of a particular organism. (09 Oct 1997) |
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| arrayed library | <molecular biology> Individual primary recombinant clones (hosted in phage, cosmid, YAC, or other vector) that are placed in two-dimensional arrays in microtiter dishes. Each primary clone can be identified by the identity of the plate and the clone location (row and column) on that plate. Arrayed libraries of clones can be used for many applications, including screening for a specific gene or genomic region of interest as well as for physical mapping. Information gathered on individual clones from various genetic linkage and physical map analyses is entered into a relational database and used to construct physical and genetic linkage maps simultaneously, clone identifiers serve to interrelate the multilevel maps. Compare: library, genomic library. (19 Jan 1998) |
|---|---|
| genomic library | <molecular biology> A collection of DNA molecules, derived from restriction fragments that have been cloned in vectors, that includes all or part of the genetic material of an organism. (18 Nov 1997) |
| cDNA library | <molecular biology> A collection of all of the mRNA molecules present in a cell or organism, all turned into cDNA molecules with the enzyme reverse transcriptase, then inserted into vectors (other DNA molecules which can continue to replicate after addition of foreign DNA). The library can then be probed for the specific cDNA (and thus mRNA) of interest. (09 Oct 1997) |
| peptide library | A collection of cloned free peptides, frequently consisting of all possible combinations of amino acids making up an n-amino acid peptide. (12 Dec 1998) |
| complementary DNA library | <molecular biology> A collection of all of the mRNA molecules present in a cell or organism, all turned into cDNA molecules with the enzyme reverse transcriptase, then inserted into vectors (other DNA molecules which can continue to replicate after addition of foreign DNA). The library can then be probed for the specific cDNA (and thus mRNA) of interest. (09 Oct 1997) |
| national library of medicine | An agency of the national institutes of health concerned with overall planning, promoting, and administering programs pertaining to various aspects of documentation and library services in the field of medicine. (12 Dec 1998) |
| DNA library | <molecular biology> A collection of DNA molecules, derived from restriction fragments that have been cloned in vectors, that includes all or part of the genetic material of an organism. (18 Nov 1997) |
| epitope library | <molecular biology> Large collection (hundreds of millions) of peptides each encoded by a randomly mutated piece of DNA in a phage genome and expressed on the surface of that bacteriophage, sometimes as an N terminal extension of a coat protein. Particular phages can be selected by a binding assay and since the peptide has its encoding DNA associated with it sequencing is straightforward. (18 Nov 1997) |
| expression library | <molecular biology> A library of DNA fragments which was created with an expression vector so that any genes present in the library are expressed. (09 Oct 1997) |
| library | <molecular biology> A collection of DNA molecules, derived from restriction fragments that have been cloned in vectors, that includes all or part of the genetic material of an organism. (18 Nov 1997) |
| library administration | Planning, organizing, staffing, direction, and control of libraries. (12 Dec 1998) |
| library, arrayed | In genetics, arrayed libraries of DNA clones are used for many purposes, including screening for a specific gene or genomic region of interest as well as for physical mapping. An arrayed library consists of (in technical terms) individual primary recombinant clones (which are hosted in phage, cosmid, yac, or another vector) that have been placed in two-dimensional arrays in microtiter dishes (plastic dishes with an orderly array of tiny wells). Each primary clone can be identified by the identity of the plate and the clone location (row and column) on that plate. The information gathered on individual clones from various genetic linkage and physical map analyses is then entered into a relational database and used to construct physical and genetic linkage maps. (12 Dec 1998) |
| library automation | The use of automatic machines or processing devices in libraries. The automation may be applied to library administrative activities, office procedures, and delivery of library services to users. (12 Dec 1998) |
| library collection development | Development of a library collection, including the determination and coordination of selection policy, assessment of needs of users and potential users, collection use studies, collection evaluation, identification of collection needs, selection of materials, planning for resource sharing, collection maintenance and weeding, and budgeting. (12 Dec 1998) |
| library, genomic | A collection of DNA clones made from a set of randomly generated overlapping DNA fragments representing the entire genome of an organism. As a molecular genetic sequel to john steinbeck's of mice and men , today you can have a mouse genomic library or a human genomic library. (12 Dec 1998) |
Synonyms : DNA Libraries, Gene Libraries, Libraries, DNA, Libraries, Gene, Libraries, cDNA, Library, DNA, Library, Gene, Library, cDNA, cDNA Libraries
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|