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  • gallium
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167Ga radioactive Gallium(used in whole-body & brain scans)
Ga gallium; granulocyte agglutination
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67Ga Gallium
Ga Gallium
GaAs Gallium arsenide
GA-67 Gallium-67
CancerWEB ¿µ¿µ ÀÇÇлçÀü À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
bone: gallium imaging <radiology> Increased activity in: active osteomyelitis (90% sensitivity: better than Tc-99m MDP), sarcoma, cellulitis, septic arthritis, rheumatoid arthritis, Paget disease, metastases (65% sensitivity: than for bone agents) see: gallium: indications
(12 Dec 1998)
gallium <chemistry, element> A rare metallic element, found in certain zinc ores. It is white, hard, and malleable, resembling aluminium, and remarcable for its low melting point (86 F, 30C).
The element was predicted with most of its properties, under the name ekaluminium, by the Russian chemist Mendelejeff, on the basis of the Periodic law. This prediction was verified in its discovery by the French chemist Lecoq de Boisbaudran by its characteristic spectrum (two violet lines), in an examination of a zinc blende from the Pyrenees.
Atomic weight: 69.9
Abbreviation: Ga
Origin: NL, fr. L. Gallia France.
Source: Websters Dictionary
(01 Mar 1998)
gallium-67 A cyclotron-produced radionuclide with a half-life of 3.260 days and major gamma ray emissions of 93, 185, and 300 kiloelectron volts; used in the citrate form as a tumour-and inflammation-localizing radiotracer.
(05 Mar 2000)
gallium-67 citrate <radiology> Analogue of ferric iron, decay: by electron capture to ground state of Zn-67, energy levels: 92 KeV (40%); 184 KeV (23%); 296 KeV (21%), physiological half life: 3.3 days (78 hr), biological half life: 2-3 weeks, binding sites: serum: transferrin, haptoglobin, albumin, globulins, tissue: lactoferrin, PMN's (viable and nonviable), lymphocytes, macrophages, bacteria and fungi, tumour cell-associated transferrin receptor see: gallium: indications
(12 Dec 1998)
gallium-68 A positron emitter with a radioactive half-life of 1.130 hours.
(05 Mar 2000)
gallium: indications <radiology> Indications: inflammation, bone, tumour, lung, renal, lymphoma, malignant melanoma NO UPTAKE: most benign neoplasms, haemangioma, cirrhosis, cystic disease of breast, liver, thyroid, reactive lymphadenopathy, inactive granulomatous disease see: gallium-67 citrate
(12 Dec 1998)
gallium isotopes Stable gallium atoms that have the same atomic number as the element gallium, but differ in atomic weight. Ga-71 is a stable gallium isotope.
(12 Dec 1998)
gallium radioisotopes Unstable isotopes of gallium that decay or disintegrate emitting radiation. Ga atoms with atomic weights 63-68, 70 and 72-76 are radioactive gallium isotopes.
(12 Dec 1998)
gallium uptake with normal chest film <radiology> Pulmonary drug toxicity, tumour infiltration, sarcoidosis, pneumocystis carinii see: lung: gallium imaging
(12 Dec 1998)
gallium vs. indium <radiology> Advantages: Ga-67 citrate, readily available, no preparation, bone and soft-tissue infections, chronic inflammatory processes, In-111 WBCs, no bowel uptake, minimal or no uptake in healing wounds, images easier to interpret, high specificity for inflammatory process
(12 Dec 1998)
malignant melanoma: gallium imaging <radiology> Greater than50% sensitivity for primary and metastatic sites: 73% sensitivity if lesion is greater than 2 cm, 17% sensitivity if less than 2 cm, see: gallium: indications malignant melanoma
(12 Dec 1998)
neoplasm: gallium imaging <radiology> Useful: Hodgkin disease and histiocytic form of NHL poor sensitivity below the diaphragm, Burkitt lymphoma: almost 100% sensitivity, hepatoma: 90% sensitivity, melanoma: 90% sensitivity, leukaemia possibly useful: NHL: good for large and mediastinal lesions, nodal metastases from seminoma and embryonal cell carcinoma: 87% sensitivity, non-small cell lung CA: 85% sensitive not useful: head and neck, GI (especially adenocarcinoma), breast, gynaecological, kiddie tumours see: gallium: indications
(12 Dec 1998)
inflammation: gallium imaging <radiology> Pathophysiology: leakage of protein-bound Ga-67 into extracellular space secondary to increased capillary permeability, Ga-67 is preferentially bound to nonviable PMNs and macrophages, leukocyte incorporation (rich in lactoferrin), bacterial uptake (siderophores), inflammtory tissue stimulates lactoferrin production for chronic abdominal inflammation: 67% sensitivity; 64% specificity; 13% false negatives; 5% false positive, dose: 5 mCi; imaging: 24, 48, 72 hours, diffuse uptake in peritonitis, localised uptake in acute pyogenic abscess, phlegmon, acute cholecystitis, acute pancreatitis, acute gastritis, diverticulitis, inflammatory bowel disease, surgical wound, pyelonephritis, perinephric abscess see: gallium indications, gallium vs. Indium
(12 Dec 1998)
kidney: gallium imaging <radiology> 10-20% of Ga-67 excreted via GU tract; no renal activity after 24hrs abnormal uptake (images at 48-72 hrs): tumour, primary renal tumour (variable uptake), lymphoma/leukaemia, metastases (e.g., melanoma), inflammation, acute pyelonephritis (88% sensitivity); abscess, lobar nephroma, others, collagen vascular disease, vasculitis, Wegener granulomatosis, amyloidosis, haemochromatosis, hepatic failure, antineoplastic drugs, transplant rejection: acute, chronic, ATN see also: gallium: indications
(12 Dec 1998)
lung: gallium imaging <radiology> Scans at 48 hrs because 50% of normals show activity at 24 hrs, focal uptake, primary pulmonary malignancy, benign disorder: granuloma, abscess, pneumonia, silicosis, multifocal/diffuse uptake, infection, TB: active lesion, miliary TB, rapidly progressive TB pneumonia, PCP: unimpressive symptoms and CXR, CMV, inflammation: sarcoid, interstitial lung disease (pneumoconiosis, idiopathic pulmonary fibrosis, lymphangitic carcinomatosis), radiation pneumonitis, drugs: bleomycin, amiodarone, contrast lymphangiography (in 50%) see: gallium: indications, uptake with normal chest film
(12 Dec 1998)
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