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| HFI | hereditary fructose intolerance; human fibroblast interferon |
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| AMI | acquired monosaccharide intolerance; acute myocardial infarction; amitriptyline; anterior myocardial... |
| ASA | acetylsalicylic acid; active systemic anaphylaxis; Adams-Stokes attack; American Society of Anesthes... |
| FCI | fixed-cell immunofluorescence; food chemical intolerance |
| FI | fasciculus intrafascicularis; fever caused by infection; fibrinogen; fixed interval; flame ionizatio... |
| HFI | Hereditary Fructose Intolerance |
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| CMPI | Cow's Milk Protein Intolerance |
| LPI | Lysinuric protein intolerance |
| OI | Orthostatic Intolerance |
| PFK-2/FBPase-2 | 6-Phosphofructo-2-kinase/fructose 2,6-bisphosphatase |
| fructose intolerance | An autosomal recessive fructose metabolism disorder due to deficient fructose-1-phosphate aldolase (ec 2.1.2.13) activity, resulting in accumulation of fructose-1-phosphate. The accumulated fructose-1-phosphate inhibits glycogenolysis and gluconeogenesis, causing severe hypoglycaemia following ingestion of fructose. Prolonged fructose ingestion in infants leads ultimately to hepatic failure and death. Patients develop a strong distaste for sweet food, and avoid a chronic course of the disease by remaining on a fructose- and sucrose-free diet. (12 Dec 1998) |
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| hereditary fructose intolerance | A metabolic error due to deficiency of hepatic fructose 1,6-bisphosphate aldolase B (which also acts on fructose 1-phosphate); the second enzyme in the specific fructose pathway; vomiting and hypoglycaemia follow ingestion of fructose; prolonged fructose ingestion in young children results in failure to thrive and in jaundice, hepatomegaly, albuminuria, aminoaciduria, and sometimes cachexia and death; autosomal recessive inheritance in most families. (05 Mar 2000) |
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| fructose-6-phosphate,2-kinase-fructose-2,6-bisphosphatase | <chemical> From rat skeletal muscle and liver; catalyses the synthesis and degradation of fructose 2,6-bisphosphate; contains EC 2.7.1.105 and EC 3.1.3.46 Synonym: fru-kinase-fru-bisphosphatase, f kinase-f-bisphosphatase, 6-phosphofructo 2-kinase-fructose 2,6-bisphosphatase, 6-pf-2-k-fru-2,6-p(2)ase (26 Jun 1999) |
| glucose intolerance | A pathological state in which the fasting plasma glucose level is less than 140 mg per deciliter and the 30-, 60-, or 90-minute plasma glucose concentration following a glucose tolerance test exceeds 200 mg per deciliter. This condition is seen frequently in diabetes mellitus but also occurs with other diseases. (12 Dec 1998) |
| intolerance | Inability to withstand, sensitivity, as to a drug. Origin: L. Tolerare = to bear (18 Nov 1997) |
| lactose intolerance | A disorder characterised by abdominal cramps and diarrhoea after the consumption of food containing lactose (for example milk, ice cream), believed to occur due to a deficiency of intestinal lactase (enzyme that breaks down lactose), may appear first in young adults who have previously tolerated milk well as infants. (27 Sep 1997) |
| lysinuric protein intolerance | An autosomal recessive disorder characterised by elevated levels of dibasic amino acids (e.g., l-lysine, l-arginine, and l-ornithine) in the urine; apparently due to a defect in dibasic amino acid transport. (05 Mar 2000) |
| glucose-1-fructose-2-oxidoreductase | <enzyme> Catalyses intermolecular oxidation-reduction of glucose and fructose to form gluconolactone and sorbitol; contains tightly bound nadp as h+ carrier; does not require added cofactor Registry number: EC 1.1.1.- (26 Jun 1999) |
| glucose-fructose oxidoreductase | <enzyme> Isolated from zymomonas mobilis; catalyses the formation of sorbitol and glucono-delta-lactone from glucose and fructose; enzyme contains tightly bound nadp+ Registry number: EC 1.1.99.- (26 Jun 1999) |
| glutamine-fructose-6-phosphate transaminase (isomerizing) | <enzyme> An enzyme that catalyses the synthesis of fructose-6-phosphate plus glutamine from glutamate plus glucosamine-6-phosphate. Chemical name: L-Glutamine:D-fructose-6-phosphate aminotransferase (hexose-isomerizing) Registry number: EC 2.6.1.16 (12 Dec 1998) |
| D-fructose 5-dehydrogenase | <enzyme> Catalyses the oxidation of fructose with any acceptor to 5-ketofructose and reduced acceptor Registry number: EC 1.1.99.11 (26 Jun 1999) |
| ferric fructose | A potassium-iron-fructose; a haematinic drug. (05 Mar 2000) |
| 6-phosphofructo-2-kinase-fructose-2,6-bisphosphatase | <chemical> Hepatic bifunctional enzyme that both degrades and synthesises fructose-2,6-bisphosphate Synonym: 6pf-2-k-fru-2,6-p(2)ase, hepatic 6-phosphofructo-2-kinase, hepatic fructose-2,6-bisphosphatase, pfk-2 (liver), pbpase-2 (liver) (26 Jun 1999) |
| fructose | <biochemistry> A 6 carbon sugar (hexose) abundant in plants. Fructose has its reducing group (carbonyl) at C2 and thus is a ketose, in contrast to glucose that has its carbonyl at C1 and thus an aldose. Sucrose, common table sugar, is the nonreducing disaccharide formed by an alpha linkage from C1 of glucose to C2 of fructose (latter in furanose form). Fructose is a component of polysaccharides such as inulin, levan. (18 Nov 1997) |
| fructose 1,6-bisphosphate | <biochemistry> This key intermediate in glycolysis and gluconeogenesis (a hexose diphosphate) was discovered by Arthur Harden and William Young in 1905. In the third step of glycolysis, fructose 6-phosphate and ATP are converted to fructose 1,6-bisphosphate and ADP with the aid of phosphofructokinase. In step 4, fructose 1,6 bisphosphate (with the aid of aldolase) is cleaved into duhydroxyacetone phosphate and glyceraldehyde 3-phosphate. Synonym: hexosebisphosphatase, hexosediphosphatase. (08 Mar 2000) |
| fructose-1,6-diphosphatase deficiency | An autosomal recessive fructose metabolism disorder due to absent or deficient fructose-1,6-diphosphatase activity. Gluconeogenesis is impaired, resulting in accumulation of gluconeogenic precursors (e.g., amino acids, lactate, ketones) and manifested as hypoglycaemia, ketosis, and lactic acidosis. Episodes in the newborn infant are often lethal. Later episodes are often brought on by fasting and febrile infections. As patients age through early childhood, tolerance to fasting improves and development becomes normal. (12 Dec 1998) |
Synonyms : Fructose Intolerances, Intolerance, Fructose, Intolerances, Fructose
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