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| ¿µ¹® | ion | ÇÑ±Û | À̿ |
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| g-ion | gram-ion |
|---|---|
| ISS | idiopathic short stature; injury severity score; International Society of Surgery; ion-scattering sp... |
| RFLPs | Restriction Fragment Length Polymorphisms; Á¦ÇÑÈ¿¼Ò´ÜÆíÀå´ÙÇü |
| UGF | Urinary Gonadotropin Fragment |
| B3F | band 3 cytoplasmic fragment |
| AFLP | Amplified Fragment Length Polymorphism |
|---|---|
| CTF | C-terminal fragment |
| FAFLP | Fluorescent Amplified Fragment Length Polymorphism |
| HTF | Hpa II tiny fragment |
| KF | Klenow fragment |
| acentric fragment | A fragment of a chromosome lacking a centromere and unable to attach to the mitotic spindle, therefore unable to take part in the division of a nucleus and randomly distributed in daughter cells. Synonym: acentric fragment. (05 Mar 2000) |
|---|---|
| amplified fragment length polymorphism | <technique> Invented by KeyGene, a Dutch biotech company based in Wageningen, Holland. The technique is now merchandised under licence agreement by Perkin Elmer. Selected markers are amplified in a PCR, which makes amplified fragment length polymorphism an easy and fast tool for strain identification in agriculture, botany, microbiology and animal breeding. Acronym: AFLP (05 Feb 1998) |
| Brimacombe fragment | A ribonucleoprotein fragment obtained by mild ribonuclease treatment of ribosomes. (05 Mar 2000) |
| butterfly fragment | A broad triangular fragment that is commonly present in comminuted fractures of the diaphysis. (05 Mar 2000) |
| restriction fragment | <molecular biology> The fragments of DNA generated by digesting DNA with a specific restriction endonuclease. Each of the fragments ends in a site recognised by that specific enzyme. (10 Mar 1998) |
| restriction fragment length polymorphism | <molecular biology, technique> A method that allows familial relationships to be established by comparing the characteristic polymorphic patterns that are obtained when certain regions of genomic DNA are amplified (typically by PCR) and cut with certain restriction enzymes. The variation in the length of DNA fragments produced by a restriction endonuclease that cuts at a polymorphic locus. Such variations are generated by mutations that create or abolish recognition sites for these enzymes. This is a key tool in DNA fingerprinting, reflecting the existence of different alleles in the individual. Restriction fragment length polymorphism mapping is also used in plant breeding to see if a key trait such as disease resistance is inherited. In principle, an individual can be identified unambiquously by restriction fragment length polymorphism hence the use of restriction fragment length polymorphism in forensic analysis of blood, hair or semen). Similarly, if a polymorphism can be identified close to the locus of a genetic defect, it provides a valuable marker for tracing the inheritance of the defect. Synonym: DNA fingerprinting. Acronym: RFLP (12 Jan 1998) |
| Okazaki fragment | A relatively short (100-1000 bp) fragment of DNA that is later joined by DNA ligase to allow for 3' → 5' overall chain growth during replication. (05 Mar 2000) |
| one-carbon fragment | The formyl group or the methyl group that takes part in transformylation or transmethylation reactions; by means of these reactions, a group containing a single carbon atom is added to a compound being biosynthesised, adding a methyl group (as in thymidine formation), adding a hydroxymethyl group (as in serine biosynthesis), or closing a ring (as in purine formation). (05 Mar 2000) |
| two-carbon fragment | The acetyl group (CH3CO-) that takes part in transacetylation reactions with coenzyme A as carrier; commonly referred to as acetate or acetic acid, from which it is derived. (05 Mar 2000) |
| f2 fragment | <immunology> A fragment of an antibody protein which includes the antigen-binding portions but not the Fc section. They can be produced by treating whole antibodies with proteases that will specifically cleave off the Fc section. (09 Oct 1997) |
| Fab fragment | The antigen-binding fragment of an immunoglobulin molecule, consisting of both a light chain and part of a heavy chain. Synonym: Fab piece. (05 Mar 2000) |
| Fc fragment | <immunology> The constant region on an immunoglobulin molecule. The area that is exactly the same on all antibodies. The region is found on the heavy chains and is not involved in binding antigens. (09 Oct 1997) |
| Klenow fragment | <molecular biology> Larger part of the bacterial DNA polymerase I (76 kD) that remains after treatment with subtilisin, retains some but not all exonuclease and polymerase activity. (18 Nov 1997) |
| fragment | A small part broken from a larger entity. (05 Mar 2000) |
| fragment reaction | A reaction used to assay the activity of peptidyl transferase. (05 Mar 2000) |
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