| formiminoglutamic acid | <chemical> 2-(formylazo)glutaric acid. Measurement of this acid in the urine after oral administration of histidine provides the basis for the diagnostic test of folic acid deficiency and of megaloblastic anaemia of pregnancy. Chemical name: L-Glutamic acid, N-(iminomethyl)- (12 Dec 1998) |
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| formiminotetrahydrofolate cyclodeaminase | <enzyme> Formiminotransferase catalyses reaction of formiminoglutamate + tetrahydrofolate giving formiminotetrahydrofolate + glutamate; copurifies with the cyclodeaminase Registry number: EC 4.3.1.4 Synonym: formiminotransferase-cyclodeaminase (26 Jun 1999) |
Synonyms : Acid, Formiminoglutamic
| formimino |
the group —CH=NH.
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| formiminoglutamate |
the anionic form of formiminoglutamic acid.
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| formiminoglutamic acid |
an intermediate in the catabolic pathway from histidine to glutamate. It may be excreted in the urine in liver disease, in vitamin B12 or folic acid deficiency, or in glutamate formiminotransferase deficiency. Abbreviated FIGLU.
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| formiminotetrahydrofolate cyclodeaminase |
[EC 4.3.1.4] an enzyme of the lyase class that catalyzes the deamination of 5-formiminotetrahydrofolate to form 5,10-methenyltetrahydrofolate, a step in the degradation of histidine. The enzyme activity occurs in a bifunctional enzyme, along with glutamate formiminotransferase (q.v.) activity.
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| formiminotransferase |
any enzyme that transfers a formimino group; usually used to refer to glutamate formiminotransferase.
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