| ¿µ¹® | cephalosporin | ÇÑ±Û | ¼¼ÆÈ·Î½ºÆ÷¸° |
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| CEPH | cephalic; cephalosporin; Council on Education for Public Health |
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| cephalosporin | <drug> A large class of antibiotics similar both chemically and in their mode of action to penicillin's. They are tetracyclic triterpene broad-spectrum antibiotics first isolated from the culture filtrates of mediterranean fungus acremonium (cephalosporium acremonium). They contain the beta-lactam moiety thia-azabicyclo-octenecarboxylic acid also called 7-aminocephalosporanic acid and are effective against gram-positive bacteria. Examples include: Keflex, Ceftin, Rocephin, Cefzil, Monocid, Keftab, Vantin, Ceclor, Duricef, Suprax and Cefobid. (25 Jun 1999) |
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| cephalosporin 7-alpha-hydroxylase | <enzyme> A dioxygenase from streptomyces clavuligerus; requires 2-oxoglutarate, fe2+ and a reducing agent such as ascorbic acid Registry number: EC 1.14.11.- (26 Jun 1999) |
| cephalosporin C transaminase | <enzyme> Acts on cephalosporin c and a number of d-amino acids; alpha-ketoadipic and alpha-ketoglutaric acids act as acceptors Registry number: EC 2.6.1.- (26 Jun 1999) |
| cephalosporin resistance | <microbiology> Non-susceptibility of an organism to the action of the cephalosporins. (12 Dec 1998) |
| first-generation cephalosporins |
Group of cephalosporin antibiotics capable of killing gram-positive cocci such as Staphylococcus aureus, streptococci, and some aerobic gram-negative rods. These agents are commonly used to treat skin and s
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