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  • Fibroblast growth factor
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  • Fibroblasts
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  • fibroblast growth factor
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  • fibroblast growth factor(FGF)
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  • chick embryo fibroblast
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CF calcaneal fibular [ligament]; calcium leucovorin; calf blood flow; calibration factor; cancer-free; ...
GSF galactosemic fibroblast; genital skin fibroblast
HEF hamster embryo fibroblast; human embryo fibroblast
aFGF acidic fibroblast growth factor
bFGF basic fibroblast growth factor
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aFGF Acidic Fibroblast Growth Factor
bFGF Basic Fibroblast Growth Factor
bFGF/FGF2 Basic Fibroblast Growth Factor
basic FGF Basic fibroblast growth factor
FGF C--fibroblast growth factor
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  • fibroblastic
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fibroblast <pathology> Resident cell of connective tissue, mesodermally derived, that secretes fibrillar procollagen, fibronectin and collagenase.
(18 Nov 1997)
fibroblast growth factor <growth factor> Acidic fibroblast growth factor (alpha FGF, HBGF 1) and basic FGF (beta FGF, HBGF 2) are the two founder members of a family of structurally related growth factors for mesodermal or neuroectodermal cells.
Synonym: heparin binding growth factor.
Acronym: FGF
(18 Nov 1997)
fibroblast growth factor receptor Family of receptor tyrosine kinases for fibroblast growth factor.
(18 Nov 1997)
fibroblast growth factor receptor-like embryonic kinase <enzyme> Found in avian embryonic tissue; involved in early differentiation of skeletal muscle.
Registry number: EC 2.7.1.-
Synonym: frek
(26 Jun 1999)
fibroblast growth factor, acidic <chemical> A growth factor which has been isolated from a variety of cells. It contains 154 amino acid residues and has potent heparin-binding activity. Heparin potentiates the biological activities of afgf. The growth factor is an extremely potent inducer of DNA synthesis in a variety of normal diploid mammalian cell types from mesoderm and neuroectoderm lineages and also has chemotactic and mitogenic activities.
Chemical name: Fibroblast growth factor (human brain acidic protein moiety reduced)
(12 Dec 1998)
fibroblast growth factor, basic A single-chain polypeptide of approximately 15-16 kD which has been isolated from a variety of cells. It has a 55% amino acid residue identity to acidic fibroblast growth factor and has potent heparin-binding activity. However, in contrast to the acidic fibroblast growth factor, heparin does not potentiate the biological activities of bfgf. The growth factor is an extremely potent inducer of DNA synthesis in a variety of normal diploid mammalian cell types from mesoderm and neuroectoderm lineages and promotes cellular differentiation in vitro.
(12 Dec 1998)
fibroblast interferon <cytokine> One of the type I interferons produced by fibroblasts in response to stimulation by live or inactivated virus or by double-stranded RNA. It is a cytokine with antiviral, antiproliferative, and immunomodulating activity.
Synonym: fibroblast interferon.
Pharmacological action: adjuvants, immunologic, antineoplastic agent, antiviral agents.
Chemical name: Interferon-alphaB (human leukocyte protein moiety reduced)
(12 Dec 1998)
fibroblastic <pathology> Many types of cultured cell become fibroblastic in appearance this does not mean that they are fibroblasts.
(18 Nov 1997)
fibroblasts Connective tissue cells which differentiate into chondroblasts, collagenoblasts, and osteoblasts.
(12 Dec 1998)
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receptors, fibroblast growth factor Specific molecular sites or structures on cell membranes that react with fibroblast growth factors (both the basic and acidic forms), their analogs, or their antagonists to elicit or to inhibit the specific response of the cell to these factors. These receptors frequently possess tyrosine kinase activity.
(12 Dec 1998)
chick heart fibroblast <cell culture> The cells that emigrate from an explant of embryonic chick heart maintained in culture. Often used as archetypal normal cell.
(05 Jan 1998)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 5 ÆäÀÌÁö: 1
  • Fibroblast Growth Factor 1 - »õâ A 17-kDa single-chain polypeptide growth factor that plays a significant role in the process of WOUND HEALING and is a potent inducer of PHYSIOLOGIC ANGIOGENESIS. It binds to HEPARIN, which potentiates its biological activity and protects it from proteolysis. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages, and also has chemotactic and mitogenic activities. It was originally named acidic fibroblast growth factor based upon its chemical properties and to distinguish it from basic fibroblast growth factor (FIBROBLAST GROWTH FACTOR 2).
    Synonyms : FGF-1, FGF1, Fibroblast Growth Factor-1, Heparin Binding Growth Factor, Class I
  • Fibroblast Growth Factor 10 - »õâ A fibroblast growth factor that is a mitogen for KERATINOCYTES. It activates FIBROBLAST GROWTH FACTOR RECEPTOR 2B and is involved in LUNG and limb development.
    Synonyms : Keratinocyte Growth Factor 2, Repifermin
  • Fibroblast Growth Factor 2 - »õâ A single-chain polypeptide growth factor that plays a significant role in the process of WOUND HEALING and is a potent inducer of PHYSIOLOGIC ANGIOGENESIS. Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative start sites within the fgf-2 gene. It has a 55 percent amino acid residue identity to FIBROBLAST GROWTH FACTOR 1 and has potent heparin-binding activity. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages. It was originally named basic fibroblast growth factor based upon its chemical properties and to distinguish it from acidic fibroblast growth factor (FIBROBLAST GROWTH FACTOR 1).
    Synonyms : Cartilage-Derived Growth Factor, Class II Heparin-Binding Growth Factor, FGF-2, FGF2, Fibroblast Growth Factor-2, Heparin-Binding Growth Factor Class II, Prostate Epithelial Cell Growth Factor, Prostatropin, Cartilage Derived Growth Factor, FGF 2
  • Fibroblast Growth Factor 3 - »õâ A fibroblast growth factor that is expressed primarily during development.
    Synonyms :
  • Fibroblast Growth Factor 4 - »õâ A HEPARIN binding fibroblast growth factor that may play a role in LIMB BUD development.
    Synonyms : Heparin Secretory Transforming Protein-1, Kaposi's Sarcoma Fibroblast Growth Factor, Proto-Oncogene Protein Hst-1, Proto-Oncogene Protein kfgf, Heparin Secretory Transforming Protein 1, Hst-1, Proto-Oncogene Protein, Proto Oncogene Protein Hst 1
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fibroblast a cell from which connective tissue develops
Ãâó: wordnet.princeton.edu/perl/webwn
fibroblast A connective tissue cell that makes and secretes collagen proteins.
Ãâó: www.stjude.org/glossary
fibroblast A large, flat cell that secretes most of the matrix (extracellular) material of the areolar and dense connective tissues.
Ãâó: www.nutrabio.com/Definitions/definitions_f.htm
fibroblast A term applied to a cell of connective tissue that is separated from similar cells by some degree of matrix material; fibroblasts secrete elastin and collagen protein fibers. PICTURE
Ãâó: www.emc.maricopa.edu/faculty/farabee/BIOBK/BioBook...
fibroblast growth factor Belongs to the FGF family of proteins that are involved in proliferation and differentiation of several cell types. It binds to receptors belonging to the tyrosine kinase family.
Ãâó: www.jco.org/cgi/glossarylookup
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fibroblast a cell from which connective tissue develops
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