| 영문 | gene | 한글 | 유전자 |
|---|---|---|---|
| 설명 | 유전자는 길게 띠를 형성한 DNA분자의 일부분으로 한 가지 물질을 만드는데 필요한 모든 정보를 갖춘 기능적인 단위이다. 예를 들어 인슐린이라는 물질의 유전자라고 하면 사람의 세포내에 있는 긴 DNA 분자 중에서 인슐린이라는 물질을 만드는데 필요한 모든 정보를 가지고 있는 한 부분을 가리키는 말이다. 고전적인 생물학에서는 유전자가 표현형을 결정하거나 지정하는 염색체의 일부분이라고 정의되었지만, 오늘날에는 유전자에 대해서 분자적 정의가 제안되고 있으며 그 정의는 하나의 유전자는 하나의 효소를 결정 또는 암호화하는 유전물질의 일부분이라는 개념으로 이것이 이른바 1개의 유전자 1개 효소가설(one gene-one enzyme hypothesis)이다. 즉 1개의 유전자는 1개의 효소를 제작하는데 필요한 유전정보를 가진다는 것이다. 현재 이 가설이 받아들여지고 있다. |
||
| 영문 | gene therapy | 한글 | 유전자요법 |
|---|---|---|---|
| 설명 | 유전병을 치료할 목적으로, 정상적으로 기능하는 단일유전자 혹은 복수유전자를 어떤 기원에서 얻어내어 생세포에 도입하는 것. 유전물질은 유전자삽입 조작에 의해 수용세포에로 도입된다. 즉, 유전자를 끼워 넣은 새로운 세포를 사용하는 치료로서 1980년 미국의 학자가 지중해빈혈환자에게 강행하여 비판을 받았지만, 미국 국립보건연구소는 1990년 9월 아데노신 데아미나아제(adenosine deaminase, ADA) 결핍증 환자의 림프구에 ADA 유전자를 끼워 넣는 치료를 시작한 이래 현재는 암을 포함한 많은 질병들을 치료하는 목적으로 쓰인다. |
||
| IVET | in vivo expression technology |
|---|---|
| NGBE | neuraminidase/beta-galactosidase expression |
| CGRP | Calcitonin Gene Related Peptide(Protein) |
| CGRPs | Calcitonin Gene-Related Products |
| GnRH | Gonadotropin Releasing Hormone [HP 1898, 2034] = LHRH = Go... |
| ESAG | expression site-associated gene |
|---|---|
| SAGE | Serial Analysis of Gene Expression |
| BEVS | Baculovirus Expression Vector System |
| IVET | In vivo expression technology |
| STAXI | State Trait Anger Expression Inventory |
| expression, gene | A gene speaks. When a gene is expressed, the information encoded in the gene is translated into protein or RNA structures present and operating in the cell. Expressed genes include genes that are transcribed into messenger RNA (mRNA) and then translated into protein as well as those genes that are transcribed into RNA (such transfer and ribosomal RNAs) but not translated into protein. (12 Dec 1998) |
|---|
| gene expression | <molecular biology> The full use of the information in a gene via transcription and translation leading to production of a protein and hence the appearance of the phenotype determined by that gene. Gene expression is assumed to be controlled at various points in the sequence leading to protein synthesis and this control is thought to be the major determinant of cellular differentiation in eukaryotes. (18 Nov 1997) |
|---|---|
| gene expression regulation | Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action at the level of transcription or translation. These processes include gene activation and genetic induction. (12 Dec 1998) |
| gene expression regulation, archaeal | Any of the processes by which cytoplasmic or intercellular factors influence the differential control of gene action in archaea. (12 Dec 1998) |
| gene expression regulation, bacterial | Any of the processes by which cytoplasmic or intercellular factors influence the differential control of gene action in bacteria. (12 Dec 1998) |
| gene expression regulation, developmental | Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action during the developmental stages of an organism. (12 Dec 1998) |
| gene expression regulation, enzymologic | Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in enzyme synthesis. (12 Dec 1998) |
| gene expression regulation, fungal | Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in fungi. (12 Dec 1998) |
| gene expression regulation, leukaemic | Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in leukaemia. (12 Dec 1998) |
| gene expression regulation, neoplastic | Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in neoplastic tissue. (12 Dec 1998) |
| gene expression regulation, plant | Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in plants. (12 Dec 1998) |
| gene expression regulation, viral | Any of the processes by which cytoplasmic factors influence the differential control of gene action in viruses. (12 Dec 1998) |
| differential gene expression | Gene expression that responds to signals or triggers; a means of gene regulation; e.g., effects of certain hormones on protein biosynthesis. (05 Mar 2000) |
| ambisense expression strategy | <molecular biology> The coding of viral proteins in both the sense (coding) and antisense (noncoding) strands of complementary mRNA, so that the viral proteins are produced no matter which strand gets translated. (09 Oct 1997) |
| mammalian expression vector | <molecular biology> A vector that will produce large amounts of eukaryotic protein taxonomy notwithstanding, and not necessarily a protein from a mammal. (20 Mar 1998) |
| muscles of facial expression | The numerous muscles supplied by the facial nerve that are attached to and move the skin of the face. Nomina Anatomica also includes the buccinator muscle in this group; even though it functions primarily in mastication. Synonym: musculi faciales, facial muscles, mimetic muscles. (05 Mar 2000) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|