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estrodienol <chemical> 4,4'-(1,2-diethylidene-1,2-ethanediyl)bisphenol. A synthetic, non-steroidal oestrogen structurally related to stilbestrol. It is used, usually as the cream, in the treatment of menopausal and postmenopausal symptoms.
Pharmacological action: oestrogens, non-steroidal.
Chemical name: Phenol, 4,4'-(1,2-diethylidene-1,2-ethanediyl)bis-
(12 Dec 1998)
estrogen <endocrinology, hormone> A generic term for oestrus producing steroid compounds, the female sex hormones.
In humans, oestrogen is formed in the ovary, possibly the adrenal cortex, the testis and the foetoplacental unit, it has various functions in both sexes. It is responsible for the development of the female secondary sex characteristics and during the menstrual cycle it acts on the female genitalia to produce an environment suitable for the fertilization, implantation and nutrition of the early embryo.
Oestrogen is used in oral contraceptives and as a palliative in cancer of the breast after menopause and cancer of the prostate, other uses include the relief of the discomforts of menopause, inhibition of lactation and treatment of osteoporosis, threatened abortion and various functional ovarian disorders.
(18 Nov 1997)
estrogen 2-hydroxylase <enzyme> Same enzyme for hydroxylation in 2 or 4 position
Registry number: EC 1.14.99.-
Synonym: estrogen 4-hydroxylase, ethinylestradiol 2-hydroxylase
(26 Jun 1999)
estrone <chemical> 3-hydroxyestra-1,3,5(10)-trien-17-one. A metabolite of estradiol but possessing less biological activity. It is found in the urine of pregnant women and mares, in the human placenta, and in the urine of bulls and stallions. According to the fourth annual report on carcinogens (ntp 85-002, 1985), estrone may reasonably be anticipated to be a carcinogen (merck, 11th ed).
Chemical name: Estra-1,3,5(10)-trien-17-one, 3-hydroxy-
(12 Dec 1998)
estrone reductase <enzyme> Enzyme from porcine endometrium catalyses NADPH-dependent reduction of estrone to estradiol; is not the reverse reaction for estradiol dehydrogenase from this source
Registry number: EC 1.1.1.-
(26 Jun 1999)
estrone unit The oestrogenic activity of 0.1 ug (0.0001 mg) of a standard preparation of crystalline estrone.
(05 Mar 2000)
estrous Pertaining to estrus.
Synonym: estrual.
(05 Mar 2000)
estrous cycle The series of physiologic uterine, ovarian, and other changes that occur in higher animals, consisting of proestrus, estrus, postestrus, and anestrus or diestrus.
(05 Mar 2000)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 5 ÆäÀÌÁö: 1
  • Estrogen Antagonists - »õâ Compounds which inhibit or antagonize the action or biosynthesis of estrogenic compounds.
    Synonyms : Antagonists, Estrogen
  • Estrogen Receptor alpha - »õâ One of the ESTROGEN RECEPTORS that has marked affinity for ESTRADIOL. Its expression and function differs from, and in some ways opposes, ESTROGEN RECEPTOR BETA.
    Synonyms : ERalpha, Estradiol Receptor alpha, Estrogen Receptor 1, Estrogen Receptors alpha, Receptor alpha, Estrogen, Receptor alpha, Estradiol, alpha, Estradiol Receptor
  • Estrogen Receptor beta - »õâ One of the ESTROGEN RECEPTORS that has greater affinity for ISOFLAVONES than ESTROGEN RECEPTOR ALPHA does. There is great sequence homology with ER alpha in the DNA-binding domain but not in the ligand binding and hinge domains.
    Synonyms : ERbeta, ERbetacx, Estrogen Receptor 2, Estrogen Receptors beta, Receptor beta, Estrogen
  • Estrogen Receptor Modulators - »õâ Substances that possess antiestrogenic actions but can also produce estrogenic effects as well. They act as complete or partial agonist or as antagonist. They can be either steroidal or nonsteroidal in structure.
    Synonyms : Antiestrogen, Estrogen Receptor Modulator, Modulator, Estrogen Receptor, Modulators, Estrogen Receptor, Receptor Modulator, Estrogen, Receptor Modulators, Estrogen
  • Estrogen Replacement Therapy - »õâ The use of hormonal agents with estrogen-like activity in postmenopausal or other estrogen-deficient women to alleviate effects of hormone deficiency, such as vasomotor symptoms, DYSPAREUNIA, and progressive development of OSTEOPOROSIS. This may also include the use of progestational agents in combination therapy.
    Synonyms : Estrogen Progestin Combination Therapy, Estrogen Progestin Replacement Therapy, Estrogen Replacement, Replacement, Estrogen, Therapy, Estrogen Replacement, Estrogen Replacement Therapies, Estrogen Replacements, Hormone Replacement Therapy, Post Menopausal
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  • Estrogen Replacement Therapy - »õâ
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E08720141 Estradiol hemihydrate
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estrous (of lower mammals) showing or in a state of estrus; in heat; "the estrous state"; "the estrous cycle"
Ãâó: wordnet.princeton.edu/perl/webwn
estrogen a general term for female steroid sex hormones that are secreted by the ovary and responsible for typical female sexual characteristics
Ãâó: wordnet.princeton.edu/perl/webwn
estrogenic relating to or caused by estrogen
Ãâó: wordnet.princeton.edu/perl/webwn
estrone a naturally occurring weak estrogenic hormone secreted by the mammalian ovary; synthesized (trade name Estronol) and used to treat estrogen deficiency
Ãâó: wordnet.princeton.edu/perl/webwn
estrogen replacement therapy supplemental estrogen given to women after surgery or menopause to restore normal levels of estrogen.
Ãâó: www.geocities.com/HotSprings/8741/define.html
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estro a general term for female steroid sex hormones that are secreted by the ovary and responsible for typical female sexual characteristics
estro an antagonist for estrogen that is used in the treatment of breast cancer
estro relating to or caused by estrogen
estro a naturally occurring weak estrogenic hormone secreted by the mammalian ovary
estro a naturally occurring weak estrogenic hormone secreted by the mammalian ovary
estro (of lower mammals) showing or in a state of estrus
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