| epoprostenol | <chemical> A prostaglandin that is biosynthesised enzymatically from prostaglandin endoperoxides in human vascular tissue. It is a potent inhibitor of platelet aggregation. The sodium salt has been also used to treat primary pulmonary hypertension. Pharmacological action: antihypertensive agents, platelet aggregation inhibitors. Chemical name: Prosta-5,13-dien-1-oic acid, 6,9-epoxy-11,15-dihydroxy-, (5Z,9alpha,11alpha,13E,15S)- (12 Dec 1998) |
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Synonyms : Epoprostanol, Epoprostenol Sodium, Epoprostenol Sodium Salt, (5Z, 9alpha, 11alpha, 13E, 15S)-Isomer, Flolan, Prostaglandin I(2)
| epoprostenol |
name given to prostacyclin when used pharmaceutically; it is used in the form of the sodium salt as an inhibitor of platelet aggregation when blood contacts nonbiological systems, as in renal dialysis, as a pulmonary antihypertensive, and as a vasodilator.
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