| IS | ileal segment; immediate sensitivity; immune serum; immunosuppression; impingement syndrome; incenti... |
|---|---|
| RSI | rapid-sequence induction; rapid sequence intubation; repetition strain injury |
| HTLF | human T-cell leukemia virus enhancer factor |
| TEF | thermic effect of food; thyrotroph embryonic factor; tracheoesophageal fistula; transcriptional enha... |
| TFE | polytetrafluoroethylene; transcription factor for immunoglobulin heavy chain enhancer |
| C/EBP | CAAAT/enhancer binding protein |
|---|---|
| C/EBP delta | CCAAT enhancer binding protein delta |
| C/EBP-beta | CCAAAT/enhancer-binding protein-beta |
| C/EBPalpha | CAAT/enhancer binding protein-alpha |
| E(Spl) | Enhancer of split |
| enhancer sequence | <molecular biology> A nucleotide sequence, located as many as several thousand base pairs away in either direction from the target gene, which enhances transcription of that gene. (14 Nov 1997) |
|---|
| HIV enhancer | Cis-acting regulatory sequences in the HIV long terminal repeat (ltr) which play a major role in induction or augmentation of HIV gene expression in response to environmental stimuli such as mitogens, phorbol esters, or other viruses. The HIV enhancer is the binding site for many cellular transcription factors including the nuclear factor nf-kappa b. (12 Dec 1998) |
|---|---|
| enhancer element | <molecular biology> A DNA sequence, present in the genomes of higher eukaryotes and of various animal viruses, which can increase the transcription of genes into messenger RNA. These control element frequently found 5' to the start site of a gene, when bound by a specific transcription factor, enhance the levels of expression of the gene, but are not sufficient alone to cause expression. Distinguished from a promoter, that is alone sufficient to cause expression of the gene when bound, in practice, the two terms merge. Enhancers usually can function in either orientation and at various distances from a promoter. Compare: promoter. (03 Jul 1999) |
| enhancer trap | <molecular biology, technique> Technique for mapping gene expression patterns, classically in Drosophila. A transposon element carrying a reporter gene (usually _ galactosidase), linked to a very weak promoter, is induced to jump within the genome. If the P element re inserts within the sphere of influence of promoters and enhancers of some (random) gene, then reporter gene is also expressed in a similar tissue specific manner. Usually, many lines of flies carrying such random insertions are studied, if a line shows interesting patterns of expression, it can be possible to clone the gene of interest. (18 Nov 1997) |
| alu sequence | Any of a family of short (300 basepairs long) repeated sequences that occur throughout the human genome. (09 Oct 1997) |
| amino acid sequence | The sequence of amino acids as arrayed in chains, sheets, etc., within the protein molecule. This is referred to as the primary structure of proteins. It is of fundamental importance in determining protein conformation. (12 Dec 1998) |
| autonomously replicating sequence | <molecular biology> This is a chromosomal sequence that allows plasmids to replicate on their own in yeast. (02 Jan 1998) |
| base sequence | <molecular biology> The order of nucleotide bases in a DNA molecule. (09 Oct 1997) |
| base sequence analysis | <molecular biology> A method, sometimes automated, for determining the base sequence. (09 Oct 1997) |
| canonical sequence | Of a series of related DNA, RNA or protein sequences, the sequence that reflects the most common choice of base or amino acid at each position. Areas of particularly good agreement often represent conserved functional domains. The generation of consensus sequences has been subjected to intensive mathematical analysis. (18 Nov 1997) |
| carbohydrate sequence | The sequence of carbohydrates within polysaccharides, glycoproteins, and glycolipids. (12 Dec 1998) |
| palindromic sequence | <molecular biology> Nucleic acid sequence that is identical to its complementary strand when each is read in the correct direction (e.g. TGGCCA). Palindromic sequences are often the recognition sites for restriction enzymes. Degenerate palindromes with internal mismatching can lead to loops or hairpins being formed (as in tRNA). (18 Nov 1997) |
| recognition sequence | A nucleotide sequence --typically composed of 4, 6, or 8nucleotides -- that is recognised by a restriction endonuclease. Type II enzymes cut (and theircorresponding modification enzymes methylate) within or very near the recognition sequence. (09 Oct 1997) |
| regulatory sequence | <molecular biology> DNA sequence to which regulatory molecules such as promotors or enhancers bind, thereby altering the expression of the adjacent gene. (18 Nov 1997) |
| centromeric sequence | <molecular biology> Special sequences of DNA nucleotides found on chromosomes which provide a site for the attachment of spindle fibres during nuclear division (mitosis or meiosis). (09 Oct 1997) |
| chi sequence | <molecular biology> A specific sequence of nucleotides on a site on the genome of the bacteria Escherichia coli which strongly encourages recombination and crossing over to occur at that site. (05 Jan 1998) |
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