| END | early neonatal death; endocrinology; endorphin; endothelin |
|---|---|
| ENDR | endothelin receptor |
| ENDRB | endothelin receptor B |
| ET | educational therapy; effective temperature; ejection time; embryo transfer; endothelin; endotoxin; e... |
| ETR | effective thyroxine ratio; endothelin receptor |
| 125I-ET-1 | 125I-endothelin-1 |
|---|---|
| BIG-ET | BIG-endothelin |
| Big ET-1 | Big endothelin-1 |
| ET | Endothelin |
| ET-1 | Endothelin |
| endothelin | <protein> Group of peptide hormones released by endothelial cells. The most potent vasoconstrictor hormones known. Structurally related to the snake venom sarafotoxins. (18 Nov 1997) |
|---|---|
| endothelin receptor | Simple squamous epithelium lining blood vessels, lymphatics and other fluid filled cavities (such as the anterior chamber of the eye). Mesodermally derived, unlike most epithelia. (18 Nov 1997) |
| endothelin-1 | A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (n eng j med 1995;333(6):356-63) (12 Dec 1998) |
| endothelin-2 | A 21-amino acid peptide produced predominantly within the kidney and intestine, with smaller amounts produced in the myocardium, placenta, and uterus, but the cells of origin are not clear. Endothelin-2 has no unique physiologic functions, as compared with endothelin-1. (n eng j med 1995;333(6):356-63) (12 Dec 1998) |
| endothelin-3 | A 21-amino acid peptide that circulates in the plasma, but its source is not known. Endothelin-3 has been found in high concentrations in the brain and may regulate important functions in neurons and astrocytes, such as proliferation and development. It also is found throughout the gastrointestinal tract and in the lung and kidney. (n eng j med 1995;333(6):356-63) (12 Dec 1998) |
| endothelin-valine-generating endopeptidase | <enzyme> Cleaves big endothelin between val22 and asn23 Registry number: EC 3.4.21.- Synonym: big-et-ge (26 Jun 1999) |
| endothelins | 21-amino-acid peptides produced by vascular endothelial cells and functioning as potent vasoconstrictors. The endothelin family consists of three members, endothelin-1, endothelin-2, and endothelin-3. All three peptides contain 21 amino acids, but vary in amino acid composition. The three peptides produce vasoconstrictor and pressor responses in various parts of the body. However, the quantitative profiles of the pharmacological activities are considerably different among the three isopeptides. (12 Dec 1998) |
| receptors, endothelin | Cell surface proteins that bind endothelin with high affinity and trigger intracellular changes which influence the behaviour of cells. (12 Dec 1998) |
|---|
Synonyms : Big Endothelin, Big Endothelin-1, ET-1 (Endothelin-1), Endothelin Type 1, Endothelin, Big, Preproendothelin, Preproendothelin-1, Proendothelin (1-38), Proendothelin-1 Precursor, Big Endothelin 1, Endothelin 1, Endothelin-1, Big, Precursor, Proendothelin-1
Synonyms : Endothelin 2
Synonyms : Big Endothelin 3, Big Endothelin-3, Endothelin 3, Endothelin 3, Big, Endothelin-3, Big
Synonyms : Endothelin, Vasoconstrictor Factors, Endothelium-Derived
| endothelin |
Molecule with potent vasoconstrictor activity. It is expressed by vascular cells, as well as in brain, kidney and lung.
Ãâó: www.nature.com/nrn/journal/v2/n3/glossary/nrn0301_...
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|---|---|
| endothelin-receptor antagonist |
A medicine that lowers blood pressure by opposing the vasoconstricting effects of endothelins.
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