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  • drug-induced autoantibody
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drug-induced cholestasis <hepatology> A condition where a drug is interfering with the normal flow of bile from the liver to the gut via the biliary tract. The end result is jaundice.
Origin: Gr. Stasis = stoppage
(27 Sep 1997)
drug-induced diarrhoea <gastroenterology> Diarrhoea may be produced by several mechanisms. Laxatives may produce diarrhoea by increasing the flow of water into the intestine or by increasing the intestinal motility.
Antibiotic medications can cause diarrhoea by killing the normal bacteria that live in the intestine and help us digest our food. Some drugs produce diarrhoea as a side effect or as drug toxicity.
(27 Sep 1997)
drug-induced disease <pharmacology> A toxic reaction to or morbid condition resulting from the administration of a drug.
(05 Mar 2000)
drug-induced eosinophilic lung disease <radiology> Diffuse reticular pattern: nitrofurantoin, Loeffler-like pattern: penicillin, sulfonamides, ASA, para-ASA, imipramine, HCTZ, cromolyn sodium see: eosinophilic lung disease
(12 Dec 1998)
drug-induced hepatitis <hepatology, pathology> Inflammation and hepatocellular damage of the liver that is caused by a drug.
Some medications may cause inflammation of the liver as a drug side effect or drug toxicity. Drugs that are known to cause hepatitis include acetaminophen, isoniazid, halothane, methyldopa, erythromycin and oral contraceptives.
(27 Sep 1997)
drug-induced lupus <dermatology> An inflammatory autoimmune disorder, similar to lupus, that develops in response to the use of a particular medication. It is characterised by anti-histone antibodies. More benign than the usual disease, with less renal involvement. The syndrome clears after stopping the offending drug.
Drugs that are known to cause this reaction include procainamide, isoniazid, sulphasalazine, hydralazine, methyldopa, phenytoin, chlorpromazine and penicillamine.
The arthritis, cardiac, pulmonary and systemic features may be present, but the kidney involvement (nephritis) and neurologic disease are rare.
Symptoms generally resolve spontaneously after stopping the medication. Complications include myocarditis, pericarditis, thrombocytopenic purpura and infections.
(18 Jul 2002)
drug-induced tremor <neurology, pharmacology> A drug-induced condition where there is shaking (tremor) of the extremities that is increased with purposeful movement.
Drugs known to induce tremor include: theophylline, Alupent, cyclosporine, amphetamines, lithium and caffeine.
(27 Sep 1997)
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  • Drug-induced hepatitis - »õâ
  • Drug-induced hypertension - »õâ
  • Drug-induced hypoglycemia - »õâ
  • Drug-induced hypothyroidism - »õâ
  • Drug-induced immune hemolytic anemia - »õâ
  • Drug-induced immune thrombocytopenia - »õâ
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drug-induced c. allergic cystitis occurring in reaction to a medication; see also chemical c.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
drug-induced immune hemolytic a. immune hemolytic anemia induced by drugs, classified by mechanism as penicillin type, in which the drug, acting as a hapten bound to the red cell membrane, induces the formation of specific antibodies; methyldopa type, in which the drug, possibly by inhibition of suppressor T cells, induces the formation of anti-Rh antibodies; or stibophen or “innocent bystander” type, in which circulating drug-antibody immune complexes bind nonspecifically to red cells. The first two types usually involve warm-reactive antibodies and accelerated sequestration of red cells by the reticuloendothelial system; the third usually involves cold-reactive antibodies and complement-dependent intravascular hemolysis.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
drug-induced l. a syndrome similar to systemic lupus erythematosus, caused by any of various drugs, such as hydralazine, procainamide, isoniazid, D-penicillamine, and chlorpromazine; it usually resolves following withdrawal of the offending drug.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
drug-induced n. that caused by medications; the most common mechanisms are immunological (formation of antibodies destructive to neutrophils or of immune complexes that bind to neutrophils), followed by inhibition of granulopoiesis and direct damage to bone marrow or precursor cells of the granulocytic series.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
drug-induced systemic lupus erythematosus A group of signs and symptoms similar to those of systemic lupus erythematosus, caused by an adverse reaction to drugs, esp. procainamide, hydralazine, and isoniazid. Joint inflammation and pain, skin ra
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