| ¿µ¹® | drug resistance | ÇÑ±Û | ¾à¹°³»¼º |
|---|---|---|---|
| ¼³¸í | 1. ÈÇпä¹ýÁ¦³ª Ç×»ý¹°ÁúÀÇ ¾î¶² ÀÏÁ¤ ³óµµ·Î ¼¼±ÕÀ» Á×À̰ųª Áõ½ÄÀúÇØ¸¦ ¹Þ´Â °ÍÀ» ÀÌ ÈÇпä¹ýÁ¦³ª Ç×»ý¹°Áú¿¡ °¨¼ö¼ºÀÌ ÀÖ´Ù°í Çϴµ¥, ÀÌ °¨¼ö¼ºÀÌ ¾ø°Ô µÈ »ýŸ¦ ÀúÇ×¼ºÀ̶óµç°¡ ³»¼ºÀ̶ó°í ¸»ÇÑ´Ù. µû¶ó¼ º¯À̹̻ý¹°ÀÇ ¾àÁ¦¿¡ ´ëÇÑ ÀÚÇ×¼ºÀ̶óµç°¡ ³»¼ºÀ̶ó°í ¸»ÇÑ´Ù. 2. ÀǾàǰÀ» °è¼Ó º¹¿ëÇϸé Á¡Â÷ Áõ·®ÇÏÁö ¾ÊÀ¸¸é È¿·ÂÀÌ ³ªÅ¸³ªÁö ¾Ê´Â ¼ºÁú. ÀÌ·¯ÇÑ ¶§¸¦ ¾àÁ¦³»¼ºÀÌ »ý°å´Ù°í ÇÑ´Ù. ¸ðµç ¹Ì»ý¹°Àº °¨¼ö¼ºÀ» °¡Áö´Â ¾à¹°¿¡ ÀÇÇÏ¿© »ç¸êµÇÁö¸¸, ¼Ò¼öÀÇ °ÍÀº »ì¾Æ³²¾Æ ±×°ÍÀÌ ÁøÈµÊÀ¸·Î½á »ç¸êÇÏÁö ¾Ê´Â ¼ö°¡ ÀÖ´Ù. ¶Ç, ÃÖÃÊ¿¡´Â °¨¼ö¼ºÀ» °¡Áö°í ÀÖ´ø ±ÕÀÌ Â÷Â÷ ³»¼º±ÕÀ¸·Î µÇ±âµµ ÇÑ´Ù. ¸¹Àº º´¿ø±ÕÀº °¨¼ö¼ºÀÌ ÀÖ´Â ÀǾàǰ¿¡ ´ëÇÏ¿© ³»¼ºÀÌ »ý±ä´Ù. °¡Àå °íµµÀÇ ³»¼º±ÕÀÌ »ý±â±â ½¬¿î °ÍÀº ½ºÆ®·¾Å丶À̽ÅÀε¥ °áÇÙ±Õ°ú ±×¶÷À½¼º±Õ¿¡ ´ëÇÏ¿© ½±°Ô ³»¼ºÀÌ »ý±ä´Ù. Æä´Ï½Ç¸°À̳ª Åׯ®¶ó½ÃŬ¸°(¾ÆÅ©·Î¸¶À̽Å) µîÀÇ Ç×»ý¹°Áúµµ ³»¼ºÀÌ »ý±â±â ½¬¿ì¹Ç·Î, »ç¿ëÇÒ ¶§´Â ÀûÀÀÀ» Àß È®ÀÎÇÏ¿© Çʿ䷮À» Á¤ÇÏ°í ¿¬¿ëÀ» ÇÇÇÑ´Ù. °°Àº È¿°ú°¡ ÀÖ´Â ´Ù¸¥ Á¾·ùÀÇ ¾àÁ¦¸¦ ¼Ò·®¾¿ 2, 3Á¾ º´¿ëÇÏ¸é ³»¼ºÀÇ ¹ß»ýÀÌ Å©°Ô ¾ïÁ¦µÈ´Ù´Â °ÍÀÌ ¾Ë·ÁÁ® ÀÖ´Ù. °áÇÙ¾àÀ¸·Î¼ ½ºÆ®·¾Å丶À̽Űú ÆÄ½º, ¶Ç´Â À̼ҴϾÆÁöµå¸¦ º´¿ëÇÏ´Â °Í µîÀÌ ±× ¿¹ÀÌ´Ù. |
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| ¿µ¹® | neoplasm | ÇÑ±Û | ½Å»ý¹° |
|---|---|---|---|
| ¼³¸í | »õ·Î »ý±ä ¹°ÁúÀ̶ó´Â ¶æÀÌ´Ù. À̰ÍÀº ´Ù¸¥ ¸»·Î ¡°Á¾¾ç(tumor)¡±À̶ó°íµµ ÇÏ´Â µ¥, ½ÇÁ¦·Î À̵éÀÇ ¸íÈ®ÇÑ ¶æÀº ¼·Î ´Ù¸£´Ù. Á¾¾çÀ̶ó´Â ¸»Àº ¡°±× Å©±â°¡ 1cm°¡ ³Ñ´Â ÀÏÁ¾ÀÇ È¤¡±À» ¸»ÇÏ´Â °ÍÀ¸·Î ÇǺΰú¿¡¼´Â À̺¸´Ù ÀÛÀº ȤÀ» ±¸ÁøÀ̶ó°í ÇÏ¿© ±¸º°ÇÏ¿© ºÎ¸¥´Ù. ÇÏÁö¸¸, À̰ÍÀº ¶ÇÇÑ ÇǺλӸ¸ ¾Æ´Ï¶ó ½Åü³» ¾îµð¿¡¼µç »ý±æ ¼ö ÀÖÀ¸¹Ç·Î ¸ðµÎ ÅëĪÇÏ¿© Á¾¾çÀ̶ó°í ºÎ¸¥´Ù. ÀÌ¿¡ ºñÇØ ¡°½Å»ý¹°¡±Àº ½Åü³» ¾ø´ø °ÍÀÌ »õ·Î »ý°Ü³µ´Ù´Â ¶æÀ¸·Î ºÙÀÎ ¸»ÀÌ´Ù. ±×·¯³ª, ÀÌ µÑÀÇ °ü°è¸¦ ¸íÈ®È÷ ±ÔÁ¤ÁþÁö ¾Ê°í ÀÖÀ¸¸ç ´ë°³ °°Àº ¶æÀ¸·Î È¥¿ëµÈ´Ù. ½Å»ý¹°¿¡´Â ¡°¾ç¼º(benign)¡±°ú ¡°¾Ç¼º(malignant)¡±ÀÌ ÀÖ´Ù. ÀÌ µÑÀÇ ±¸º°Àº ¿©·¯ °¡Áö ±âÁØ¿¡ µû¸£Áö¸¸, ¶§·Î´Â ±¸º°ÀÌ ¾î·Á¿ï ¶§µµ ÀÖ´Ù. ´ë°³ ¾ç¼ºÀº »ý¸í´ÜÃàÀ» Àß ÀÏÀ¸Å°Áö ¾Ê´Â °ÍÀ¸·Î Ä¡·áÈÄ¿¡ Àç¹ßµµ Àß ÇÏÁö ¾Ê´Â´Ù. ÀÌ¿¡ ºñÇØ ¾Ç¼ºÀº Àç¹ß»Ó¸¸ ¾Æ´Ï¶ó ´Ù¸¥ ±â°üÀ¸·Î ¿Å°Ü°¡¼ °°Àº º´º¯ÀÌ ¹ß»ýÇÏ´Â ¡°ÀüÀÌ(metastasis)¡±Çö»óµµ ÀϾÙ. µû¶ó¼ »ý¸íÀ» ´ÜÃà½ÃŰ´Â °æ¿ì°¡ ¸¹À¸¸ç, ´ë°³ Ä¡·á°¡ ¾î·Æ´Ù. |
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| ¿µ¹® | resistance | ÇÑ±Û | ³»¼º, ÀúÇ×¼º |
|---|---|---|---|
| ¼³¸í | ¨ç ¾à¹°ÀÇ ¹Ýº¹ º¹¿ë¿¡ ÀÇÇØ ¾àÈ¿°¡ ÀúÇÏÇÏ´Â Çö»ó. ¨è ¼¼±Õ µûÀ§ÀÇ º´¿øÃ¼°¡ ÈÇÐ ¿ä¹ýÁ¦³ª Ç×»ý ¹°ÁúÀÇ °è¼Ó »ç¿ë¿¡ ´ëÇÏ¿© ³ªÅ¸³»´Â ÀúÇ×¼º. ¼¼±ÕÀÇ ³»¼ºÈ¹µæÀÇ ¸ÞÄ¿´ÏÁò¿¡ ´ëÇØ¼´Â ¼¼Æ÷ÀÇ ±¸Á¶(¸®Æ÷Á», ¼¼Æ÷¸·) º¯È, ´ë»ç°èÀÇ º¯È, µ¹¿¬º¯ÀÌ µî¿¡ ÀÇÇÑ ¾à¹°°¨¼ö¼º ÀúÇÏ µîÀÌ ÃßÃøµÇ°í ÀÖ´Ù. ÇÑÆí ´Ù¸¥ ¾à¹°¿¡µµ ³»¼ºÀ» ³ªÅ¸³»´Â ±³Â÷³»¼º°ú, ¿©·¯ Á¾·ùÀÇ ¾à¹°¿¡ µ¿½Ã¿¡ ³»¼ºÀ» ȹµæÇÑ »óŸ¦ ´ÙÁ¦ ³»¼ºÀ̶ó°í ÇÑ´Ù. 3. ȯ°æ Á¶°ÇÀÇ º¯È¿¡ °ßµô ¼ö ÀÖ´Â »ý¹°ÀÇ ¼ºÁú. ³»¿¼º, ³»ÇѼº µûÀ§°¡ ÀÖ´Ù. |
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| ¿µ¹® | resistance | ÇÑ±Û | ÀúÇ× |
|---|---|---|---|
| ¼³¸í | ¨ç¾à¹°ÀÇ ¹Ýº¹ º¹¿ë¿¡ ÀÇÇØ ¾àÈ¿°¡ ÀúÇÏÇÏ´Â Çö»ó. ¨è ¼¼±Õ µûÀ§ÀÇ º´¿øÃ¼°¡ ÈÇÐ ¿ä¹ýÁ¦³ª Ç×»ý ¹°ÁúÀÇ °è¼Ó »ç¿ë¿¡ ´ëÇÏ¿© ³ªÅ¸³»´Â ÀúÇ×¼º. ¼¼±ÕÀÇ ³»¼ºÈ¹µæÀÇ ¸ÞÄ¿´ÏÁò¿¡ ´ëÇØ¼´Â ¼¼Æ÷ÀÇ ±¸Á¶(¸®Æ÷Á», ¼¼Æ÷¸·) º¯È, ´ë»ç°èÀÇ º¯È, µ¹¿¬º¯ÀÌ µî¿¡ ÀÇÇÑ ¾à¹°°¨¼ö¼º ÀúÇÏ µîÀÌ ÃßÃøµÇ°í ÀÖ´Ù. ÇÑÆí ´Ù¸¥ ¾à¹°¿¡µµ ³»¼ºÀ» ³ªÅ¸³»´Â ±³Â÷³»¼º°ú, ¿©·¯ Á¾·ùÀÇ ¾à¹°¿¡ µ¿½Ã¿¡ ³»¼ºÀ» ȹµæÇÑ »óŸ¦ ´ÙÁ¦ ³»¼ºÀ̶ó°í ÇÑ´Ù. ¨é ȯ°æ Á¶°ÇÀÇ º¯È¿¡ °ßµô ¼ö ÀÖ´Â »ý¹°ÀÇ ¼ºÁú. ³»¿¼º, ³»ÇѼº µûÀ§°¡ ÀÖ´Ù. |
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| ¿µ¹® | antihypertensive drug | ÇÑ±Û | °íÇ÷¾Ð¾à, Ç×°íÇ÷¾ÐÁ¦ |
|---|---|---|---|
| ¼³¸í | °íÇ÷¾ÐÀÇ Ä¡·á¿¡ »ç¿ëÇÏ¸ç ³ôÀº Ç÷¾ÐÀ» ³·Ãß´Â ¾à¹°À» ¸»ÇÑ´Ù. °íÇ÷¾Ð¾à¿¡´Â Ç÷°üÆòȰ±Ù¿¡ Á÷Á¢ ÀÛ¿ëÇÏ¿© À̿ϽÃŰ´Â Ç÷°üÈ®ÀåÁ¦(È÷µå¶ó¶óÁø), ±³°¨½Å°æÀÇ È°µ¿À» ¾îµð¼±°¡ Â÷´ÜÇÏ´Â ¾à¹°(·¹¼¼¸£ÇÉ, ¸ÞÆ¿µµÆÄ, ÇÁ·ÎÇÁ¶ó³ë·Ñ), ÀÌ´¢Á¦(ÇÁ·Î¼¼¹Ìµå, ¿¡Å¸Å©¸°»ê)ÀÌ »ç¿ëµÈ´Ù. |
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| IR | drop of voltage across a resistor produced by a current; ileal resection; immune response; immunizat... |
|---|---|
| ER | efficiency ratio; epigastric region; ejection rate; electroresection; emergency room; endoplasmic re... |
| SR | sarcoplasmic reticulum; saturation recovery; scanning radiometer; screen; secretion rate; sedimentat... |
| DA | dark adaptation; dark agouti [rat]; daunomycin; degenerative arthritis; delayed action; Dental Assis... |
| JVP | [POMD P 49 - 52] 1) Jugular Vein Pressure 2) Jugular Venous Pulse ... |
| SMN | Second Malignant Neoplasm |
|---|---|
| MDR | Multi drug resistance |
| MDR | Multiple Drug Resistance |
| MDR-1 | multi-drug resistance gene-1 |
| APC resistance | Resistance to activated protein C |
| drug resistance, neoplasm | Resistance or diminished response of a neoplasm to an antineoplastic agent in humans, animals, or cell or tissue cultures. (12 Dec 1998) |
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| drug resistance | The ability of bacteria and other microorganisms to withstand a drug to which they were once sensitive (and were once stalled or killed outright). (12 Dec 1998) |
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| drug resistance, microbial | The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through plasmids containing resistance factors (r factors). (12 Dec 1998) |
| drug resistance, multiple | Simultaneous resistance to a broad spectrum of structurally and functionally distinct drugs following exposure to a single agent. It is thought to result from the overexpression of genes encoding an integral plasma membrane protein, p-glycoprotein. (12 Dec 1998) |
| drug-drug interaction | The effects that occur when two or more drugs are used together. Such effects include changes of absorption in the digestive tract, changes in rate of the drugs' breakdown in the liver, new or enhanced side effects and changes in the drugs' activity. (09 Oct 1997) |
| antibodies, neoplasm | Immunoglobulins induced by antigens specific for tumours other than the normally occurring histocompatibility antigens. (12 Dec 1998) |
| antigens, neoplasm | Proteins, glycoprotein, or lipoprotein moieties on surfaces of tumour cells that are usually identified by monoclonal antibodies. Many of these are of either embryonic or viral origin. (12 Dec 1998) |
| brain neoplasm | Neoplasms of the part of the central nervous system contained within the cranium. (12 Dec 1998) |
| genes, structural, neoplasm | DNA sequences that code for RNA and for the proteins required for the enzymatic and structural function of neoplastic cells. (12 Dec 1998) |
| mucinous cystic neoplasm of pancreas | <radiology> = macrocystic adenoma of pancreas, cystadenoma / cystadenocarcinoma, M:F = 1:9, 40-60 years of age, malignant or pre-malignant, large mass (mean 12 cm), multilocular cysts, thick septations, tail / body in 85% (unlike adenocarcinoma and microcystic adenoma), hypo-/avascular, Differential diagnosis: panc pseudocyst, ** Cf: microcystic adenoma (12 Dec 1998) |
| histoid neoplasm | Old term for a neoplasm characterised by a cytohistologic pattern that closely resembles the tissue from which the neoplastic cells are derived. (05 Mar 2000) |
| neoplasm | <oncology, pathology> New and abnormal growth of tissue, which may be benign or cancerous. (16 Dec 1997) |
| neoplasm circulating cells | Exfoliate neoplastic cells circulating in the blood and associated with metastasizing tumours. (12 Dec 1998) |
| neoplasm: gallium imaging | <radiology> Useful: Hodgkin disease and histiocytic form of NHL poor sensitivity below the diaphragm, Burkitt lymphoma: almost 100% sensitivity, hepatoma: 90% sensitivity, melanoma: 90% sensitivity, leukaemia possibly useful: NHL: good for large and mediastinal lesions, nodal metastases from seminoma and embryonal cell carcinoma: 87% sensitivity, non-small cell lung CA: 85% sensitive not useful: head and neck, GI (especially adenocarcinoma), breast, gynaecological, kiddie tumours see: gallium: indications (12 Dec 1998) |
| neoplasm invasiveness | Ability of neoplasms to infiltrate and actively destroy surrounding tissue. (12 Dec 1998) |
| neoplasm metastasis | The transfer of a neoplasm from one organ or part of the body to another remote from the primary site. The ability to metastasize is characteristic of all malignant neoplasms. (12 Dec 1998) |
Synonyms : Antineoplastic Agent Resistance, Neoplasm Drug Resistance, Resistance, Antineoplastic Agent, Resistance, Antineoplastic Drug
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