| 영문 | dopamine | 한글 | 도파민 |
|---|---|---|---|
| 설명 | 히드록시티라민으로서 생리활성 아민-카테콜아민의 일종. 분자식은C18H11NO2, 분자량은 153.18이다. 동식물에 존재하는 아미노산의 하나로, 자외선 작용으로 티로신에서 형성되거나 L-Dopa의 탈탄산에 의해 체내에서 생산된다. 멜라닌 색소 합성 과정의 중간 물질로 콩과 식물에 저장되어 있다. 뇌신경 세포의 흥분 전달에 중요한 구실을 한다. 도파민β-산화효소의 작용에 의해 노르아드레날린이 된다. 부신수질-뇌-교감신경계-폐-작은창자-간 등에도 많이 포함되어 있다. 파킨슨 증후군의 경우 뇌 안의 도파민 량이 감소되며, 뇌줄기의 줄무늬체에는 노르아드레날린보다 도파민이 다량 포함되어 있음을 볼 수 있다는 점에서 도파민 자체가 이른바 카테콜아민을 함유하는 작동성 뉴런의 신경전달물질로서 작용하고 있음이 분명해졌다. |
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| 영문 | iodine uptake | 한글 | 요오드 섭취 |
|---|---|---|---|
| 설명 | 소량의 131I를 경구 투여 후 2, 6, 12, 24시간 등 일정한 시간 경과 후 갑상샘에서의 섭취율을 측정하는 것으로 전반적 갑상샘 기능 상태를 측정하는 검사법이다. |
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| MAOI | MonoAmine Oxidase Inhibitors |
|---|---|
| DBH | Dopamine-Beta(β)-Hydroxylase |
| DA | dark adaptation; dark agouti [rat]; daunomycin; degenerative arthritis; delayed action; Dental Assis... |
| DBH | dopamine beta-hydroxylase |
| DM | defined medium; dermatomyositis; Descemet's membrane; dextromaltose; dextromethorphan; diabetes mell... |
| SSRI | Specific serotonin re-uptake inhibitors |
|---|---|
| Uptake-1 | uptake |
| AChE-I | acetylcholine esterase inhibitors |
| ChEI | Cholinesterase inhibitors |
| IAPs | Inhibitors of apoptosis |
striate body neurosis
| dopamine uptake inhibitors | Drugs that block the transport of dopamine into axon terminals or into storage vesicles within terminals. most of the adrenergic uptake inhibitors also inhibit dopamine uptake. (12 Dec 1998) |
|---|
| adrenergic uptake inhibitors | Drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants (antidepressive agents, tricyclic) and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin. (12 Dec 1998) |
|---|---|
| serotonin uptake inhibitors | Compounds that specifically inhibit the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. These agents have been used in treatment of depression, panic disorder, obsessive-compulsive behaviour, and alcoholism, as analgesics, and to treat obesity and bulimia. Many of the adrenergic uptake inhibitors also inhibit serotonin uptake; they are not included here. (12 Dec 1998) |
| neurotransmitter uptake inhibitors | Drugs that inhibit the transport of neurotransmitters into axon terminals or into storage vesicles within terminals. For many transmitters, uptake determines the time course of transmitter action so inhibiting uptake prolongs the activity of the transmitter. Blocking uptake may also deplete available transmitter stores. Many clinically important drugs are uptake inhibitors although the indirect reactions of the brain rather than the acute block of uptake itself is often responsible for the therapeutic effects. (12 Dec 1998) |
| receptors, dopamine | Cell-surface proteins that bind dopamine with high affinity and trigger intracellular changes influencing the behaviour of cells. (12 Dec 1998) |
| receptors, dopamine d1 | A class of dopamine receptors identified by their binding profiles for synthetic ligands, their molecular biology, and, perhaps, by their mode of action. (12 Dec 1998) |
| receptors, dopamine d2 | A class of dopamine receptors identified by their binding profiles for synthetic ligands, their molecular biology, and, perhaps, their mode of action. (12 Dec 1998) |
| dopamine | <drug> A catecholamine neurotransmitter and hormone (153 D), formed by decarboxylation of dehydroxyphenylalanine (dopa). A precursor of adrenaline and noradrenaline. Pharmacologic action: 1. Precursor of norepinephrine 2. Stimulates dopaminergic, alpha and beta-1 adrenergic receptors: 3. Dopaminergic (1-2 mcg/kg per min): cerebral, renal, and mesenteric vasodilation increase urine output 4. Mixed alpha and beta-1 (2-10 mcg/kg per min): increases cardiac ouput with moderate increase systemic vascular resistance 5. Predominantly alpha (>20 mcg/kg per min): increases systemic vascular resistance Uses: 1. Treat hypotension associated with bradycardia 2. Stimulate cardiac output and urine output Dose: 1. Start infusion at 1-5 mcg/kg per min and titrate to effect. 2. Use the lowest dose that provides the desired hemodynamic improvement. 3. Do not exceed 20 mcg/kg per min. Potential complications: 1. May increase pulmonary pressure and worsen pulmonary congestion. 2. May increase myocardial work without improving coronary blood flow, exacerbating myocardial ischemia 3. Stimulates heart rate and may cause supraventricular or ventricular arrhythmias (15 Mar 2000) |
| dopamine agents | Any drugs that are used for their effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons. (12 Dec 1998) |
| dopamine agonists | Drugs that bind to and activate dopamine receptors. (12 Dec 1998) |
| dopamine antagonists | Drugs that bind to but do not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists. Many drugs used in the treatment of psychotic disorders (antipsychotic agents) are dopamine antagonists, although their therapeutic effects may be due to long-term adjustments of the brain rather than to the acute effects of blocking dopamine receptors. Dopamine antagonists have been used for several other clinical purposes including as antiemetics, in the treatment of tourette syndrome, and for hiccup. (12 Dec 1998) |
| dopamine beta-hydroxylase | <enzyme> Chemical name: 3,4-Dihydroxyphenethylamine, ascorbate:oxygen oxidoreductase (beta-hydroxylating) Registry number: EC 1.14.17.1 (12 Dec 1998) |
| dopamine beta-monooxygenase | A copper-containing enzyme catalyzing oxidation of ascorbate and 3,4-dihydroxyphenylethylamine simultaneously by O2 to yield norepinephrine, dehydroascorbate, and water; a crucial step in catecholamine metabolism. Synonym: dopamine beta-hydroxylase. (05 Mar 2000) |
| dopamine hydrochloride | A biogenic amine and neural transmitter substance, used as a vasopressor agent for treatment of shock. (05 Mar 2000) |
| Amine Precursor Uptake and Decarboxylation | <pharmacology, physiology> Paracrine cells of which argentaffin cells are an example. Usage of the term APUD is neither helpful nor memorable. Acronym: APUD (11 Nov 1997) |
| gallium uptake with normal chest film | <radiology> Pulmonary drug toxicity, tumour infiltration, sarcoidosis, pneumocystis carinii see: lung: gallium imaging (12 Dec 1998) |
Synonyms : Inhibitors, Dopamine Reuptake, Inhibitors, Dopamine Uptake, Reuptake Inhibitors, Dopamine, Uptake Inhibitors, Dopamine
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|