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| DC | daily census; data communication; data conversion; decrease; deep compartment; Dental Corps; deoxych... |
|---|---|
| DCT | direct Coombs' test; discrete cosine transform; distal convoluted tubule; diurnal cortisol test; dyn... |
| DAT | delayed-action tablet; dementia Alzheimer's type; dental aptitude test; diacetylthiamine; diet as to... |
| AGT | Anti-Globulin Test = Coombs' Test |
| CT | calcitonin; calf testis; cardiac tamponade; cardiothoracic [ratio]; carotid tracing; carpal tunnel; ... |
| DAT | DIRECT AGGLUTINATION TEST |
|---|---|
| DAT | Direct Antiglobulin Test |
| MTD | Mycobacterium Tuberculosis Direct Test |
| D | Direct |
| DC | Direct Current |
| direct Coombs' test | A test for detecting sensitised erythrocytes in erythroblastosis foetalis and in cases of acquired immune haemolytic anaemia: the patient's erythrocytes are washed with saline to remove serum and unattached antibody protein, then incubated with Coombs' anti-human globulin (usually serum from a rabbit or goat previously immunised with human globulin); after incubation, the system is centrifuged and examined for agglutination, which indicates the presence of so-called incomplete or univalent antibodies on the surface of the erythrocytes. (05 Mar 2000) |
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| coombs' test | Haemagglutination test in which coombs' reagent (antiglobulin, or anti-human globulin rabbit immune serum) is added to detect incomplete (non-agglutinating, univalent, blocking) antibodies coating erythrocytes. The direct test is applied to red cells which have been coated with antibody in vivo (e.g., in haemolytic disease of newborn, autoimmune haemolytic anaemia, and transfusion reactions). The indirect test is applied to serum to detect the presence of antibody (e.g., in detection of incompatibility in cross-matching tests, detection and identification of irregular antibodies, and in detection of antibodies not identifiable by other means). (12 Dec 1998) |
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| indirect Coombs' test | A test routinely performed in cross-matching blood or in the investigation of transfusion reaction: test for patient's serum is incubated with a suspension of donor erythrocytes; if specific antibodies are present, they become attached to the antigen in donor's cells; after a washing with saline, Coombs' antihuman globulin is added; agglutination at this point indicates that antibodies present in the original test serum had indeed become attached to donor erythrocytes. (05 Mar 2000) |
| direct fluorescent antibody test | Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (fluorescent antibody technique, direct) or an indirect method, by formation of antigen-antibody complex which is then labelled with fluorescein-conjugated anti-immunoglobulin antibody (fluorescent antibody technique, indirect). The tissue is then examined by fluorescence microscopy. (12 Dec 1998) |
| Carey Coombs murmur | A blubbering apical middiastolic murmur occurring in the acute stage of rheumatic mitral valvulitis and disappearing as the valvulitis subsides. Synonym: Coombs murmur. (05 Mar 2000) |
| Gell and Coombs Classification | A classification system that differentiates the 4 types of hypersensitivity reactions: Type I: anaphylactic reactions, Type II: cytotoxic reactions, Type III: immune complex reactions, and Type IV: cell-mediated reactions. (05 Mar 2000) |
| Coombs, Carey | <person> English physician, 1879-1932. See: Coombs murmur. (05 Mar 2000) |
| Coombs murmur | A blubbering apical middiastolic murmur occurring in the acute stage of rheumatic mitral valvulitis and disappearing as the valvulitis subsides. Synonym: Coombs murmur. (05 Mar 2000) |
| coombs' reaction | An immunological lab test to detect antibodies which attack the red blood cells of its own body (called autoantibodies). The test is important to the diagnosis of certain blood disorders. The test first reacts red blood cells with serum from the test individual, then with antibodies to the autoantibodies. If the autoantibodies exist, they will bind to the red blood cells. When the antibodies to the autoantibodies are added, they will bind the autoantibodies (still attached to the red blood cells) and cause the red blood cells to clump together. Large clumps of red blood cells indicate that the autoantibodies exist, absence of the clumps indicates that they don't. (09 Oct 1997) |
| Coombs, Robin | <person> English veterinarian and immunologist, *1921. See: Gell and Coombs reactions, Coombs' serum, Coombs' test, direct Coombs' test, indirect Coombs' test. (05 Mar 2000) |
| Coombs' serum | Serum from a rabbit or other animal previously immunised with purified human globulin to prepare antibodies directed against IgG and complement; used in the direct and indirect Coombs' tests. Synonym: Coombs' serum. (05 Mar 2000) |
| non-direct transmission | <epidemiology> A mode of transmission that differs in some mysterious way from indirect transmission. (05 Dec 1998) |
| direct | 1. Straight, in a straight line. 2. Performed immediately and without the intervention of subsidiary means. Origin: L. Directus (18 Nov 1997) |
| direct acrylic restoration | A direct resin restoration of autopolymerizing acrylic. (05 Mar 2000) |
| direct agglutination | A general term for techniques which use the agglutination (macroscopic clumping) of particulate reagents as an indicator of the presence of an antigen-antibody reaction. Examples (haemagglutination, latex agglutination and coagglutination) follow. (05 Mar 2000) |
| direct B-cell | Lymphocytes responding to a small range of antigens by antibody production without any requirement for T-cells. The antigens include flagellin and pokeweed mitogen. (18 Nov 1997) |
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