| ¿µ¹® | toxin | ÇÑ±Û | µ¶¼Ò |
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| ¿µ¹® | diphtheria | ÇÑ±Û | µðÇÁÅ׸®¾Æ |
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| ¼³¸í | µðÇÁÅ׸®¾Æ±ÕÀÌ ±âµµÀÇ »óºÎ¿¡ ´Þ¶óºÙ¾î µ¶¼Ò¸¦ ¹ß»êÇÏ¿© ±× ºÎÀ§ÀÇ ¼¼Æ÷¸¦ ÆÄ±«ÇÏ°í ±× ¼Ó¿¡¼ Áõ½ÄÇÏ¸é¼ µ¶¼Ò¸¦ ¼øÈ¯Ç÷¾× ¼ÓÀ¸·Î º¸³»¾î ½ÉÀå, ¸»ÃÊ½Å°æ µîÀÇ ¿ø°ÝÀå±â ¹× Á¶Á÷ÀÇ ±â´ÉÀ» ÀúÇØÇÏ´Â º´À» À̸£´Â ¸». ÀÌ º´À» ÀÏÀ¸Å°´Â º´¿øÃ¼ÀÇ Á¤½Ä ¸íĪÀº Corynebacterium diphtheriaeÀε¥, ±× º´¿ø±ÕÀÌ »ý»êÇÏ´Â µ¶¼Ò°¡ ¾ÆÁÖ Ä¡¸íÀûÀÎ È¿°ú¸¦ ³ªÅ¸³½´Ù. »ç¶÷ÀÇ °¨¿°¿¡¼µµ ±× µ¶¼ÒÀÇ µ¶¼ºÀÌ °¡Àå ¹®Á¦°¡ µÇ´Âµ¥ ÀÌ µ¶¼ÒÀÇ µ¶¼ºÀº ¸Å¿ì °ÇÏ¿© µ¶¼Ò 0.0001mgÀ¸·Î Á¦¹ý Å« Á㸦 Á×ÀÏ ¼ö ÀÖ´Ù. »ó±âµµ·Î ħÀÔÇÏ¿© ±×°÷¿¡ ÇϾá»öÀÇ °ÅÁþ¸·(pseudomembrane)À» Çü¼ºÇÔÀ¸·Î½á È£Èí°ï¶õÀ» ÀÏÀ¸Å²´Ù. À§¸·Àº â¹éÇÑ ºû±òÀ» ¶í µÎÅÍ¿î Á¶Á÷Àε¥ Á×Àº µðÇÁÅ׸®¾Æ±Õ, µ¶¼Ò ¶§¹®¿¡ Á×Àº ¼¼Æ÷¿Í ±×°Í¿¡ ´ëÇÑ ¹ÝÀÀÀ¸·Î Á¦ÀÛµÈ ¼¶À¯¼º ¹°Áú µîÀ¸·Î ÀÌ·ç¾îÁ® ÀÖ´Ù. ÀÌ Á¶Á÷Àº ÇϺÎÁ¶Á÷°ú ´Ü´ÜÈ÷ °áºÎµÇ¾î ÀÖ¾î¼ ¾ïÁö·Î ¹Ú¸®Çϸé ÃâÇ÷ÇÑ´Ù. ÀÌ À§¸·ÀÌ ÀÎÈĵο¡¼ ±â°üÁö¿¡±îÁö ÆÄ±ÞµÇ¾î È£Èí°ï¶õÀ» ÀÏÀ¸Å²´Ù. ¼º±â, ´«, ±Í µîÀÌ Á¦1Â÷ º´¼Ò·Î µÇ´Â ¼öµµ ÀÖ´Ù. µðÇÁÅ׸®¾Æ µ¶¼Ò´Â ¼¼Æ÷ ¼ÓÀ¸·Î ħÀÔÇÏ¿© ¼¼Æ÷ÀÇ ±â´ÉÀ» Á¤Áö½Ã۴µ¥, ƯÈ÷ ½ÉÀå±Ù¼¼Æ÷¿Í ¸»ÃʽŰ濡¼ Àå¾Ö¸¦ ÀÏÀ¸Å°´Â ¿¹°¡ ¸¹´Ù. Àẹ±â´Â 1~7ÀÏÀ̸ç ÃʱâÁõ»óÀº ¾î´À ºÎÀ§¿¡ À§¸·ÀÌ Çü¼ºµÇ¾ú´ÂÁö ¿©ºÎ¿Í ±× À§¸· Çü¼ºÀÌ ¾î´À Á¤µµÀÇ ¹üÀ§¿¡ ¹ÌÄ¡´Â°¡¿¡ µû¶ó¼ °áÁ¤µÈ´Ù. µðÇÁÅ׸®¾Æ°¡ »ý»êÇÏ´Â µ¶¼Ò°¡ µðÇÁÅ׸®¾Æ°¡ ÀÏÀ¸Å°´Â ¹®Á¦ Áß¿¡¼ °¡Àå Å« ¿øÀÎÀ» Â÷ÁöÇϰí ÀÖÀ¸¹Ç·Î ±× µ¶¼ÒÀÇ »ý¹°ÇÐÀû ±â´ÉÀ» ¾ø¾Ö´Â Ç×ü¸¦ ¸¸µé¾î¼ Åõ¿©ÇÏ´Â Ç×Ç÷û¿ä¹ýÀÌ ½ÃÇàµÇ¾î¼ Ä¡¸íÀ²Àº 3~20%·Î ³·¾ÆÁ³À¸³ª Èĵθ¦ ħ¹ü´çÇÑ Áõ·ÊÀÇ °æ¿ì¿¡´Â ¾ÆÁ÷µµ Ä¡»çÀ²ÀÌ ³ô´Ù. µðÇÁÅ׸®¾Æ¿¡ ´ëÇÑ ¿¹¹æÁ¢Á¾À¸·Î À¯º´ÀÚ°¡ ÁÙ¾úÀ¸¸ç Ä¡»çÀ²µµ 10ºÐÀÇ 1·Î ÁÙ¾ú´Ù. |
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| ¿µ¹® | diagnostic radiology | ÇÑ±Û | Áø´Ü¹æ»ç¼±°úÇÐ |
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| ¼³¸í | °¢Á¾ ¿µ»óÁø´Ü¹ýÀ» ÀÌ¿ëÇÑ Áúº´ÀÇ Áø´Ü ¹× Ä¡·á¸¦ ÀÌ¿ëÇÑ Áúº´ÀÇ Áø´Ü ¹× Ä¡·á¸¦ ´ã´çÇÏ´Â Çй®ÀÌ´Ù. Çö´ëÀÇÇп¡¼ Áúº´ÀÇ Áø´ÜÀº Å©°Ô 3°¡Áö ¹æ¹ýÀ¸·Î ±¸ºÐÇÑ´Ù. Áï ¹®Áø-½ÃÁø-ÃËÁø-ŸÁø-ûÁø µîÀÇ ÀüÅëÀû ¹æ¹ý°ú ±Ù·¡¿¡ ¹ßÀüµÈ °Ë»ç½Ç Áø´Ü, ¿µ»óÁø´ÜÀÌ ÀÖ´Ù. ÀÌÁß¿¡¼ ¿µ»óÁø´ÜÀº ÀÎü ³»ºÎÀå±â¿Í Áúº´ÀÇ »óŸ¦ ´«À¸·Î Á÷Á¢ º¼ ¼ö ÀÖÀ¸¹Ç·Î, Áúº´ÀÇ Áø´Ü¿¡ ÀÖ¾î¼ °¡Àå Áß¿äÇÑ Áø´Ü¹æ¹ýÀ¸·Î ³Î¸® »ç¿ëµÇ°í ÀÖ´Ù. ¶ÇÇÑ Áø´Ü¹æ»ç¼±°úÇÐÀº ÀÌ¿Í °°Àº Áúº´ÀÇ Áø´Ü»Ó¸¸ ¾Æ´Ï¶ó ¼ö¼ú ¶Ç´Â ³»°úÀû Ä¡·á¸¦ ´ë½ÅÇÒ ¼ö ÀÖ´Â Ä¡·á¹æ¹ýÀ» °³¹ßÇÏ¿© ÇöÀç Ä¡·áÀÇ ÇÑ ºÐ¾ßµµ ´ã´çÇϰí ÀÖ´Ù. Áø´Ü¹æ»ç¼±°úÇÐÀº Ãë±ÞÇÏ´Â ¿µ»óÁø´Ü¹æ¹ýÀÌ ´ÙÁßÀçÀû ¹æ»ç¼± ºÐ¾ß, ÇÙÀÇÇÐ ºÐ¾ß, ¿µ»óÁø´Ü ºÐ¾ß µîÀ¸·Î ºÐ·ùµÈ´Ù. ¶ÇÇÑ ¿µ»óÁø´ÜºÐ¾ßµµ ÀÎüÀÇ Áß¿äÇÑ Àå±âº°·Î ÀÏ¹Ý ¹æ»ç¼±Áø´Ü-½Å°æ°è-½ÉÇ÷°ü°è-¼Òȱ⠹æ»ç¼±Áø´Ü µîÀ¸·Î ¼¼ºÐȵǰí ÀÖ´Ù. ÇöÀç ½Ç¿ëÈµÈ ÃÊÀ½ÆÄ Áø´Ü-Àü»êÈ ´ÜÃþ ÃÔ¿µ¼ú-Àڱ⠰ø¸í ¿µ»ó¼ú µîÀº ÄÄÇ»ÅÍ¿Í ÀüÀÚ°øÇÐÀÇ ¹ßÀüÀÌ ÀÇÇп¡ Àû¿ëµÈ ¿µ»óÁø´ÜºÐ¾ßÀÌ´Ù. Áø´Ü¹æ»ç¼±°úÇÐÀº ÁúȯÀÇ ÇàÅÂÇÐÀûÀÎ Áø´ÜÀÌ º¸´Ù Á¤¹ÐȵÊÀ¸·Î½á »ýüÁ¶Á÷¿¡ ´ëÇÑ ÀüÀÚÇö¹Ì°æÀû °Ë»ç¿Íµµ ¿¬°üµÉ ¼ö ÀÖ°Ô µÉ °ÍÀÌ´Ù. ¶ÇÇÑ ¿µ»óÁø´ÜÀÇ ¼öÁØÀ» ÇüÅÂÇÐÀû °Ë»ç¿¡¼ ÇѰÉÀ½ ³ª¾Æ°¡ »ý¸®Àû-»ýÈÇÐÀû Çö»óÀÇ ¿µ»óȸ¦ ½ÇÇöÇϰí À̸¦ ÇüÅÂÇÐÀû Áø´Ü°ú Á¢¸ñ½ÃÅ´À¸·Î½á ÀÎü³»ºÎÀÇ ¸ðµç »óŸ¦ õ¸®¾ÈÀ¸·Î Åõ½ÃÇÏ´Â ¼öÁØ¿¡ °ð µµ´ÞÇÏ°Ô µÉ °ÍÀ¸·Î ¿¹»óµÇ°í ÀÖ´Ù. |
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| TAT | 1) Thematic Apperception Test; ÁÖÁ¦ Åë°¢ °Ë»ç 2) (Equine) Tetanus Anti-Toxin; Ç×... |
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| DC | daily census; data communication; data conversion; decrease; deep compartment; Dental Corps; deoxych... |
| CDT | carbohydrate-deficient transferrin; carbon dioxide therapy; Certified Dental Technician; children's ... |
| DTA | differential thermal analysis; diphtheria toxin A |
| DTN | diphtheria toxin, normal |
| DT | Diphtheria Toxin |
|---|---|
| DTX | Diphtheria toxin |
| DtxR | Diphtheria toxin repressor |
| DT-A | diphtheria toxin |
| DT-A | diphtheria toxin A |
| diagnostic diphtheria toxin | Corynebacterium diphtheriae toxin diluted so that the inoculated dose (0.1 or 0.2 ml) will contain 1/50 th of guinea pig minimal lethal dose. See: Schick test. Synonym: diagnostic diphtheria toxin. (05 Mar 2000) |
|---|---|
| diphtheria toxin | <protein> An ab exotoxin (62 kD) coded by _ corynephage of virulent Corynebacterium diphtheriae strains (that can produce a repressor of toxin production). The B subunit binds to receptors on the surface of the target cell and facilitates the entry of the enzymically active A subunit (21 kD) that ADP ribosylates elongation factor 2, thereby halting mRNA translation. (18 Nov 1997) |
| vaccines, inactivated | Vaccines in which the infectious microbial nucleic acid components have been destroyed by chemical or physical treatment (e.g., formalin, beta-propiolactone, gamma radiation) without affecting the antigenicity or immunogenicity of the viral coat or bacterial outer membrane proteins. (12 Dec 1998) |
| inactivated polio vaccine | <pharmacology, virology> An inactivated vaccination, administered by injection to children for protection against the polio virus. Typically given at 2, 4 and 15 months. A final vaccine is recommended at 4-6 years. (27 Sep 1997) |
| inactivated poliovirus vaccine | Inactivated poliovirus vaccine (IPV), an aqueous suspension of inactivated strains of poliomyelitis virus (types 1, 2, and 3) used by injection; has largely been replaced by the oral vaccine. See: Salk vaccine. (05 Mar 2000) |
| inactivated serum | <immunology> Serum that has been heated 50°C for 30 minutes to destroy the lytic activity of complement. (05 Mar 2000) |
| avian diphtheria | An infection by the fowlpox virus in which tracheal involvement is especially severe. See: fowlpox. Synonym: fowl diphtheria. (05 Mar 2000) |
| calf diphtheria | A necrotic oropharyngolaryngitis of calves associated with Fusobacterium necrophorum infection that may spread to the lungs. (05 Mar 2000) |
| cutaneous diphtheria | An ulcer resulting from infection of the skin by Corynebacterium diphtheriae; systemic manifestations are the same as those of pharyngeal diphtheria. (05 Mar 2000) |
| diphtheria | <infectious disease> An acute infectious disease caused by toxigenic strains of Corynebacterium diphtheriae, acquired by contact with an infected person or a carrier of the disease, which is usually confined to the upper respiratory tract. It is characterised by the formation of a tough membrane (false membrane or pseudomembrane) attached firmly to the underlying tissue that will bleed if forcibly removed. In the most serious infections the membrane begins in the tonsillar (faucial) area on one tonsil and may spread to involve the other tonsil, uvula, soft palate and pharyngeal wall, from where it may extend to the larynx, trachea and bronchial tree and may cause bronchial obstruction and death by hypoxia. Diphtheria also occurs in a cutaneous form and may rarely involve the eyes, middle ear, buccal mucosa, genitalia and umbilical stump, usually secondarily. Systemic effects, chiefly myocarditis and peripheral neuritis, are caused by the exotoxin produced by C. Diphtheriae. Synonym: Bretonneau's angina. Origin: Gr. Diphthera = leather (18 Nov 1997) |
| diphtheria antitoxin | An equine antitoxin against the toxin of corynebacterium diphtheriae, used for the treatment of diphtheria. It is to be differentiated from diphtheria toxoid which is used for the prevention of diphtheria. (12 Dec 1998) |
| diphtheria antitoxin unit | The antitoxin activity of 0.0628 mg standard diphtheria antitoxin. (05 Mar 2000) |
| diphtheria-tetanus-pertussis vaccine | A vaccine consisting of diphtheria toxoid, tetanus toxoid, and pertussis vaccine. It is usually given to infants three times at two-month intervals, generally at 2, 4, and 6 months of age. The vaccine protects against diphtheria, tetanus, and whooping cough. In most cases the vaccine causes only a temporary fever and discomfort, but in a few cases serious neurological side effects have been observed. (12 Dec 1998) |
| diphtheria toxoid | The formaldehyde-inactivated toxin of corynebacterium diphtheriae. It is generally used in mixtures with tetanus toxoid and pertussis vaccine (dtp) or with tetanus toxoid alone (dt for paediatric use and td, which contains 5- to 10-fold less diphtheria toxoid, for other use). Diphtheria toxoid is used for the prevention of diphtheria; diphtheria antitoxin is for treatment. (12 Dec 1998) |
| false diphtheria | 1. One of a group of local infections suggesting diphtheria, but caused by microorganisms other than Corynebacterium diphtheriae. Synonym: Epstein's disease, false diphtheria, pseudodiphtheria. 2. Any microorganism resembling Corynebacterium diphtheriae. Origin: diphtheria + G. Eidos, resemblance (05 Mar 2000) |
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