| DDNTP | dideoxynucleoside triphosphate |
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| ddNTP | dideoxynucleoside triphoshate |
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| dideoxynucleosides | <chemical> Nucleosides that have two hydroxy groups removed from the sugar moiety. The majority of these compounds have broad-spectrum antiretroviral activity due to their action as antimetabolites. The nucleosides are phosphorylated intracellularly to their 5'-triphosphates and act as chain-terminating inhibitors of viral reverse transcription. Pharmacological action: antimetabolites, antiviral agents, reverse transcriptase inhibitors. (12 Dec 1998) |
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Synonyms : ddNus, 2', 3' Dideoxynucleosides
| dideoxynucleoside |
any of a group of synthetic nucleoside analogues lacking two deoxy groups; several 2′,3′-dideoxynucleosides inhibit the enzyme reverse transcriptase and thus have antiretroviral activity.
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