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| HSA | Hazardous Substances Act; Health Services Administration; health systems agency; hereditary siderobl... |
|---|---|
| EDRF | Endothelium Derived Relaxing Factor |
| ENKAF | Epidermal-derived NK cell-Activating Factor |
| ETAF | Epidermal cell derived Thymocyte Activating Factor |
| PDGF-B | Platelet-Derived Growth Factor-B |
| 125I-BSA | 125 bovine serum albumin |
|---|---|
| BSA | 125)I-bovine serum albumin |
| HSA | 99m)Tc-human serum albumin |
| MAA | 99m)Tc-macroaggregated albumin |
| 99mTC-MAA | 99mTC-macroaggregate albumin |
| brain-derived growth factor | <growth factor> Small basic protein purified from pig brain, a member of the family of neurotrophic factors that also includes Nerve Growth Factor and neurotrophin 3. In contrast to nerve growth factor, brain-derived neurotrophic factor is predominanantly (though not exclusively) localised in the CNS. It supports the survival of primary sensory neurons originating from the neural crest and ectodermal placodes that are not responsive to NGF. In the brain brain-derived neurotrophic factor has a trophic action on retinal, cholinergic, and dopaminergic neurons, and in the peripheral nervous system it acts on both motor and sensory neurons. Acronym: BDGF (12 Dec 1998) |
|---|---|
| brain-derived neurotrophic factor | <growth factor> Small basic protein purified from pig brain, a member of the family of neurotrophic factors that also includes Nerve Growth Factor and neurotrophin 3. In contrast to nerve growth factor, brain-derived neurotrophic factor is predominanantly (though not exclusively) localised in the CNS. It supports the survival of primary sensory neurons originating from the neural crest and ectodermal placodes that are not responsive to NGF. In the brain brain-derived neurotrophic factor has a trophic action on retinal, cholinergic, and dopaminergic neurons, and in the peripheral nervous system it acts on both motor and sensory neurons. Acronym: BDGF (12 Dec 1998) |
| mammary derived growth inhibitor | Fatty acid binding protein that inhibits proliferation of mammary carcinoma cells. (18 Nov 1997) |
| receptors, platelet-derived growth factor | Specific molecular sites or structures on cell membranes that react with platelet-derived growth factor, its analogs, or antagonists, to elicit or to inhibit the specific response of the cell to this factor. Pdgf binds with different affinities and specificities to two structurally related receptors, the alpha-receptor and the beta-receptor. Both of these receptors are transmembrane proteins with an intracellular, ligand-stimulatable protein kinase domain. (12 Dec 1998) |
| refuse-derived fuel | (RDF) Fuel prepared from municipal solid waste. Noncombustible materials such as rocks, glass, and metals are removed, and the remaining combustible portion of the solid waste is choped or shreaded. RDF facilities process between 100 and 3000 tons of MSW per day. (05 Dec 1998) |
| monocyte derived neutrophil chemotactic factor | <cytokine> A cytokine that activates neutrophils and attracts neutrophils and T-lymphocytes. It is released by several cell types including monocytes, macrophages, T-lymphocytes, fibroblasts, endothelial cells, and keratinocytes by an inflammatory stimulus. Il-8 is a member of the beta-thromboglobulin superfamily and structurally related to platelet factor 4. Acronym: IL-8 (12 Dec 1998) |
| platelet-derived growth factor | <growth factor> The major mitogen in serum for growth in culture of cells of connective tissue origin. It consists of 2 different but homologous polypeptides A and B (~30,000 D) linked by disulphide bonds. Believed to play a role in wound healing. It is carried in the alpha-granules of platelets and is released when platelets adhere to traumatised tissues. Connective tissue cells near the traumatised region respond by initiating the process of replication. The B chain is almost identical in sequence to p28sis, the transforming protein of simian sarcoma virus, that can transform only those cells that express receptors for platelet derived growth factor, suggesting that transformation is caused by autocrine stimulation. The receptor is a tyrosine kinase. Acronym: PDGF (12 Dec 1998) |
| schwannoma derived growth factor | <growth factor> A growth factor containing an EGF like domain, mitogenic for astrocytes, Schwann cells and fibroblasts. (18 Nov 1997) |
| derived protein | A derivative of protein effected by chemical change, e.g., hydrolysis. (05 Mar 2000) |
| oxygen derived free radicals | An atom or atom group having an unpaired electron on an oxygen atom, typically derived from molecular oxygen. For example, one-electron reduction of O2 produces the superoxide radical, O2-; other examples include the hydroperoxyl radical (HOO-), the hydroxyl radical (HO-), and nitric oxide (NO-). (05 Mar 2000) |
| thymus derived lymphocyte | <haematology, immunology> A class of lymphocytes, so called because they are derived from the thymus and have been through thymic processing. Involved primarily in controlling cell-mediated immune reactions and in the control of B-cell development. The T-cells coordinate the immune system by secreting lymphokine hormones. There are 3 fundamentally different types of t cells : helper, killer, and suppressor. Each has many subdivisions. T-cells are also called t lymphocytes. They bear T-cell antigen receptors (CD3) and lack Fc or C3b receptors. Major T-cell subsets are CD4 (mainly helper cells) and CD8 (mostly cytotoxic or suppressor T-cells). Uncontrolled proliferation of this type of cell gives rise to T-cell leukaemia/lymphoma. (21 Jun 1999) |
| endothelium-derived growth factor synthase | <enzyme> Converts l-arginine to a smooth muscle relaxing factor and stimulates the formation of cyclic-GMP Registry number: EC 1.5.1.- Synonym: edrf synthase (26 Jun 1999) |
| endothelium derived relaxation factor | <biochemistry> This compound is produced from L arginine by the enzyme nitric oxide synthase. Acts as a potent vasorelaxant via elevation of intracellular cGMP in vascular smooth muscle. Synthesis of nitric oxide is not confined to endothelium, isoforms of nitric oxide synthase are also found in brain, neutrophils and platelets. Synonym: endothelium derived relaxation factor. Acronym: NO (29 Dec 1997) |
| endothelium-derived relaxing factor | A labile humoral agent released by the vascular endothelium that mediates the relaxation induced by some vasodilators such as acetylcholine and bradykinin. Edrf also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. These actions are believed to be mediated through stimulation of guanylate cyclase and the consequent elevation of cyclic guanosine 3',5'-monophosphate. Edrf is thought to be nitric oxide or a ready source of it. The factor is believed to be unstable and acts only locally in vivo. (12 Dec 1998) |
| acetosoluble albumin | A substance resembling serum albumin, but soluble in acetic acid. Synonym: acetosoluble albumin. (05 Mar 2000) |
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