| derepression | <genetics, molecular biology> Anything that stops the repression of a gene thereby allowing expression to occur. (18 Nov 1997) |
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| derepressed g. |
in genetic theory, one that in response to an environmental demand for a particular enzyme functions to increase production of that enzyme; cf. repressed g.
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| derepression |
removal of repression of an operon, so that gene transcription occurs or is enhanced. In prokaryotes, the mechanism involves inactivation of a repressor, either by inhibition of a corepressor or by the action of an inducer. In eukaryotes, the process appears to involve combinations of regulatory proteins and specific effectors, but has not been elucidated. The net result is frequently elevation of the level of a specific enzyme.
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