| deoxyribonucleases | <enzyme> Enzymes which catalyze the hydrolases of ester bonds within DNA. Registry number: EC 3.1.- (12 Dec 1998) |
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| deoxyribonucleases, type I site-specific | <enzyme> Enzyme systems containing three different subunits and requiring ATP, s-adenosylmethionine, and magnesium for endonucleolytic activity to give random double-stranded fragments with terminal 5'-phosphates. They function also as DNA-dependent atpases and modification methylases, catalyzing the reactions of EC 2.1.1.72 and EC 2.1.1.73 with similar site-specificity. The systems recognise specific short DNA sequences and cleave at sites remote from the recognition sequence. Enzymes from different microorganisms with the same specificity are called isoschizomers. Registry number: EC 3.1.21.3 (12 Dec 1998) |
| deoxyribonucleases, type II site-specific | <enzyme> Enzyme systems containing a single subunit and requiring only magnesium for endonucleolytic activity. The corresponding modification methylases are separate enzymes. The systems recognise specific short DNA sequences and cleave either within, or at a short specific distance from, the recognition sequence to give specific double-stranded fragments with terminal 5'-phosphates. Enzymes from different microorganisms with the same specificity are called isoschizomers. Registry number: EC 3.1.21.4 (12 Dec 1998) |
| deoxyribonucleases, type III site-specific | <enzyme> Enzyme systems composed of two subunits and requiring ATP and magnesium for endonucleolytic activity; they do not function as atpases. They exist as complexes with modification methylases of similar specificity. The systems recognise specific short DNA sequences and cleave a short distance, about 24 to 27 bases, away from the recognition sequence to give specific double-stranded fragments with terminal 5'-phosphates. Enzymes from different microorganisms with the same specificity are called isoschizomers. Registry number: EC 3.1.21.5 (12 Dec 1998) |
Synonyms : Acid DNase, Alkaline DNase, DNA Nucleases, DNase, Acid, DNase, Alkaline
Synonyms : DNase, Site Specific, Type I, Deoxyribonucleases, Type I, Site Specific, Deoxyribonucleases, Type I, Site-Specific, Site-Specific DNase, Type I, Type I Site Specific DNase, Type I Site Specific Deoxyribonucleases, Type I Site-Specific DNase
Synonyms : DNase, Site Specific, Type II, Deoxyribonucleases, Type II, Site Specific, Deoxyribonucleases, Type II, Site-Specific, Site-Specific DNase, Type II, Type II Site Specific DNase, Type II Site Specific Deoxyribonucleases, Type II Site-Specific DNase
Synonyms : DNase, Site Specific, Type III, Deoxyribonucleases, Type III, Site Specific, Deoxyribonucleases, Type III, Site-Specific, Site-Specific DNase, Type III, Type III Site Specific DNase, Type III Site Specific Deoxyribonucleases, Type III Site-Specific DNase
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