| Dmax | maximum denaturation; maximum diameter |
|---|---|
| EMT | emergency medical tag; emergency medical team; emergency medical technician; emergency medical treat... |
| HGM | hog gastric mucosa; human gene mapping; human glucose monitoring |
| BSPM | Body surface potential mapping |
|---|---|
| CFM | Color-flow mapping |
| SPM | Statistical Parametric Mapping |
| SPM96 | Statistical Parametric Mapping |
| CM | consistent mapping |
| alkali denaturation test | A test for haemoglobin F (Hb F), based on the fact that haemoglobins, with the exception of Hb F, are denatured by alkali to alkaline haematin; the test is sensitive to 2% or more Hb F. (05 Mar 2000) |
|---|---|
| nucleic acid denaturation | Disorganization of secondary structures of nucleic acids through cleavage of hydrogen bonds and hydrophobic linkages. Denatured DNA appears to be a single-stranded flexible structure. The effects of denaturation on RNA are similar though less pronounced and largely reversible. (12 Dec 1998) |
| denaturation | Reversible or irreversible loss of function in proteins and nucleic acids resulting from loss of higher order secondary, tertiary or quaternary structure) produced by nonphysiological conditions of pH, temperature, salt or organic solvents. (18 Nov 1997) |
| denaturation temperature of DNA | That temperature at which, under a given set of conditions, double-stranded DNA is changed (50%) to single-stranded DNA; under standard conditions, the base composition of the DNA can be estimated from the denaturation temperature, since the greater the denaturation temperature, the greater the guanine-plus-cytosine content (i.e., GC content) of the DNA. Synonym: melting temperature of DNA. (05 Mar 2000) |
| body surface potential mapping | Recording of regional electrophysiological information by analysis of surface potentials to give a complete picture of the effects of the currents from the heart on the body surface. It has been applied to the diagnosis of old inferior myocardial infarction, localization of the bypass pathway in wolff-parkinson-white syndrome, recognition of ventricular hypertrophy, estimation of the size of a myocardial infarct, and the effects of different interventions designed to reduce infarct size. The limiting factor at present is the complexity of the recording and analysis, which requires 100 or more electrodes, sophisticated instrumentation, and dedicated personnel. (12 Dec 1998) |
| cardiac mapping | A method by which local cardiac potentials are spatially depicted in an integrated manner as a function of time (isochrone map) or potential (isopotential map). (05 Mar 2000) |
| gene mapping | Determination of the relative positions of genes on a DNA molecule (chromosome or plasmid) and of the distance, in linkage units or physical units, between them. (09 Oct 1997) |
| mapping | See: gene mapping, linkage map, physical map. (09 Oct 1997) |
| mapping function | In linkage analysis, a formula that converts the recombination fraction (which is on the probability scale) into map distance (in morgans). (05 Mar 2000) |
| mapping, gene | Charting the positions of genes on chromosome and learning the distance, in linkage units or physical units, between genes. (12 Dec 1998) |
| genetic mapping | Determination of the relative positions of genes on a DNA molecule (chromosome or plasmid) and of the distance, in linkage units or physical units, between them. (14 Nov 1997) |
| restriction mapping | Use of restriction endonucleases to analyze and generate a physical map of genomes or genes. The nucleotide sequence determined is often then translated into an amino acid sequence, providing a means for sequencing the protein for which the gene codes, or for which the mRNA is a messenger. (12 Dec 1998) |
| peptide mapping | Two-dimensional separation and analysis of peptides. (12 Dec 1998) |
| chromosome mapping | The mapping of the relative locations of genes on a chromosome by analysing linkage frequencies (how often different genes are inherited together) and crossover frequencies (how often different combinations of three or more genes are inherited) or recombination frequencies. (09 Oct 1997) |
| S1 nuclease mapping | A method for locating the 5' end of a transcript in a mixture of RNA. (05 Mar 2000) |
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