| ¿µ¹® | bacteriophage | ÇÑ±Û | ¼¼±ÕÆÄÁö, ¹ÚÅ׸®¿ÀÆÄÁö |
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| DI | date of injury; defective interfering [particle]; dentinogenesis imperfecta; deoxyribonucleic acid i... |
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| DIPI | defective interfering particle induction |
| DLV | defective leukemia virus |
| L-variant | a defective bacterial variant that can multiply on hypertonic medium |
| L-[form] | a defective bacterial variant that can multiply on hypertonic medium |
| D RNA | defective RNA |
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| DI | Defective interfering |
| DIPs | Defective interfering particles |
| FDB | Familial Defective Apolipoprotein B-100 |
| FDB | Familial defective apo B-100 |
| defective bacteriophage | A temperate bacteriophage mutant whose genome does not contain all of the normal components and cannot become fully infectious virus, yet can replicate indefinitely in the bacterial genome as defective probacteriophage; many defective bacteriophage's are mediators of transduction. Synonym: defective phage. (05 Mar 2000) |
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| ventral nervous system defective | <molecular biology> A Drosophila gene encoding an integral membrane glycoprotein related to amyloidogenic glycoprotein. (12 Jan 1998) |
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| defective | Denoting or exhibiting a defect; imperfect; a failure of quality. (05 Mar 2000) |
| defective interfering particle | An incomplete virus that is unable to replicate and interferes with replication of an infectious virus. (05 Mar 2000) |
| defective organism | Mutant with a nutritional requirement not present in the wild type organism. Synonym: defective organism, deficiency mutant. (05 Mar 2000) |
| defective phage | A temperate bacteriophage mutant whose genome does not contain all of the normal components and cannot become fully infectious virus, yet can replicate indefinitely in the bacterial genome as defective probacteriophage; many defective bacteriophage's are mediators of transduction. Synonym: defective phage. (05 Mar 2000) |
| defective probacteriophage | See: defective bacteriophage. (05 Mar 2000) |
| defective prophage | A temperate bacteriophage mutant whose genome does not contain all of the normal components and cannot become fully infectious virus, yet can replicate indefinitely in the bacterial genome as defective probacteriophage; many defective bacteriophage's are mediators of transduction. Synonym: defective phage. (05 Mar 2000) |
| defective virus | <virology> A virus genetically deficient in replication, but that may nevertheless be replicated when it co-infects a host cell in the presence of a wild type helper virus. most acute transforming retroviruses are defective, since their acquisition of oncogenes seems to be accompanied by deletion of essential viral genetic information. (18 Nov 1997) |
| defective viruses | Viruses which lack a complete genome so that they cannot completely replicate or cannot form a protein coat. Some are host-dependent defectives, meaning they can replicate only in cell systems which provide the particular genetic function which they lack. Others, called satellite viruses, are able to replicate only when their genetic defect is complemented by a helper virus. (12 Dec 1998) |
| bacteriophage | <microbiology, virology> Viruses that have a specific affinity for and infect bacteria. The bacteriophages that attack Escherichia coli are termed coliphages, examples of these are lambda phage and the T even phages, T2, T4 and T6. Basically, phages consist of a protein coat or capsid enclosing the genetic material, DNA or RNA, that is injected into the bacterium upon infection. In the case of virulent phages all synthesis of host DNA, RNA and proteins ceases and the phage genome is used to direct the synthesis of phage nucleic acids and proteins using the host's transcriptional and translational apparatus. These phage components then self assemble to form new phage particles. The synthesis of a phage lysozyme leads to rupture of the bacterial cell wall releasing, typically 100-200 phage progeny. The temperate phages, such as lambda, may also show this lytic cycle when they infect a cell, but more frequently they induce lysogeny. The study of bacteriophages has been important for our understanding of gene structure and regulation. Lambda has been extensively used as a vector in recombinant DNA studies. (15 Nov 1997) |
| bacteriophage 2 depolymerase | <enzyme> Hydrolyzes glycolipoproteins and lipopolysaccharides; releases aminosugars Registry number: EC 3.2.1.- Synonym: phage 2 depolymerase (26 Jun 1999) |
| bacteriophage immunity | The state induced in a bacterium by lysogenization, the lysogenic bacterium being insusceptible to further lysogenization or to a lytic cycle by a superinfecting bacteriophage, in contradistinction to bacteriophage resistance. (05 Mar 2000) |
| bacteriophage lambda | <microbiology, virology> A bacteriophage, or virus which infects bacteria, that infects E. Coli. It has a complex set of regulatory mechanisms to determine whether it will quietly insert its DNA into the bacterial genome to become dormant and to be reproduced whenever the bacterium reproduces (to lysogenize), or whether it will hijack the bacterium's cellular machinery to reproduce itself and prepare to infect more bacteria, causing the bacterium to self-destruct shortly after infection (to lyse). Lambda is particularly useful to geneticists because parts of it can be used to introduce foreign DNA into the bacterial genome, it is a cloning vector. (09 Oct 1997) |
| bacteriophage m13 | <microbiology> A bacteriophage (a virus which infects bacteria) that has single-stranded DNA. It is used as a method of obtaining single strands of foreign DNA so that the foreign DNA can be sequenced (that is, the order of its nucleotide bases can be determined). It is also used in procedures to create mutations in vitro (in a test tube rather than within an organism). (09 Oct 1997) |
| bacteriophage mu | An unassigned species of temperate coliphage, in the family myoviridae, composed of a linear, double-stranded molecule of DNA, which is able to insert itself at random at any point on the host chromosome. It frequently causes a mutation by interrupting the continuity of the bacterial operon at the site of insertion. (12 Dec 1998) |
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