| 영문 | anaphylaxis | 한글 | 아나필락시스, 과민증 |
|---|---|---|---|
| 설명 | 아나필락시스라는 말은 제 1형 과민반응과 같은 말로 외계의 물질에 대한 면역 반응이 지나치게 항진되어 있는 병적인 상태를 말한다. 면역이란 외부물질에 대한 방어를 목적으로 하는 세포들의 활동을 의미하며, 여기에는 항체의 형성, 세포들의 포식작용(외부에서 들어온 물질을 면역기능을 하는 세포가 잡아먹는 것)등이 포함된다. 항체의 형성은 외부로부터 들어온 물질을 우선 큰포식세포 등이 포식을 하고 이것에 대한 정보를 T-림프구에게 전달하고 T-림프구는 이 정보를 처리하여 집약된 정보를 B-림프구에게 전달하며 이 세포로 하여금 그 물질 에 대한 항체를 생성하게 한다. 항체는 외부의 물질과 정확히 결합하여 외부의 물질의 활성화를 없애는 물질이다. 이렇게 형성된 항체중에서 IgE에 부착될 수 있는, 즉 이미 항체 IgE가 형성된(이렇게 되기 위해서는 그 물질이 이전에 한 번 몸속에 들어 왔어야 한다) 물질이 히스타민 등의 여러 물질이 나오게 되고 이런 물질들에 의해서 생기는 여러 가지 신체에 해로운 반응이 생겨난다. 그래서 필요 이상으로 과민한 이러한 형태의 면역작용을 거치는 반응을 아니필락시스라 한다. |
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| SRS-A | Slow Reacting Substance of Anaphylaxis |
|---|---|
| ASA | acetylsalicylic acid; active systemic anaphylaxis; Adams-Stokes attack; American Society of Anesthes... |
| BK-A | basophil kallikrein of anaphylaxis |
| ECFA, ECF-A | eosinophilic chemotactic factor of anaphylaxis |
| PAF-A | platelet-activating factor of anaphylaxis |
| ACA | Active cutaneous anaphylaxis |
|---|---|
| IA | Idiopathic Anaphylaxis |
| PCA | Passive Cutaneous Anaphylaxis |
| SRS-A | Slow Reacting Substance of Anaphylaxis |
| ASA | active systemic anaphylaxis |
| cytotropic | Having an affinity for cells. Synonym: cytophilic. (05 Mar 2000) |
|---|---|
| cytotropic antibody | Antibody that has an affinity for certain kinds of cells, in addition to and unrelated to its specific affinity for the antigen that induced it, because of the properties of the Fc portion of the heavy chain. See: heterocytotropic antibody, homocytotropic antibody, cytotropic antibody test. Synonym: anaphylactic antibody, cytophilic antibody. (05 Mar 2000) |
| cytotropic antibody test | A rosette test for macrophage cytotropic antibody: monolayers of macrophages are exposed first to antibody cytotropic for macrophages, then to the antigen (for which the antibody is specific), and indicator sheep erythrocytes; if the antibody is specific for sheep erythrocytes, the latter will form a rosette around the macrophages directly, but if not, and the antigen is soluble, the antigen must be coupled to the sheep erythrocytes by an agent such as bis-diazotised benzidine. (05 Mar 2000) |
| active anaphylaxis | Reaction following inoculation of antigen in a subject previously sensitised to the specific antigen, in contrast to passive anaphylaxis. (05 Mar 2000) |
| aggregate anaphylaxis | <pharmacology> As opposed to prophylaxis. A system or treatment that leads to damaging effects on the organism. <immunology> Now reserved for those inflammatory reactions resulting from combination of a soluble antigen with IgE bound to a mast cell that leads to degranulation of the mast cell and release of histamine and histamine like substances, causing localised or global immune reponses. Results in an acute allergic reaction with shortness of breath, rash, wheezing, hypotension. See: hypersensitivity. (18 Nov 1997) |
| anaphylaxis | <pharmacology> As opposed to prophylaxis. A system or treatment that leads to damaging effects on the organism. <immunology> Now reserved for those inflammatory reactions resulting from combination of a soluble antigen with IgE bound to a mast cell that leads to degranulation of the mast cell and release of histamine and histamine like substances, causing localised or global immune reponses. Results in an acute allergic reaction with shortness of breath, rash, wheezing, hypotension. See: hypersensitivity. (18 Nov 1997) |
| antiserum anaphylaxis | A reaction resulting from inoculation of antigen in an animal previously inoculated intravenously with specific antiserum from another animal, a latent period being required between the two inoculations. Synonym: antiserum anaphylaxis. (05 Mar 2000) |
| generalised anaphylaxis | The immediate response, involving smooth muscles and capillaries throughout the body of a sensitised individual, that follows intravenous (and occasionally intracutaneous) injection of antigen (allergen). See: anaphylactic shock. Synonym: systemic anaphylaxis. (05 Mar 2000) |
| passive anaphylaxis | A reaction resulting from inoculation of antigen in an animal previously inoculated intravenously with specific antiserum from another animal, a latent period being required between the two inoculations. Synonym: antiserum anaphylaxis. (05 Mar 2000) |
| passive cutaneous anaphylaxis | An evanescent cutaneous reaction occurring when antibody is injected into a local area on the skin and antigen is subsequently injected intravenously along with a dye. The dye makes the rapidly occurring capillary dilatation and increased vascular permeability readily visible by leakage into the reaction site. Pca is a sensitive reaction for detecting very small quantities of antibodies and is also a method for studying the mechanisms of immediate hypersensitivity. (12 Dec 1998) |
| passive cutaneous anaphylaxis test | An animal is injected intradermally with antibody (usually IgE) and subsequently challenged intravenously with a mixture of antigen and Evans blue dye 24-48 hours later. A dark blue area indicates a positive reaction due to the leakage of the dye at the site of antigen-antibody reactions. (05 Mar 2000) |
| reversed anaphylaxis | An anaphylactic reaction induced in an animal injected with a specific antigen, which will bind to reactive tissue, and then, after a latent period, with serum from another animal previously sensitised to the identical antigen. Synonym: reversed anaphylaxis. (05 Mar 2000) |
| reversed passive anaphylaxis | An anaphylactic reaction induced in an animal injected with a specific antigen, which will bind to reactive tissue, and then, after a latent period, with serum from another animal previously sensitised to the identical antigen. Synonym: reversed anaphylaxis. (05 Mar 2000) |
| pharmacologic mediators of anaphylaxis | Substances released from mast (and other) cells by the reaction of antigen and specific homocytotropic antibody on their surfaces; they include histamine, slow-reacting substance of anaphylaxis (SRS-A), bradykinin, and (in some species of animals) serotonin. (05 Mar 2000) |
| chronic anaphylaxis | A haemorrhagic and necrotizing inflammation developing in the ileum (and also the colon) of sensitised dogs when they are fed a second dose of the sensitizing material. Synonym: chronic anaphylaxis. (05 Mar 2000) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|