| ¿µ¹® | hypoxia | ÇÑ±Û | Àú»ê¼ÒÁõ |
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| ¼³¸í | »ê¼Ò¿î¹Ý°ú Ȱ¿ë °úÁ¤¿¡ Àå¾Ö¸¦ ¹ß»ýÇÏ¿©, µ¿¸ÆÇ÷ »ê¼ÒÇÔ·®(PaO2)ÀÌ °¨¼ÒÇϸç, Á¶Á÷ ¼ÓÀÇ »ê¼Ò°¡ Á¤»óÄ¡ ÀÌÇÏ·Î °¨¼ÒÇÑ »óÅÂ. ´ëº°ÇÏ¸é ¨ç Àú»ê¼Ò¼ºÀú»ê¼ÒÁõ, ¨è ºóÇ÷Àú»ê¼ÒÁõ, ¨é ¿ïÇ÷Àú»ê¼ÒÁõ, ¨ê Á¶Á÷µ¶¼ºÀú»ê¼ÒÁõ, ¨ë ¼ö¿ë¼º Àú»ê¼ÒÁõÀ» ºÐ·ùµÈ´Ù. ÃʱâÁõ»óÀº ÀǽÄÈ¥¶õ, µÎÅë, ¾îÁö·³Áõ, ±¸¿ª, °¡»Û È£Èí, ºü¸¥ ¸Æ µîÀ¸·Î, Áõ»óÀÌ ÁøÇàÇϸé û»öÁõ(Ç÷Áõ ȯ¿ø Hb °¡ 5g/100mL ÀÌ»ó), ÀǽļҽÇ, °æ·Ã, ´À¸°¸Æ, ºÎÁ¤¸Æ, È£Èí¾ïÁ¦, ½ÉÀåÁ¤Áö¿¡ À̸¥´Ù. »ê¼Ò¿ä¹ý, ±â°èÀû ÀΰøÈ£ÈíÀ» ½Ç½ÃÇÑ´Ù. ±× Á¾·ù¸¦ ¿øÀκ°·Î ºÐ·ùÇÏ¸é ´ÙÀ½°ú °°´Ù. ¨ç Àú»ê¼Ò¼ºÀú»ê¼ÒÁõ(hypoxic hypoxia): µ¿¸ÆÇ÷ÀÇ »ê¼ÒºÐ¾ÐÀÌ °¨¼ÒµÇ¾î ÃÊ·¡µÈ Àú»ê¼ÒÁõÀ¸·Î ÈíÀÔ °ø±â ÁßÀÇ »ê¼Ò ³óµµ°¡ °¨¼ÒÇÑ °æ¿ì, È£Èí ÁßÃß¾ïÁ¦-±âµµÆó¼â-È£Èí±Ù¸¶ºñ µî ÆóÆ÷ȯ±â°¡ °¨¼ÒÇÑ °æ¿ì, ¹«±âÆó-Æó·Å-ÆóºÎÁ¾ µî ÆóÆ÷¿¡¼ÀÇ °¡½º ±³È¯ÀÌ ºÎÀûÀýÇÏ¿© ÀϾ´Â °æ¿ì, °í¿-½ÅÁø´ë»çÇ×Áø µî Á¶Á÷ÀÇ »ê¼Ò ¼Ò¸ð°¡ Áõ°¡ÇÏ¿© ÀϾ´Â °æ¿ì, ÀÌ»êÈÁúÈ£(N2O)¸¦ ÀÌ¿ëÇÑ Àü½Å¸¶Ãë ÈÄ¿¡ µå¹°°Ô ³ªÅ¸³ª´Â È®»ê¼º Àú»ê¼ÒÁõ µî¿¡ ÀÇÇØ ¹ß»ýÇÒ ¼ö ÀÖ´Ù. ¨è ºóÇ÷Àú»ê¼ÒÁõ(anemic hypoxia) : Ç÷»ö¼Ò°¡ Á¤»ó ÀÌÇÏ·Î °¨¼ÒÇÑ °æ¿ì, ÀÏ»êÈ Åº¼ÒÁßµ¶Ã³·³ Ç÷»ö¼Ò°¡ »ê¼Ò¸¦ ¿î¹ÝÇÒ ¼ö ¾ø´Â °æ¿ì¿¡ ³ªÅ¸³ª´Â Àú»ê¼ÒÁõÀ¸·Î¼ »ê¼ÒºÐ¾ÐÀº Á¤»ó ¹üÀ§ ³»¿¡ ÀÖÀ¸³ª µ¿¸ÆÇ÷ÀÇ »ê¼Ò ÇÔ·®ÀÌ Å©°Ô °¨¼ÒµÇ¾î ÀÖ´Â °æ¿ì°¡ ´ëºÎºÐÀÌ´Ù. ¨é ¿ïÇ÷Àú»ê¼ÒÁõ(stagnant hypoxia) : µ¿¸ÆÇ÷ÀÇ »ê¼ÒºÐ¾ÐÀº Á¤»óÀ̳ª Á¶Á÷ÀÇ Ç÷¾×¼øÈ¯ÀÌ Àå¾Ö¸¦ ¹Þ¾Æ ³ªÅ¸³ª´Â Àú»ê¼ÒÁõÀ¸·Î ½É¹ÚÃâ·®ÀÌ °¨¼ÒÇÏ¿© ¿À´Â °æ¿ìµµ ÀÖ°í, »öÀüÁõ-¿Ü»ó-Ç÷°ü¼öÃà-Á¤¸ÆÆó¼â µî¿¡ ÀÇÇØ ¹ß»ýÇÒ ¼öµµ ÀÖ´Ù. ¨ê Á¶Á÷µ¶¼ºÀú»ê¼ÒÁõ(histotoxic hypoxia) : »ç¸³Ã¼ÀÇ »ê¼Ò ÀÌ¿ë·üÀÌ ³·¾ÆÁø °æ¿ì¿¡ ³ªÅ¸³´Ù. Ç÷°ü È®ÀåÁ¦¸¦ °ú·® »ç¿ëÇÏ°Ô µÇ¸é ¼¼Æ÷ ³» È¿¼ÒÀÇ µ¶¼º¿¡ ÀÇÇØ Àú»ê¼ÒÁõÀÌ ¿Ã ¼ö ÀÖ´Ù. |
||
| Tc cell | cytotoxic T cell |
|---|---|
| ACS | acrocallosal syndrome; acrocephalosyndactyly; acute chest syndrome; acute confusional state; Alcon C... |
| CA | anterior commissure [Lat. commissura anterior]; calcium antagonist; California [rabbit]; cancer; Can... |
| CI | cardiac index; cardiac insufficiency; cell immunity; cell inhibition; cephalic index; cerebral infar... |
| CL | capillary lumen; cardiolipin; cell line; centralis lateralis; chemiluminescence; chest and left arm ... |
| CH | Chronic hypoxia |
|---|---|
| H | Hypoxia |
| HYP | Hypoxia |
| HIF-1 | Hypoxia Inducible Factor-1 |
| HIF | Hypoxia inducible factor |
| antireticular cytotoxic serum | An antiserum specific for cells of the reticuloendothelial system. (05 Mar 2000) |
|---|---|
| cytotoxic | <pharmacology> Chemicals that are directly toxic to cells, preventing their reproduction or growth. Cytotoxic agents can, as a side effect, damage healthy, noncancerous tissues or organs which have a high proportion of actively dividing cells, for example, bone marrow, hair follicles. These side effects limit the amount and frequency of drug administration. (16 Dec 1997) |
| cytotoxic cell | Cells of the immune system that inhibit or help to terminate an immune response, e.g., suppressor macrophages and suppressor T-cells. Synonym: cytotoxic cell. (05 Mar 2000) |
| cytotoxic drugs | <pharmacology> Anti-cancer drugs which act by killing or preventing the division of cells. See: chemotherapy. (13 Nov 1997) |
| cytotoxic reaction | An immunologic (allergic) reaction in which noncytotropic IgG or IgM antibody combines with specific antigen on cell surfaces; the resulting complex initiates the activation of complement which causes cell lysis or other damage, or which, in the absence of complement, may lead to phagocytosis or may enhance T lymphocyte involvement. (05 Mar 2000) |
| cytotoxic T-cell | <haematology, immunology> Subset of T lymphocytes (mostly CD8) responsible for lysing target cells and for killing virus infected cells (in the context of Class I histocompatibility antigens). (18 Nov 1997) |
| cytotoxic t-lymphocyte | A type of CD8 or, less often, CD4 lymphocyte that kills diseased cells infected by a specific virus or other intracellular microbe. CTLs interact with MHC class I receptors (see Major Histocompatibility Complex). On infected cells and have the prime role in cellmediated immunity (see). Cytovene: See: Ganciclovir. (09 Oct 1997) |
| cytotoxic T lymphocyte-specific serine protease | <enzyme> Structural sequence given in first source Registry number: EC 3.4.21.- Synonym: cytotoxic t lymphocyte-specific serine protease ccp I, cytotoxic t lymphocyte specific serine protease ccp II, mast cell protease type II (26 Jun 1999) |
| T cytotoxic cells | Lymphocyte-like effector cells which mediate antibody-dependent cell cytotoxicity. They kill antibody-coated target cells which they bind with their fc receptors. (12 Dec 1998) |
| T-lymphocytes, cytotoxic | Immunised T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed lymphocyte cultures (mlc), in vivo during a graft-versus-host (gvh) reaction, or after immunization with an allograft, tumour cell or virally transformed or chemically modified target cell. The lytic phenomenon is sometimes referred to as cell-mediated lympholysis (cml). These cells are distinct from natural killer cells (killer cells, natural) and from killer cells mediating antibody-dependent cell cytotoxicity. (12 Dec 1998) |
| anaemic hypoxia | Hypoxia resulting from a decreased concentration of functional haemoglobin or a reduced number of erythrocytes; it is caused by haemorrhage or anaemia of various types, or by poisoning with CO2, nitrites, or chlorates. (05 Mar 2000) |
| cell hypoxia | A condition of decreased oxygen content at the cellular level. (12 Dec 1998) |
| cerebral hypoxia | A lack of oxygen to the cerebral hemispheres (the brain). Depending on the duration and extent of hypoxia, symptoms can be mild (for example lethargy) or serious neurologic damage can result (for example coma, seizures, death). (27 Sep 1997) |
| hypoxia | Reduction of oxygen supply to tissue below physiological levels despite adequate perfusion of the tissue by blood. (cf. Anoxia). (18 Nov 1997) |
| hypoxia-ischemia | See hypoxia. Ischemia refers to blood flow to cells and organs that is not sufficient to maintain their normal function. (12 Dec 1998) |
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