| CO | Cyclooxygenase |
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| cyclooxygenase | <enzyme> An enzyme protein complex present in most tissues that catalyses two steps in prostaglandin biosynthesis and produces prostaglandins and thromboxanes from arachidonic acid. The cyclooxygenase activity converts arachidonate and 2O2 to prostaglandin G2; the hydroperoxidase activity uses glutathione to convert prostaglandin G2 to prostaglandin H2. The cyclooxygenase activity is inhibited by aspirin like drugs, accounting for their anti-inflammatory effects. Synonym: prostaglandin endoperoxide synthase. (05 Mar 2000) |
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| cyclooxygenase inhibitor | <pharmacology> Compounds or agents that combine with cyclooxygenase (prostaglandin-endoperoxide synthase) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes. (08 Mar 2000) |
Synonyms : COX-1 Prostaglandin Synthase, Cyclo-Oxygenase I, Cyclooxygenase-1, COX 1 Prostaglandin Synthase, Cyclo Oxygenase I, Prostaglandin H Synthase 1, Prostaglandin Synthase, COX-1, Synthase, COX-1 Prostaglandin
Synonyms : COX-2 Prostaglandin Synthase, Cyclo-Oxygenase II, Cyclooxygenase-2, PGHS-2, PTGS2, Prostaglandin H Synthase-2, COX 2 Prostaglandin Synthase, Cyclo Oxygenase II, Prostaglandin H Synthase 2, Prostaglandin Synthase, COX-2, Synthase, COX-2 Prostaglandin
Synonyms : COX-2 Inhibitors, COX2 Inhibitors, Coxibs, Cyclooxygenase-2 Inhibitors, 2 Inhibitors, Cyclooxygenase, COX 2 Inhibitors, Inhibitors, COX-2, Inhibitors, COX2, Inhibitors, Cyclooxygenase 2, Inhibitors, Cyclooxygenase-2
Synonyms : Cyclo-Oxygenase Inhibitors, Inhibitors, Cyclo-Oxygenase, Inhibitors, Cyclooxygenase, Inhibitors, Prostaglandin Synthase, Inhibitors, Prostaglandin-Endoperoxide Synthase, Antagonists, Prostaglandin Synthesis, Cyclo Oxygenase Inhibitors
| cyclooxygenase |
either of two related enzymes that control the production of prostaglandins and are blocked by aspirin
Ãâó: wordnet.princeton.edu/perl/webwn
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| cyclooxygenase |
A prostaglandin endoperoxide synthase, COX enzymes are responsible for the production of prostaglandins, intracellular messengers found at high levels at inflammation sites. Of COX-1 and COX-2, the latter has received much attention due to drug development that has targeted COX-2 for selectively down regulating inflammatory processes.
Ãâó: www.jco.org/cgi/glossarylookup
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| cyclooxygenase |
The enzyme required for the conversion of fatty acids, such as arachidonic acid, to eicosanoids. Many anti-inflammatory drugs, such as aspirin, act by inactivating this enzyme. Omega-3 fatty acids react with cyclooxygenase enzyme to produce less harmful eicosanoids.
Ãâó: niazi.com/Omega/glossary.htm
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| cyclooxygenase | either of two related enzymes that control the production of prostaglandins and are blocked by aspirin |
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| cyclooxygenase | an enzyme that regulates prostaglandins that are important for the health of the stomach lining and kidneys |
| cyclooxygenase | an enzyme that makes prostaglandins that cause inflammation and pain and fever |
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