| Creutzfeld Jacob disease | <disease, virology> Rare fatal pre senile dementia of humans, similar to kuru and other slow viruses. Method of transmission unknown. Will induce neurological disorder in goats 3-4 years after inoculation with CJD brain extract. Classified pathologically as a subacute spongiform encephalopathy. See: Prions. (18 Nov 1997) |
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| Creutzfeldt, Hans Gerhard | <person> German neuropsychiatrist, 1885-1964. See: Creutzfeldt-Jakob disease, Jakob-Creutzfeldt disease. (05 Mar 2000) |
| creutzfeldt-jakob disease | <infectious disease> A very rare form of encephalopathy thought to be caused by a virus (slow-virus), termed a prion. There is little known about the mode of transmission. Human to human transmission has occurred through the use of contaminated brain electrodes and transplantation of infected tissues. The agent can be recovered in the CSF of infected individuals. Standard disinfectants such as formalin, heat, exposure to ultraviolet light or X-rays is ineffective to inactivate the virus. Autoclaving to at least 132 degrees C. Or immersion in 4% sodium hydroxide or 10% sodium hypochlorite solution for 1 hour is recommended for sterilisation. The disease occurs primarily in adults, with peak incidence in the late 50's. Infection results in dementia, myoclonus, ataxia and other neurologic symptoms. The disease progresses rapidly to coma and death after a 3 to 12 month illness. There is no known cure. (27 Sep 1997) |
| creutzfeldt-jakob syndrome | <syndrome> A rare, usually fatal, transmissible encephalopathy occurring in middle life, in which there is partial degeneration of the pyramidal and extrapyramidal systems accompanied by progressive dementia and sometimes muscle wasting, tremor, athetosis, and spastic dysarthria. A familial form has been shown to exhibit autosomal dominant inheritance. The more common sporadic form is probably caused by mutations that produce abnormal prion proteins (prions). A variant of cjd has been reported in patients younger than 30 years old, probably caused by exposure to beef harboring the bovine spongiform encephalopathy agent. (12 Dec 1998) |
Synonyms : CJD, CJD (Creutzfeldt-Jakob Disease), Creutzfeldt-Jakob Disease, Creutzfeldt-Jakob Disease, Familial, Creutzfeldt-Jakob Disease, New Variant, Familial Creutzfeldt-Jakob Disease, Jakob-Creutzfeldt Disease, Jakob-Creutzfeldt Syndrome, CJD Variant (V CJD)
| Creutzfeldt-Jakob disease |
rare (usually fatal) brain disease (usually in middle age) caused by an unidentified slow virus; characterized by progressive dementia and gradual loss of muscle control
출처: wordnet.princeton.edu/perl/webwn
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| Creutzfeldt-Jakob disease |
(Creutz
출처: www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspz...
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| Creutzfeldt-Jakob disease |
Creutzfeldt-Jakob Disease (CJD) is a very rare and incurable brain disease that is ultimately fatal. It is the most common of the transmissible spongiform encephalopathies (TSEs). TSEs (also known as prion diseases) are caused by a unique type of infectious agent called a prion, an abnormally-structured form of a protein found in the brain. ...
출처: en.wikipedia.org/wiki/Creutzfeldt-Jakob_disease
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| Creutzfeldt-Jakob disease |
A rare, ultimately fatal disorder of infectious or genetic origin that typically causes memory failure and behavioral changes. A recently identified form called
출처: www.alz.org/Resources/Glossary.asp
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| Creutzfeldt-Jakob disease |
(kroits ' felt - y?' k?) A disease (also known as "Classic CJD") that creates a protein plaque on the brain and eventually leads to a rapid death. It usually occurs in patients over the age of 60.
출처: www.bloodbook.com/glossary.html
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| creutzfeld | rare (usually fatal) brain disease (usually in middle age) caused by an unidentified slow virus |
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