| 영문 | coumarin | 한글 | 쿠마린 |
|---|---|---|---|
| 설명 | 혈액응고를 방해하는 약물. 혈액응고란 지혈의 한 과정으로 섬유소이라는 물질을 만들어 내는 과정이다. 이 섬유소라는 물질은 혈관의 손상된 부위에 작용하여 여러 가지 세포들을 얽혀 묶는 역할을 하여 결국 손상된 혈관에서 혈액의 소실을 막는다. 혈액응고에는 여러 가지 혈액응고인자가 관여하는데 이것들 중의 대부분은 간에서 비타민 K를 이용해서 생성된다. 이 쿠마린이란 약물은 간에서 비타민 K를 이용해서 생성되는 혈액응고인자의 생성을 억제하여 혈액응고가 일어나지 않게 하는 약물이다. 이 약물은 입으로 먹을 수가 있는 장점이 있지만, 복용후 약 1주일이 지나야 약물의 작용이 생기는 단점이 있다. |
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| DBH | Dopamine-Beta(β)-Hydroxylase |
|---|---|
| AHH | alpha-hydrazine analog of histidine; anosmia and hypogonadotropic hypogonadism [syndrome]; arylhydro... |
| DBH | dopamine beta-hydroxylase |
| PPH | past pertinent history; persistent pulmonary hypertension; phosphopyruvate hydratase; postpartum hem... |
| TH | tension headache; tetrahydrocortisol; T helper [cell]; theophylline; thorax; thrill; thyrohyoid; thy... |
| COH | Coumarin 7-hydroxylase |
|---|---|
| AFC | 7-amino-4-trifluoromethyl coumarin |
| ECDE | ethoxy-coumarin deethylase |
| C | coumarin |
| AHH | ARyl hydrocarbon hydroxylase |
| coumarin hydroxylase | <enzyme> Different preparations hydroxylate at position 3 and position 7; if cytochrome p-450coh is mutated at position 209, its substrate specificity is changed from coumarin hydroxylation to steroid hydroxylation Registry number: EC 1.14.99.- Synonym: cytochrome p-450coh, cytochrome p-4502a-5, cyp2a-5 gene product, coumarin 7-hydroxylase, cytochrome p-450 2a6, cyp2a6, cytochrome p-450 2a3, cyp2a3, p450 2a5, dhea hydroxylase, cyp2a5 (26 Jun 1999) |
|---|
| coumarin | <drug> O hydroxycinnamic acid. Pleasant smelling compound found in many plants and released on wilting (probably a major component of the smell of fresh hay). Has anticoagulant activity by competing with Vitamin K. (18 Nov 1997) |
|---|---|
| abscisic acid 8'-hydroxylase | <enzyme> Catalyses conversion of abscisic acid to 8'-hydroxyabscisic acid, which rearranges to phaseic acid Registry number: EC 1.14.99.- Synonym: aba 8'-hydroxylase (26 Jun 1999) |
| aflatoxin B1 hydroxylase | <enzyme> Hydroxylases may be replaced by mixed function oxidases as appropriate Registry number: EC 1.14.- Synonym: aflatoxin b1 4-hydroxylase (26 Jun 1999) |
| aklavinone 11-hydroxylase | <enzyme> A flavin-type bacterial hydroxylase from streptomyces peucetius; 489 amino acid residues, mw 52.3 kD; genbank u09844 Registry number: EC 1.14.14.- Synonym: dnrf protein, dnrf gene product (26 Jun 1999) |
| aniline hydroxylase | <enzyme> A drug-metabolizing, cytochrome p-450 enzyme which catalyses the hydroxylation of aniline to hydroxyaniline in the presence of reduced flavoprotein and molecular oxygen. Registry number: EC 1.14.14.- (12 Dec 1998) |
| arachidonic acid 18-hydroxylase | <enzyme> Converts arachidonic acid to 18-hydroxy-5,8,11,14-eicosatetraenoic acid in the presence of NADPH; cytochrome p450 enzyme Registry number: EC 1.14.13.- Synonym: arachidonic acid 18(r)-hydroxylase, arachidonic acid omega 3-hydroxylase (26 Jun 1999) |
| arylamine N-hydroxylase | <enzyme> Cytochrome p-448 dependent Registry number: EC 1.14.13.- Synonym: 2-aminofluorene n-hydroxylase (26 Jun 1999) |
| benzopyrene hydroxylase | <enzyme> A drug-metabolizing, cytochrome p-448 (p-450) enzyme which catalyses the hydroxylation of benzopyrene to 3-hydroxybenzopyrene in the presence of reduced flavoprotein and molecular oxygen. Also acts on certain anthracene derivatives. Registry number: EC 1.14.14.- (12 Dec 1998) |
| beta-carotene hydroxylase | <enzyme> O2-dependent NADPH-dependent monooxygenase from erwinia herbicola; forms zeaxanthin; amino acid sequence has been determined; genbank m87280 Registry number: EC 1.14.13.- Synonym: beta-carotene monooxygenase, crtz gene product (26 Jun 1999) |
| biphenyl-4-hydroxylase | <enzyme> Mixed function oxidase Registry number: EC 1.14.14.- (26 Jun 1999) |
| bufuralol 1'-hydroxylase | <enzyme> Liver microsomal enzyme utilizing NADPH and cytochrome p-450; competetive inhibition by debrisoquine Registry number: EC 1.14.99.- Synonym: bufuralol 1'-monooxygenase (26 Jun 1999) |
| bunitrolol 4-hydroxylase | <enzyme> Mediated by cytochrome p-450; catalyses the hydroxylation of bunitrolol Registry number: EC 1.14.99.- (26 Jun 1999) |
| camphor-6-exo-hydroxylase | <enzyme> A cytochrome p-450-dependent monooxygenase that catalyses the hydroxylation of camphor to 6-hydroxycamphor in sage and mycobacterium Registry number: EC 1.14.15.- (26 Jun 1999) |
| vanillate 1-hydroxylase | <enzyme> Catalyses the oxidative decarboxylation of vanillic acid to 2-methoxyhydroquinone Registry number: EC 1.14.13.- (26 Jun 1999) |
| geraniol 10-hydroxylase | <enzyme> Catalyses the conversion of geraniol to 10-hydroxygeraniol; a cytochrome p-450 enzyme Registry number: EC 1.14.- (26 Jun 1999) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|