| ¿µ¹® | corticosteroid | ÇÑ±Û | ÄÚ¸£Æ¼ÄÚ½ºÅ×·ÎÀ̵å |
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| ¼³¸í | ÄáÆÏÀ§¿¡ ÀÖ´Â »ï°¢»ÔÀÇ ÇüŸ¦ Áö´Ñ ±â°üÀÎ ºÎ½ÅÀÇ °ÑºÎºÐÀÎ °ÑÁú¿¡¼ ¸¸µé¾îÁö´Â ¹°Áú·Î È£¸£¸óÀÇ ÀÏÁ¾. ÄÚ¸£Æ¼°í½ºÅ×·ÎÀ̵å´Â ±× ¿ªÇÒ¿¡ µû¶ó¼ ´ÙÀ½°ú °°Àº 3°¡Áö·Î ³ª´©¾îÁø´Ù. 1.±Û·çÄÚÄÚ¸£Æ¼ÄÚÀ̵å(glucocorticoid)-Áö¹æÁú, ´çÁú, ´Ü¹éÁúÀÇ ´ë»ç¿¡ °ü°èÇϴ ȣ¸£¸ó. Áö¹æÁú°ú ´Ü¹éÁúÀ» ºÐÇØÇØ¼ ´çÁúÀ» ¸¸µå´Â ¿ªÇÒÀ» ÇÏ°í ¶Ç Ã¼³»¿¡ ÀúÀåµÇ¾î ÀÖ´Â ´çÁúÀ» Ç÷¾×¼ÓÀ¸·Î ¹èÃâÇÏ´Â ¿ªÇÒÀ» Çϴ ȣ¸£¸ó. ºÎ½Å°ÑÁú¿¡¼ ¸¸µé¾îÁö´Â ´ç·ùÄÚ¸£Æ¼ÄÚÀ̵å´Â ´ëºÎºÐ ÄÚ¸£Æ¼¼Ö(cortisol)À̶ó´Â ¹°ÁúÀÌ´Ù. 2.±¤¹°ÄÚ¸£Æ¼ÄÚÀ̵å(mineralocorticoid)-ü³»ÀÇ ÀüÇØÁú°ú ¼öºÐÀÇ Á¶Àý¿¡ °ü¿©Çϴ ȣ¸£¸ó. ÄáÆÏ¿¡ ÀÛ¿ëÇÏ¿© ¼öºÐ°ú ³ªÆ®·ýÀÇ ¹è¼³À» ¾ïÁ¦ÇÏ¿© ¼öºÐ, ³ªÆ®·ýÀÇ Ã¼³» ¾çÀ» Áõ°¡½ÃŰ´Â ¿ªÇÒÀ» ÇÑ´Ù. 3.¿¡½ºÆ®·Î°Õ, ¾Èµå·Î°Õ-¼ºÈ£¸£¸óÀ¸·Î ¼ºÀÇ ºÐȳª ¿©·¯ °¡Áö »ý½Ä¿¡ °ü·ÃµÈ ¿ªÇÒÀ» ÇÑ´Ù. ¾Ë¾ÆµÎ¾î¾ß ÇÒ °ÍÀº ºÎ½Å°ÑÁú¿¡¼ »ý»êµÈ À§ÀÇ 3°¡Áö È£¸£¸óÀº Á¤È®È÷ ±â´ÉÀÇ ±¸ºÐÀÌ ÀÖ´Â °ÍÀÌ ¾Æ´Ï°í ´Ù¸¥ È£¸£¸óÀÇ ÀÛ¿ëµµ °¡Áö°í ÀÖ´Â ¼ö°¡ ¸¹´Ù. Áï ±Û·çÄÚÄÚ¸£Æ¼ÄÚÀ̵嵵 ¾à°£ÀÇ ±¤¹°ÄÚ¸£Æ¼ÄÚÀ̵åÀÇ ¿ªÇÒÀÌ ÀÖ°í, ±¤¹°ÄÚ¸£Æ¼ÄÚÀ̵嵵 ¾à°£ÀÇ ±¤¹°ÄÚ¸£Æ¼ÄÚÀ̵åÀÇ ¿ªÇÒÀÌ ÀÖ´Ù. |
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| ¿µ¹® | thyroid hormone | ÇÑ±Û | °©»ó»ùÈ£¸£¸ó |
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| ¼³¸í | ±¤ÀÇÀÇ °©»ó¼±È£¸£¸óÀº Ƽ·Ï½Å(thyroxine(T4)), »ï¿äµåƼ·Î´Ñ(triiodothyronine (T3)), Ƽ·ÎÄ®½ÃÅä´Ñ(thyrocalcitonin)ÀÇ 3°¡ÁöÁß Çϳª¸¦ ¸»Çϳª ´ë°³ÀÇ °æ¿ì ÇùÀÇÀÇ ¶æÀ¸·Î »ç¿ëµÇ¸ç ÀÌ °æ¿ì Ƽ·Ï½Å°ú »ï¿äµåƼ·Î´ÑÀ» ÁöĪÇÑ´Ù. °©»ó¼± È£¸£¸óÀº °ÅÀÇ ¸ðµç ¸ö¼¼Æ÷¿¡¼ÀÇ ¹ÙÅÁÁú´ë»ç¿¡ °ü¿©ÇÏ¿© ¿¡³ÊÁö»ý¼ºÀ» Áõ°¡½ÃŰ°í ¼ºÀå ¹ßÀ°À» ÃËÁøÇÑ´Ù. À̰ÍÀº ³úÇϼöü¿¡¼ ºÐºñµÇ´Â °©»ó»ù ÀÚ±ØÈ£¸£¸ó¿¡ ÀÇÇØ ÇÕ¼º ¹× ºÐºñ°¡ ÃËÁøµÈ´Ù. ¼·ÃëÇÏ¿© ü³»¿¡ µé¾î¿Â ¿ä¿Àµå°¡ ´Éµ¿¿î¹Ý¿¡ ÀÇÇØ °©»ó»ù¼¼Æ÷³»·Î µé¾î°¡ ¼¼Æ÷³»¿¡ ÀÖ´Â ´Ü¹éÁúÀÎ °©»ó»ù ±Û·Îºí¸°°ú °áÇÕÇÏ¿© °©»ó»ùÈ£¸£¸óÀ¸·Î ÇÕ¼ºµÈ´Ù. ¿ä¿Àµå°¡ 3ºÐÀÚ °áÇÕÇÑ °ÍÀ» T3, 4ºÐÀÚ °áÇÕÇÑ °ÍÀ» T4¶ó ºÎ¸§. ºÐºñµÇ´Â °©»ó¼± È£¸£¸óÁß 90%ÀÌ»óÀÌ T4ÀÌ´Ù. Ç÷ÁßÀ¸·Î ºÐºñµÈ °©»ó»ùÈ£¸£¸óÀº Ç÷Áß ´Ü¹éÁú°ú °áÇÕÇϴµ¥ ´ëºÎºÐÀº Ƽ·Ð½Å°áÇÕ±Û·Îºí¸°°ú °áÇÕÇϸç ÀϺδ ¾ËºÎ¹Î°ú °áÇÕÇÑ´Ù. Àü¹ÝÀûÀÎ ´ë»çÀ²À» ÃËÁø½ÃŰ¸ç ¾î¸°ÀÌ¿¡¼´Â ¼ºÀåÀ» ÃËÁø½ÃŲ´Ù. ƯÈ÷ ¾î¸°ÀÌ¿¡¼ ¸ô´Ü¹éÁú ÇÕ¼ºÀ» ÃËÁøÇÏ¸ç ³úÀÇ ¹ß´Þ¿¡ Áß¿äÇÑ ±â´ÉÀ» ÇÔÀ¸·Î½á, ¼±Ãµ¼º °©»ó»ùÀúÇÏÁõ(cretinism)À» Á¶±â ¹ß°ßÇÏ¿© Ä¡·áÇÏÁö ¸øÇϸé Á¤½ÅÁöü°¡ À¯¹ßµÈ´Ù. °©»ó»ù°ú´ÙÁõÀÇ Áõ»óÀº ü³» ´ë»ç°¡ Ç×ÁøµÇ¾î ½Ä¿åÀÌ Áõ°¡Çϳª üÁßÀÌ °¨¼ÒÇÏ°í ½ÉÀå¹Úµ¿¼ö°¡ Áõ°¡ÇÏ°í ´õÀ§¸¦ ÂüÁö ¸øÇϸç, °©»ó»ù±â´ÉÀúÇÏÁõÀÇ Áõ»óÀº À§¿Í ¹Ý´ë·Î ½Ä¿åÀÌ °¨¼ÒÇϰí üÁßÀÌ Áõ°¡ÇÏ¸ç ½ÉÀå¹Úµ¿¼ö°¡ °¨¼ÒÇϰí ÃßÀ§¸¦ ÂüÁö ¸øÇϸç ÇǺο¡ ´Ü¹éÁúÀÌ ÃàÀûµÇ¾î Á¡¾×ºÎÁ¾ÀÌ À¯¹ßµÈ´Ù. |
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| ¿µ¹® | adrenocorticotropic hormone | ÇÑ±Û | ºÎ½Å°ÑÁúÀÚ±ØÈ£¸£¸ó |
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| ¼³¸í | ³úÇϼöü Àü¿±¿¡¼ ºÐºñµÇ¾î ºÎ½Å°ÑÁúÀ» ÀÚ±ØÇÏ´Â ´Ü¹é¼º È£¸£¸ó. ÇϼöüÀü¿°¿¡¼ ¸¸µé¾îÁ® ºÐºñµÇ´Â È£¸£¸óÀÌ´Ù. ºÎ½Å°ÑÁúÀÚ±Ø ÀÛ¿ëÀÌ ÀÖÀ¸¸ç ºÎ½Å°ÑÁúÁú¼¼Æ÷ÀÇ °æ¿ì¿¡ ½ºÅ×·ÎÀ̵åÈ£¸£¸ó »ýÇÕ¼ºÀÇ Á¶Àý´Ü°èÀÎ ÄÝ·¹½ºÅ׷ѷκÎÅÍÀÇ ÇÁ·¹±×³×·Ñ·Ð»ý¼ºÀ» ÃËÁøÇÑ´Ù. °áÁ¤±Û·çÄÚÄÚ¸£Æ¼ÄÚÀ̵忡 ÀÇÇØ ¹Ý´ëÀÇ µÇ¸ÔÀÓÁ¶Á¤À» ¹Þ´Â´Ù. ±Û·çÄÚÄÚ¸£Æ¼ÄÚÀ̵åÀÇ ÇϼöüÀü¿±¿¡ ´ëÇÑ Á÷Á¢ÀÛ¿ë°ú ½Ã»óÇϺÎÀÇ ºÎ½Å°ÑÁúÀÚ±ØÈ£¸£¸ó ¹æÃâÈ£¸£¸óÀ» ¸Åü·Î ÇÑ °£Á¢ÀÛ¿ëÀÌ ÀÖ´Ù. ¿©·¯ Á¾·ùÀÇ Á¤½ÅÀû À°Ã¼Àû ½ºÆ®·¹½º¿¡ ÀÇÇØ ºÐºñ°¡ ÀڱصȴÙ. |
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| ¿µ¹® | growth hormone | ÇÑ±Û | ¼ºÀåÈ£¸£¸ó |
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| ¼³¸í | ³úÇϼöü Àü¿±¿¡¼ ºÐºñµÇ´Â È£¸£¸óÁß Çϳª·Î¼ ½Ã»óÇϺÎÀÇ ¼ºÀåÈ£¸£¸ó¹æÃâ È£¸£¸ó¿¡ ÀÇÇØ ºÐºñ°¡ ÀÚ±ØµÇ¸ç ¼Ò¸¶Å佺Ÿƾ(somatostatin: ÀÌÀÚ¿¡¼ ºÐºñµÇ¸ç, ¼ºÀåÈ£¸£¸ó¿¡ ¹Ý´ëµÇ´Â ÀÛ¿ëÀ» ÇÔ)¿¡ ÀÇÇØ ºÐºñ°¡ ¾ïÁ¦µÈ´Ù. ¼ºÀå È£¸£¸ó ¹æÃâ È£¸£¸óÀº µµÆÄ¹Î(dopamine)À¸·Î ¾Ë·ÁÁ® ÀÖ´Ù. ¼ºÀå È£¸£¸óÀº ¼¼Æ÷ÀÇ ¼ºÀåÀ» ÃËÁø½Ã۸ç ƯÈ÷ °ñÀÇ ¼ºÀåÀ» ÀÚ±ØÇϴµ¥ ±× ÀÛ¿ëÀº Á÷Á¢ ¼¼Æ÷¿¡ ÀÛ¿ëÇÏ´Â °ÍÀÌ ¾Æ´Ï¶ó °£°ú ±ÙÀ°¿¡ ÀÛ¿ëÇÏ¿© ±×°÷¿¡¼ ¼Ò¸¶Åä¸ÞµòÀ» »ý¼ºÇϸç ÀÌ ¼Ò¸¶Åä¸ÞµòÀÌ ¼¼Æ÷ÀÇ ¼ºÀåÀ» ÃËÁø½ÃŲ´Ù. ÇÑÆí ¼ºÀå È£¸£¸óÀº ¼ºÀå¿¡ ÇÊ¿äÇÑ ´Ü¹éÁú ÇÕ¼ºÀ» Ç×Áø½ÃŰ°í ¿¡³ÊÁö´Â Áö¹æÀ» ÀÌ¿ëÇÏ¿© ¾ò°ÔÇϹǷΠÁö¹æÀÌ¿ëÈ£¸£¸óÀ̶ó°íµµ ºÒ¸°´Ù. ¼ºÀå È£¸£¸óÀÌ °ú´Ù ºÐºñµÇ¸é °ÅÀÎÁõ, ¸»´Üºñ´ëÁõÀÌ À¯¹ßµÇ¸ç ¼ºÀå È£¸£¸óÀÌ °áÇÌµÇ¸é ¼ºÀåºÎÁøÀÌ ¿Â´Ù. |
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| LHRH | Luteinizing Hormone Releasing Hormone ? GnRH; Gonadotropin Releasing Hormone &nbs... |
|---|---|
| FSH/LR-RH | follicle-stimulating hormone and luteinizing hormone releasing hormone |
| CMO | Corticosteroid Methyl-Oxidase |
| 17-OHCS | 17-OH(Hydroxy)-Corticosteroid |
| CBG | capillary blood gases; coronary bypass graft; corticosteroid-binding globulin; cortisol-binding glob... |
| 11-OHCS | 11-hydroxy-corticosteroid |
|---|---|
| 17-OHCS | 17-hydroxy-corticosteroid |
| C | Corticosteroid |
| CBG | Corticosteroid Binding Globulin |
| CR | Corticosteroid-resistant |
| corticosteroid | <drug, endocrinology, pharmacology> Any of the steroids elaborated by the adrenal cortex (excluding the sex hormones of adrenal origin) in response to the release of adrenocorticotrophin or adrenocorticotropic hormone (ACTH) by the pituitary gland, to any of the synthetic equivalents of these steroids or to angiotensin II. They are divided, according to their predominant biological activity, into three major groups: glucocorticoids (e.g. Cortisol, cortisone), chiefly influencing carbohydrate, fat and protein metabolism, mineralocorticoids (for example aldosterone), affecting the regulation of electrolyte and water balance and C19 androgens. Some corticosteroids exhibit both types of activity in varying degrees and others exert only one type of effect. The corticosteroids are used clinically for hormonal replacement therapy, for suppression of ACTH secretion by the anterior pituitary, as antineoplastic, antiallergic and anti-inflammatory agents and to suppress the immune response. Synonym: adrenocortical hormone, corticoid. (13 Nov 1997) |
|---|---|
| corticosteroid-binding globulin | <chemical> Chemical name: Transcortins (12 Dec 1998) |
| corticosteroid-binding protein | <chemical> Chemical name: Transcortins (12 Dec 1998) |
| corticosteroid cream | <drug, pharmacology> This is a large group of trade name medications that contain an anti-inflammatory steroid. These cream based medications all contain either hydrocortisone in varying concentrations or a synthetic steroid with much greater potency. This type of medications is useful in the treatment of a large number of inflammatory rashes. Caution: higher potency creams can cause side effects. Examples include hydrocortisone, dexamethasone, flunisolide, fluocinonide, fluprednisolone, Aclovate, Alphatrex, Aristocort, Betatrex, Cortone, Diprolene, Valisone, Halog, Hytone, Kenalog, Lidex, Lotrisone, Synalar, Synemol, Topicort, Vytone, Westcort and Vioform. (27 Sep 1997) |
| corticosteroid-induced acne | The exacerbation of acne after corticosteroid use is a common drug reaction seen in adolescents. Lessening the dose of the corticosteroid will often diminish this effect. (27 Sep 1997) |
| corticosteroid-induced glaucoma | <ophthalmology> Glaucoma caused by a hereditary predisposition in which local instillation of eyedrops containing corticosteroid causes increased intraocular pressure. (05 Mar 2000) |
| corticosteroid-induced striae | <dermatology> High-dose glucocorticoid therapy causes atrophy of the skin and a failure of the normal regenerative process. Purple striae often develop over the individual's trunk or thighs. The colour fades when the drug is stopped, but the dermal atrophy remains. (27 Sep 1997) |
| corticosteroid side-chain-isomerase | <enzyme> Converts 11-deoxycorticosterone to 20-hydroxy-3-oxypregn-4-en-21-al; also acts as an epimerase at c-20 Registry number: EC 5.3.1.21 Synonym: corticosteroid side chain isomerase, ccsci (26 Jun 1999) |
| receptors, pituitary hormone-regulating hormone | Cell surface receptors that bind the hypothalamic hormones regulating pituitary cell differentiation, proliferation, and hormone synthesis and release, including the pituitary-releasing and release-inhibiting hormones. The pituitary hormone-regulating hormones are also released by cells other than hypothalamic neurons, and their receptors also occur on non-pituitary cells, especially brain neurons, where their role is less well understood. Receptors for dopamine, which is a prolactin release-inhibiting hormone as well as a common neurotransmitter, are not included here. (12 Dec 1998) |
| growth hormone inhibiting hormone | <protein> Gastrointestinal and hypothalmic peptide hormone (two forms: 14 and 28 residues), found in gastric mucosa, pancreatic islets, nerves of the gastrointestinal tract, in posterior pituitary and in the central nervous system. Inhibits gastric secretion and motility: in hypothalamus/pituitary inhibits somatotropin release. (18 Nov 1997) |
| growth hormone-regulating hormone | <endocrinology> Hypothalamic hormones that induce (somatoliberin) or inhibit (somatostatin) the release of growth hormone (somatotropin). (18 Nov 1997) |
| growth hormone-releasing hormone | <endocrinology> Peptide hormone related to the glucagon family, released from the pituitary, acts on the adenohypophysis to release growth hormone. Synonym: somatoliberin, growth hormone-releasing factor. (20 Sep 2002) |
| hormones, hormone substitutes, and hormone antagonists | A collective grouping for both naturally occurring and synthetic hormones, substitutes, and antagonists. (12 Dec 1998) |
| follicle-stimulating hormone-releasing hormone | A decapeptide of hypothalamic origin capable of accelerating pituitary secretion of follitropin. Synonym: follicle-stimulating hormone-releasing factor, follicle-stimulating hormone-releasing hormone. Origin: follicle-stimulating hormone + L. Libero, to free, + -in (05 Mar 2000) |
| luteinizing hormone/follicle-stimulating hormone-releasing factor | gonadotrophin-releasing hormone |
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