| 영문 | mutation | 한글 | 돌연변이 |
|---|---|---|---|
| 설명 | 세포의 dna 자체의 변이에 의해 일어나는 세포변이를 말한다. 이러한 경우 돌연변이로 일어난 세포는 그 이후 딸세포(daughter cell)에서도 그 변이가 여전히 유지되므로 종(species)의 변화나, 혹은 세포의 악성변환(malignant transformation)에 관여한다. |
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| CTU | cardiac-thoracic unit; centigrade thermal unit; constitutive transcription unit |
|---|---|
| ARMS | adverse reaction monitoring system; amplification refractory mutation system |
| MF | magnetic field; meat free; medium frequency; megafarad; membrane filler; merthiolate-formaldehyde [s... |
| TFM | testicular feminization male; testicular feminization mutation; total fluid movement; transmission e... |
| ARMS | Amplification Refractory Mutation System |
|---|---|
| cNOS | Constitutive NO Synthase |
| cNO | constitutive NO |
| CTE | Constitutive Transport Element |
| cNOS | Constitutive nitric oxide synthase |
| constitutive | Constantly present, whether there is demand or not. Thus some enzymes are constitutively produced, whereas others are inducible. (18 Nov 1997) |
|---|---|
| constitutive enzyme | <enzyme> An enzyme that is constantly produced by the cell regardless of the growth conditions. Compare: induced enzyme. (05 Mar 2000) |
| constitutive gene | A gene which is continuously expressed without any regulation (transcription can be neither suppressed nor encouraged). These genes generally encode housekeeping functions and are expressed at low levels in all cells. (09 Oct 1997) |
| constitutive heterochromatin | <protein> Regions on chromosomes which are permanently condensed and genetically inactive in every cell in the body. The condensed portions are always in the same position on both homologous chromosomes. An example is the centromeres. Compare: facultative heterochromatin. (09 Oct 1997) |
| constitutive mutant | An organism with a mutation in a regulatory gene, so that the genes which its flawed regulatory product are supposed to suppress become constitutive genes, or impossible to turn off. Thus, the products of the uncontrolled genes are produced to excess. (09 Oct 1997) |
| acquired mutation | A change in a gene or chromosome that occurs in a single cell after the conception of the individual. That change is then passed along to all cells descended from that cell. Acquired mutations are involved in the development of cancer. (12 Dec 1998) |
| addition-deletion mutation | <molecular biology> A type of mutation that results from insertion or deletion of a single nucleotide into, or from, an open reading frame in the normal DNA sequence. Normally, the genetic code is read in the wrong frame, three nucleotides at a time, and the entire sequence downstream of the mutation, is translated into a polypeptide with a garbled amino acid sequence from the mutated codon onwards. These mutations may be induced by certain types of mutagens or may occur spontaneously and usually result in the generation, downstream, of nonsense, chain termination codons. Synonym: addition mutation, addition-deletion mutation, deletion mutation, reading-frameshift mutation. (21 Jun 2000) |
| addition mutation | <molecular biology> A type of mutation that results from insertion or deletion of a single nucleotide into, or from, an open reading frame in the normal DNA sequence. Normally, the genetic code is read in the wrong frame, three nucleotides at a time, and the entire sequence downstream of the mutation, is translated into a polypeptide with a garbled amino acid sequence from the mutated codon onwards. These mutations may be induced by certain types of mutagens or may occur spontaneously and usually result in the generation, downstream, of nonsense, chain termination codons. Synonym: addition mutation, addition-deletion mutation, deletion mutation, reading-frameshift mutation. (21 Jun 2000) |
| amber mutation | <molecular biology> A mutation from a codon which codes for an amino acid into the amber codon UAG, which normally signals that the translation of mRNA into an amino acid chain should stop. The mutation causes the amino acid chain to stop forming before it is actually completed. (09 Oct 1997) |
| back mutation | <molecular biology> A mutation that causes a mutant gene to revert to its original wild-type base sequence. Compare: forward mutation. (09 Oct 1997) |
| reading-frameshift mutation | <molecular biology> A type of mutation that results from insertion or deletion of a single nucleotide into, or from, an open reading frame in the normal DNA sequence. Normally, the genetic code is read in the wrong frame, three nucleotides at a time, and the entire sequence downstream of the mutation, is translated into a polypeptide with a garbled amino acid sequence from the mutated codon onwards. These mutations may be induced by certain types of mutagens or may occur spontaneously and usually result in the generation, downstream, of nonsense, chain termination codons. Synonym: addition mutation, addition-deletion mutation, deletion mutation, reading-frameshift mutation. (21 Jun 2000) |
| germinal mutation | A mutation in the germ cells (the cells which will undergo meiosis to form the gametes). Such mutations are therefore passed on to offspring. (09 Oct 1997) |
| germ-line mutation | Any detectable and heritable alteration in the lineage of germ cells. Mutations in these cells (i.e., "generative" cells ancestral to the gametes) are transmitted to progeny while those in somatic cells are not. (12 Dec 1998) |
| reverse mutation | <molecular biology> A mutation that causes a mutant gene to revert to its original wild-type base sequence. Compare: forward mutation. (09 Oct 1997) |
| chromosomal mutation | Can refer to any of a number of DNA mutations which results in a change in the protein encoded by the mutated gene, such as point mutations, insertion or deletion mutations (frameshift mutations), or nonsense mutations. More often this refers to mutations involving chromosomes, such as the inversion of part of one chromosome such that the inverted part no longer matches with its homologous pair, a translocation of one part of a chromosome to a different chromosome, deletions of parts of chromosomes, or accidents which happen during the division of the nucleus like the unequal portioning of chromosomes between the daughter cells. (09 Oct 1997) |
| constitutive mutation |
A mutation which causes transcription to be no longer under regulatory control.
출처: helios.bto.ed.ac.uk/bto/glossary/c2.htm
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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