| Tn | normal intraocular tension; transposon |
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| Tn5 | Transposon |
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| Tn | transposon |
| conjugative plasmid | Self-transmissible plasmid, a plasmid which encodes all the functions needed for its own intercellular transmission by conjugation. (09 Oct 1997) |
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| composite transposon | <molecular biology> A segment of DNA which contains the insertion elements at either end but can contain just about anything in the middle (genes, markers, etc.). These types of transposons tend to be very large, and many of them came about when the inner two insertion elements of two smaller transposons stopped working and only the two at the far ends continue to work, so that when the transposon moves, it takes everything in between the two original transposons with it. Some composite transposons are used in genetics experiments, Tn5 and Tn10 are two such composite transposons which have genes that encode resistance to certain antibiotics. (05 Jan 1998) |
| transposon | <molecular biology> Small, mobile DNA sequences that can replicate and insert copies at random sites within chromosomes. They have nearly identical sequences at each end, oppositely oriented (inverted) repeats and code for the enzyme, transposase, that catalyses their insertion. Bacteria have two types of transposon, simple transposons that have only the genes needed for insertion and complex transposons that contain genes in addition to those needed for insertion. Eukaryotes contain two classes of mobile genetic elements, the first are like bacterial transposons in that DNA sequences move directly. The second class (retrotransposons) move by producing RNA that is transcribed, by reverse transcriptase, into DNA which is then inserted at a new site. (13 Nov 1997) |
| transposon mutagenesis | <molecular biology> Insertion of a transposon into a gene, this inactivates the host gene leading to a mutant phenotype and also confers the phenotype associated with the transposon gene. (09 Oct 1997) |
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