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"congenital aplasia of thymus"¿¡ ´ëÇÑ °Ë»ö °á°úÀÔ´Ï´Ù. °Ë»ö °á°ú º¸´Â µµÁß¿¡ Tab ۸¦ ´©¸£½Ã¸é °Ë»ö âÀÌ ¼±Åõ˴ϴÙ.
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¿µ¹® thymus(gland) ÇÑ±Û °¡½¿»ù
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  °¡½¿ÀÇ ¾Õ À§ÂÊ¿¡ À§Ä¡ÇÑ ¸²ÇÁ¼º Àå±â·Î¼­, »çÃá±â¿¡ ÃÖ°íÀÇ ¹«°Ô¿¡ ´ÞÇß´Ù°¡ ÀÌÈÄ¿¡ ÅðÃàÇÑ´Ù. À̰ÍÀº ¼¼Æ÷¸Å°³ ¸é¿ª(cell-mediated immunity: ÁַΠT-¸²ÇÁ±¸¿¡ ÀÇÇØ ÀϾ¸ç, ÀÚ±â¿Í ´Ù¸¥ ¼¼Æ÷¿¡ ´ëÇÑ Àνİú À̽İźιÝÀÀ¿¡ °ü¿©ÇÔ)±â´ÉÀÇ ¹ß´Þ°ú ¼º¼÷¿¡ ÇÊ¿äÇÑ Àå±âÀ̸ç, È¸¹éÀû»öÀ¸·Î º¸Åë Á¤Á߸鿡¼­ °áÇÕÁ¶Á÷¿¡ ÀÇÇØ °áÇյȠµÎ °³ÀÇ ¿±À¸·Î µÇ¾î ÀÖ´Ù. °¡½¿»ùÀº »óÇǼ¼Æ÷, ¸²ÇÁ±¸, °¡½¿»ù¼¼Æ÷·Î ±¸¼ºµÇ¾î ÀÖÀ¸¸ç Àü±¸¼¼Æ÷°¡ °¡½¿»ù¿¡ ÀÌÇàÇÏ¿© ¸²ÇÁ±¸·Î ºÐÈ­µÇ°í, ±× ´ëºÎºÐÀº ÆÄ±«µÇ³ª ³ª¸ÓÁö´Â T¸²ÇÁ±¸¸¦ Çü¼ºÇÑ´Ù. °¡½¿»ùÀº ¶ÇÇѠȣ¸£¸ó À¯»ç¹°ÁúÀΠthymine, thymopoietin, thymosin µîÀ» ºÐºñÇÑ´Ù.
  
  
¿µ¹® congenital syphilis ÇÑ±Û ¼±Ãµ¸Åµ¶
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  ÀӺΰ¡ ¸Åµ¶¿¡ °¨¿°µÇ¾î ÀÖÀ¸¸é ÀӽŠÈı⿡ ¸Åµ¶±ÕÀ̠ŹÝÀ» ÅëÇØ Ç÷Ç༺À¸·Î Å¾ƿ¡ °¨¿°(¼öÁ÷°¨¿°)µÈ °ÍÀ» ¸»ÇÏ´Ù. ´ëºÎºÐÀº À¯»ê, »ç»êÀÌ µÇÁö¸¸ Ãâ»ýÇϸé Á¦2±â ÀÌÈÄÀÇ ¹ßÁøÀ» º¸ÀδÙ. ¹ßÇö½Ã±â¿¡ µû¶ó¼­ ¨ç Å¾Ƹŵ¶, ¨è À¯¾Æ¸Åµ¶, ¨é ¸¸¹ß¼º ¼±Ãµ¸Åµ¶À¸·Î ºÐ·ùµÈ´Ù. ¨ç¿¡¼­´Â »À¿¬°ñ¿°, °£-Áö¶ó ºñ´ë¿Í ¸Åµ¶¼º ÃµÆ÷â, ¨è¿¡¼­´Â ÆÄ·Î°¡¼º¸¶ºñ¿Í ¸Åµ¶¼º ÄÚ¿°, ¨é¿¡¼­´Â ÇãÄ£½¼ ¼¼Â¡ÈÄ(ÇãÄ£½¼ Ä¡¾Æ, ¼Ó±Í¼º ³­Ã», ½ÇÁú¼º °¢¸·¿°)¿¡ µû¶ó Æ¯Â¡ÀÌ ÀÖ´Ù. ±âŸ ¼öµÎÁõ, Áö´É¹ßÀ° ºÒ·® µîÀ» ÀÚÁÖ º¼ ¼ö ÀÖ´Ù. ¸Åµ¶ Ç÷û¹ÝÀÀÀº ´ëºÎºÐÀÇ °æ¿ì ¾ç¼ºÀ¸·Î ³ª¿Â´Ù. ¸Å¿ì µå¹°°Ô °£¼¼Æ÷³»¿¡¼­ ¸Åµ¶±ÕÀ» ¹«¼öÈ÷ º¼ ¼ö ÀÖ´Ù. °£¼¼Æ÷ ÁÖº¯ÀÇ ¼¶À¯È­¿Í ÇÔ²² ºÒ±ÔÄ¢ÇÑ ÈäÅÍ(hepar lobatum)¸¦ ¸¸µé ¼ö ÀÖ´Ù.
¿µ¹® congenital rubella syndrome ÇÑ±Û ¼±ÃµÇ³ÁøÁõÈıº
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  ÀӽűⰣ Áß¿¡ »ê¸ð°¡ Ç³Áø¿¡ °É¸®¸é À̠dzÁø ¹ÙÀÌ·¯½º´Â Å¹ÝÀ» ÅëÇØ¼­ Å¾ƿ¡°Ô Àü´ÞµÇ¾î¼­ Å¾ÆÀǠdzÁø°¨¿°À» ÀÏÀ¸Å²´Ù. ÀӽŠù 3°³¿ù µ¿¾È, Æ¯È÷ ÀӽŠù´Þ¿¡ Å¾ư¡ Ç³ÁøÀÇ °¨¿°À» ¹ÞÀ¸¸é, ½Å»ý¾Æ¿¡¼­ ¼±Ãµ±âÇü, Áï ´«¿¡¼­ ÃÐÁ¡À» Á¤È®È÷ ¸ÂÃß¾îÁִ ·»ÁîÀÇ ¿ªÇÒÀ» Çϴ ¼öÁ¤Ã¼ÀǠȥŹ(¹é³»Àå), ½ÉÀå±âÇü, ±Í¸Ó°Å¸® ¹× ½ÉÇÑ Áö´É¹Ú¾àÀ» µ¿¹ÝÇϴ ¼ÒµÎÁõ µîÀÌ ¹ß»ýÇϴ ¼ö°¡ ¸¹´Ù.
¿µ¹® congenital heart disease ÇÑ±Û ¼±Ãµ½ÉÀ庴
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  ¼±ÃµÀûÀ¸·Î ½ÉÀåÀÇ ±¸Á¶¿¡ ÀÌ»óÀÌ Àִ º´.
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  • ¿µ¹®
    ÇѱÛ
  • blood-thymus barrier
    Ç÷¾×°¡½¿»ùÀ庮, Ç÷¾×Èä¼±À庮
  • aplasia
    ¹«Çü¼º
  • aplasia cutis congenita
    ¼±ÃµÇǺι«Çü¼º
  • dental aplasia
    Ä¡¾Æ¹«Çü¼º
  • gonadal aplasia
    »ý½Ä»ù¹«Çü¼º
  • neocerebellar aplasia
    »õ¼Ò³ú¹«Çü¼º, ½Å¼Ò³ú¹«Çü¼º
  • red cell aplasia
    ÀûÇ÷±¸¹«Çü¼º
  • renal aplasia
    ÄáÆÏ¹«Çü¼º, ½ÅÀ幫Çü¼º
  • congenital
    ¼±Ãµ-
  • congenital adrenal hyperplasia
    ¼±ÃµºÎ½Å°ú´ÙÇü¼º, ¼±ÃµÄáÆÏÀ§»ù°ú´ÙÇü¼º
  • congenital amputation
    ¼±Ãµ¼ºÀý´Ü
  • congenital aural fistula
    ¼±Ãµ±Ó¹ÙÄû¾Õ»û±æ, ¼±ÃµÀÌÀüºÎ´©°ø
  • congenital bullous icthyosiform erythroderma
    ¼±Ãµ¹°Áýºñ´ÃÁõ¸ð¾çÈ«»öÇǺÎ(Áõ), ¼±Ãµ¼öÆ÷ºñ´ÃÁõ¸ð¾çÈ«»öÇǺÎ(Áõ)
  • congenital cataract
    ¼±Ãµ¹é³»Àå
  • congenital constriction band
    ¼±ÃµÇùÂø¶ì
´ëÇÑÀÇÇù Çʼö ÀÇÇпë¾îÁý »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 6 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • aplasia
    ¹«Çü¼º
  • thymus
    °¡½¿»ù
  • congenital cataract
    ¼±Ãµ¹é³»Àå
  • congenital heart disease
    ¼±Ãµ½ÉÀ庴
  • congenital adrenal hyperplasia
    ¼±ÃµºÎ½Å°ú´ÙÇü¼º, ¼±ÃµÄáÆÏÀ§»ù°ú´ÙÇü¼º
  • congenital megacolon
    ¼±Ãµ°Å´ëūâÀÚÁõ, ¼±Ãµ°Å´ë´ëÀåÁõ, ¼±Ãµ°Å´ë°áÀåÁõ
¿¾ ´ëÇÑÀÇÇù ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • aplasia
    ¹«Çü¼º
  • aplasia cutis congenita
    ¼±ÃµÇǺι«Çü¼º
  • dental aplasia
    Ä¡¾Æ¹«Çü¼º
  • gonadal aplasia
    »ý½Ä»ù¹«Çü¼º
  • neocerebellar aplasia
    »õ¼Ò³ú¹«Çü¼º
  • red cell aplasia
    ÀûÇ÷±¸¹«Çü¼º
  • renal aplasia
    ÄáÆÏ¹«Çü¼º
  • thymus-dependent antigen
    °¡½¿»ùÀÇÁ¸Ç׿ø
  • thymus-dependent area
    °¡½¿»ùÀÇÁ¸±¸¿ª
  • thymus-independent antigen
    °¡½¿»ùºñÀÇÁ¸Ç׿ø
  • thymus-independent area
    °¡½¿»ùºñÀÇÁ¸±¸¿ª
  • blood-thymus barrier
    Ç÷¾×°¡½¿»ùÀ庮
  • thymus-dependent cell
    °¡½¿»ùÀÇÁ¸¼¼Æ÷
  • thymus-derived cell
    °¡½¿»ùÀ¯·¡¼¼Æ÷
  • thymus-independent cell
    °¡½¿»ùºñÀÇÁ¸¼¼Æ÷
¿¾ ´ëÇÑÀÇÇù 2 ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • T cell ; T lymphocyte ; thymus derived lymphocyte
    T¼¼Æ÷ ; T¸²ÇÁ? ; Èä¼±À¯·¡¸²ÇÁ?
  • antigen, thymus-dependent
    Èä¼±ÀÇÁ¸Ç׿ø, °¡½¿»ùÀÇÁ¸Ç׿ø
  • antigen, thymus-independent
    Èä¼±ºñÀÇÁ¸Ç׿ø, °¡½¿»ùºñÀÇÁ¸Ç׿ø
  • antigen, thymus-leukemia
    Èä¼±-¹éÇ÷º´Ç׿ø, TLÇ׿ø
  • area, thymus-dependent
    Èä¼±ÀÇÁ¸¿ª, °¡½¿»ùÀÇÁ¸¿ª
  • DiGeorges syndrome => thymic-parathyroid aplasia
    µðÁÒÁö ÁõÈıº
  • Michels aplasia
    ¹Ìÿ ¹«Çü¼ºÁõ
  • germ cell aplasia
    »ý½Ä¼¼Æ÷Çü¼º °á¿©
  • germinal aplasia
    ¹è¹«Çü¼ºÁõ(ÛÏÙíû¡à÷ñø).
  • gonadal aplasia
    ¼º¼±¹«Çü¼ºÁõ(¡­Ùíû¡à÷ñø).
  • hereditary thymic aplasia
    À¯Àü¼º Èä¼±¹«Çü¼ºÁõ.
  • pure red cell aplasia
    (ÁøÁ¤)ÀûÇ÷±¸°è ¹«Çü¼º(Áõ)(¡­Ùíû¡à÷ñø).
  • pure red cell aplasia
    (ÁøÁ¤)ÀûÇ÷±¸°è ¹«Çü¼º(Áõ)((òØïá)îåúìϹͧ Ùíû¡à÷ñø)
  • red cell aplasia
    ÀûÇ÷±¸¹«Çü¼º
  • red cell aplasia
    ÀûÇ÷±¸¹«Çü¼º(îåúìϹÙíû¡à÷)
¿¾ ´ëÇÑÀÇÇù 3 ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • antigen, thymus-dependent
    Èä¼±ÀÇÁ¸Ç׿ø, °¡½¿»ùÀÇÁ¸Ç׿ø
  • antigen, thymus-independent
    Èä¼±ºñÀÇÁ¸Ç׿ø, °¡½¿»ùºñÀÇÁ¸Ç׿ø
  • antigen, thymus-leukemia
    Èä¼±-¹éÇ÷º´Ç׿ø, TLÇ׿ø
  • area, thymus-dependent
    Èä¼±ÀÇÁ¸¿ª, °¡½¿»ùÀÇÁ¸¿ª
  • blood thymus barrier
    Ç÷¾×°¡½¿»ùÀ庮, Ç÷Èä¼±À庮.
  • cell, thymus-dependent
    °¡½¿»ùÀÇÁ¸¼¼Æ÷, Èä¼±ÀÇÁ¸¼¼Æ÷
  • cell, thymus-derived
    °¡½¿»ùÀ¯·¡¼¼Æ÷, Èä¼±À¯·¡¼¼Æ÷
  • cortex of thymus
    °¡½¿»ù°ÑÁú
  • lobule of thymus
    °¡½¿»ù¼Ò¿±, Èä¼±(ýØàÍ)¼Ò¿±.
  • lobules of thymus
    °¡½¿»ù¼Ò¿±, Èä¼±(ýØàÍ)¼Ò¿±.
  • lobules of thymus
    °¡½¿»ù¼Ò¿±
  • medulla of thymus
    °¡½¿»ù¼ÓÁú
  • nodules of accessory thymus
    (µ¡°¡½¿»ù¼ÒÀý)
  • thymus
    Èä¼±, °¡½¿»ù
  • thymus
    Èä¼±(ýØàÍ)
´ëÇÑÇØºÎÇÐȸ ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 9 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • Congenital defect
    ¼±Ãµ°áÇÔ
    [¿¾ ¿ë¾î] ¼±Ãµ¼º°áÇÔ
  • Congenital glaucoma
    ¼±Ãµ³ì³»Àå
    [¿¾ ¿ë¾î] ¼±Ãµ¼º³ì³»Àå
  • Congenital metabolic defect
    ¼±Ãµ´ë»ç°áÇÔ
    [¿¾ ¿ë¾î] ¼±Ãµ¼º´ë»ç¼º°áÇÔ
  • Congenital cataract
    ¼±Ãµ¹é³»Àå
    [¿¾ ¿ë¾î] ¼±Ãµ¼º¹é³»Àå
  • (Nodules of accessory thymus)
    (µ¡°¡½¿»ù¼ÒÀý)
    [¿¾ ¿ë¾î] ºÎÈä¼±¼ÒÀý
  • Medulla of thymus
    °¡½¿»ù¼ÓÁú
    [¿¾ ¿ë¾î] Èä¼±¼öÁú
  • Cortex of thymus
    °¡½¿»ù°ÑÁú
    [¿¾ ¿ë¾î] Èä¼±ÇÇÁú
  • Lobules of thymus
    °¡½¿»ù¼Ò¿±
    [¿¾ ¿ë¾î] Èä¼±¼Ò¿±
  • THYMUS
    °¡½¿»ù
    [¿¾ ¿ë¾î] Èä¼±
´ëÇѱâ»ýÃæÇÐȸ ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 3 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • congenital infection
    ¼±Ãµ°¨¿°
  • congenital malaria
    ¼±Ãµ¸»¶ó¸®¾Æ
  • congenital toxoplasmosis
    ¼±ÃµÅå¼ÒÆ÷ÀÚÃæÁõ
´ëÇÑ»ýÈ­ÇкÐÀÚ»ý¹°ÇÐȸ ¿ë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 5 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • aplasia
    ¾ÆÇöóÁö¾Æ
  • congenital goiter
    "¼±Ãµ¼º °©»ó¼±Á¾(à»ô¸àõË£ßÒàÍðþ), (ÔÒ) =familial goiter"
  • congenital hyperammonemia
    ¼±Ãµ¼º(à»ô¸àõ) °ú(Φ)¾Ï¸ð´Ï¾ÆÇ÷Áõ(úìñø)
  • congenital parahemophilia
    ¼±Ãµ¼º ÃøÇ÷¿ìº´(à»ô¸àõö°úìéÒÜ»)
  • congenital porphyria
    ¼±Ãµ¼º(à»ô¸àõ) Æ÷¸£ÇǸ°Áõ(ñø)
KI ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 5 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
  • aplasia
    Çü¼ººÎÀüÁõ
  • congenital
    ¼±Ãµ¼ºÀÇ
  • persistent thymus
    Á¸¼ÓÈä¼±
  • T cell ¡ìthymus derived lymphocyte¡í
    T¼¼Æ÷ ¡ì Èä¼±À¯·¡ ¸²ÇÁ±¸¡í
  • thymus
    °¡½¿»ù, Èä¼±
KMLE ÀÇÇоà¾î »çÀü À¯»ç °Ë»ö °á°ú : 5 ÆäÀÌÁö: 1
TL temporal lobe; terminal limen; thermolabile; thermoluminescence; threat to life; thymus-leukemia [an...
MURCS Associations MUllerian duct aplasia, Renal aplasia, Cervico-thoracic vertebral(Somite) dysplasia Associations
CDH   1) Chronic Daily Headache
    = CTH
    = ...
CDH ceramide dihexoside; congenital diaphragmatic hernia; congenital dislocation of hip; congenital dysp...
TP temperature and pressure; temperature probe; temporal peak; temporoparietal; tension pneumothorax; t...
KMLE ÀÚµ¿ÃßÃâ ÀÇÇоà¾î »çÀü À¯»ç °Ë»ö °á°ú : 5 ÆäÀÌÁö: 1
ACC Aplasia cutis congenita
PRCA Pure Red Cell Aplasia
CT Calf thymus
CTL Cytotoxic thymus-derived lymphocytes
FTOC Fetal Thymus Organ Culture
°æºÏ´ë Ä¡°ú´ëÇÐ ±¸°­³»°ú ±³½Ç »çÀü À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
  • ¿µ¹®
    ÇѱÛ
    ¼³¸í
  • congenital aplasia
    ¼±Ãµ¼º ¹«Çü¼º, ¼±Ãµ¼º ¹«Çü¼ºÁõ
  • accessory thymus
    ºÎÈä¼±
    ¶§·Î´Â ¼±°ñÀÇ ³ôÀÌ¿¡¼­ º¼ ¼ö ÀÖ´Â Èä¼±ÀÇ ÀϺÎ. Èä¼±ÀÌ Çϰ­ÇÒ ¶§ ³²Àº °Í.
  • thymus
    °¡½¿»ù, Èä¼±
    1. È£¸£¸óÀ» ºÐºñÇÑ´Ù°í »ý°¢µÇ´Â ³»ºÐºñ¼±. 2. Á¾°Ýµ¿ÀÇ »óºÎ º¹Ãø¿¡ ÀÖ´Â ÀÙ ¸ð¾çÀÇ ¹èºÐºñ¼±À¸·Î À¯¾Æ±â¿¡ ÃÖ´ëÀÇ ¹ßÀ°À» ³ªÅ¸³»°í, ÁÂ¿ì ¾ç ¿±ÀÌ Á¤Áߺο¡¼­ À¯ÇÕÇÑ´Ù. ÇÇÁú°ú, ƯÀÌÀû ±¸Á¶ÀÎ Hassall ¼Òü¸¦ Æ÷ÇÔÇÏ´Â ¼öÁú·Î ÀÌ·ç¾îÁø´Ù.
  • thymus independent area
    Èä¼± µ¶¸³ºÎ, Èä¼± ºñÀÇÁ¸¿ª
    ºñÈä¼± ¸²ÇÁ±¸·Î ±¸¼ºµÈ ¸»ÃÊ ¸²ÇÁ ±â°üÀÇ ºÎºÐ.
  • thymus-dependent cell
    Èä¼± ÀÇÁ¸ ¼¼Æ÷
  • thymus-derived lymphocyte
    Èä¼± À¯·¡ Àӯı¸
  • aplasia
    ¹«Çü¼º, Çü¼ººÎÀü, Çü¼ººÎÀüÁõ, ¹«Çü¼ºÁõ, ¹ßÀ°ºÎÀü, ¹ßÀ°ºÎÀüÁõ
    ¹èÀÚ ¿ø±â
  • aplasia of spermatogenesis
    Á¤ÀÚ Çü¼º °á¿©, Á¤ÀÚ Çü¼º ±â´É °á¿©
  • dental aplasia
    Ä¡¾Æ ¹«Çü¼ºÁõ
    Ä¡¾Æ°¡ Çü¼ºµÇÁö ¾Ê´Â ¹ß»ý ÀÌ»óÁõ.
  • neocerebellar aplasia
    ½Å ¼Ò³ú ¹«Çü¼º
  • renal aplasia
    ½Å¹«Çü¼º, ½Å ¹«Çü¼ºÁõ
  • salivary gland aplasia
    Ÿ¾×¼± °á¼Õ
    ¸Å¿ì µå¹® °æ¿ì·Î Ÿ¾×¼±ÀÌ ¿ÏÀüÈ÷ °á¼ÕµÈ °æ¿ì·Î ´Ù¸¥ ¿Ü¹è¿±¼º ÀÌ»ó°ú µ¿¹ÝµÇ¾î ³ªÅ¸³ª´Â °æ¿ì°¡ ¸¹´Ù.
  • unilateral aplasia of tonsil
    ÆíÃø¼º Æíµµ¼± ¹«Çü¼º
  • vaginal aplasia
    Áú ¹«Çü¼º, Áú ¹«Çü¼ºÁõ
  • acyanotic congenital cardiopathy
    ºñû»ö¼º ¼±Ãµ ½Éº´Áõ, ºñû»ö¼º ¼±Ãµ ½ÉÀ庴Áõ
CancerWEB ¿µ¿µ ÀÇÇлçÀü ¸ÂÃã °Ë»ö °á°ú : 1 ÆäÀÌÁö: 1
congenital aplasia of thymus diGeorge syndrome
CancerWEB ¿µ¿µ ÀÇÇлçÀü À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 1
aplasia <embryology> A lack of development of an organ or tissue or of the cellular products from an organ or tissue.
Compare: hypoplasia.
Origin: Gr. Plassein = to form
(18 Nov 1997)
aplasia cutis congenita Congenital absence or deficiency of a localised area of skin, with the base of the defect covered by a thin translucent membrane; most often a single area near the vertex of the scalp, but may occur in other areas; underlying structures may also be affected; autosomal inheritance, either dominant or recessive.
(05 Mar 2000)
radial aplasia-thrombocytopenia syndrome <syndrome> Aplasia (absence) of the radius (the long bone on the thumb-side of the forearm) and thrombocytopenia (low blood platelets) are key features characterizing this syndrome. There is phocomelia (flipper-limb) with the thumbs always present. The fibula (the smaller bone in the lower leg) is often absent. The risk of bleeding from too few platelets is high in early infancy but lessens with age. The condition is inherited in an autosomal recessive trait with one gene (on a non-sex chromosome) coming from each parent to the child affected with the disease. Alternative names include thrombocytopenia-absent radius syndrome, tar syndrome, and tetraphocomelia-thrombocytopenia syndrome.
(12 Dec 1998)
germinal aplasia A disorder in which the seminiferous tubules exhibit an abnormal cytoarchitecture and extensive hyalinization; the testes are small, and few spermatozoa are formed; the body habitus may be eunuchoid, and gynaecomastia may be present; urinary gonadotropin output is usually high, and the incidence of mental deficiency and illness increased; sex chromatin may be male or female, and androgen secretion ranges from subnormal to normal. It is a constant feature of (and is often used synonymously with) Klinefelter's syndrome.
Synonym: germinal aplasia.
(05 Mar 2000)
red-cell aplasia, pure Suppression of erythropoiesis with little or no abnormality of leukocyte or platelet production.
(12 Dec 1998)
gonadal aplasia Congenital absence of essentially all gonadal tissue; the external genitalia and genital ducts are female, but if interstitial cells of Leydig are present, the external genitalia are commonly ambiguous and the genital ducts are female.
See: gonadal dysgenesis.
Compare: Klinefelter's syndrome, Turner's syndrome.
Synonym: gonadal agenesis.
(05 Mar 2000)
pure red cell aplasia A transitory arrest of red blood cell production which may occur in the course of a haemolytic anaemia, often preceded by infection, or as a complication of certain drugs; if the arrest persists anaemia may result.
See: congenital hypoplastic anaemia.
(05 Mar 2000)
syndrome, radial aplasia-thrombocytopenia See syndrome, tar.
(12 Dec 1998)
thymic aplasia <disease, immunology> A lack of T lymphocytes, due to failure of the thymus to develop, resulting in very reduced cell-mediated immunity though serum immunoglobulin levels may be normal.
See: DiGeorge syndrome.
Origin: Gr. Plassein = to form
(18 Nov 1997)
ribonuclease h, calf thymus <enzyme> A ribonuclease that specifically cleaves the RNA moiety of RNA:DNA hybrids. It has been isolated from a wide variety of prokaryotic and eukaryotic organisms (particularly calf thymus) as well as retroviruses.
Registry number: EC 3.1.26.4
(12 Dec 1998)
cortex of thymus The outer part of a lobule of the thymus; it surrounds the medulla and is composed of masses of closely packed lymphocytes.
(05 Mar 2000)
hypoplasia of the thymus and parathyroids Also known as the digeorge syndrome (dgs), this disorder is characterised by (1) low blood calcium levels (hypocalcaemia) due to underdevelopment (hypoplasia) of the parathyroid glands needed to control calcium; (2) underdevelopment (hypoplasia) of the thymus, an organ behind the breastbone in which lymphocytes mature and multiply; and (3) defects of the outflow tracts from the heart. most cases of dgs are due to a microdeletion in chromosome band 22q11.2. A small number of cases have defects in other chromosomes, notably 10p13. Named after the american paediatric endocrinologist angelo digeorge. Another name for dgs is the third and fourth pharyngeal pouch syndrome (since the faulty structures in dgs are embryologically derived from the third and fourth pharyngeal pouches).
(12 Dec 1998)
thymus <anatomy> The lymphoid organ in which T lymphocytes are educated, mature and multiply. It is composed of stroma (thymic epithelium) and lymphocytes, almost entirely of the T-cell lineage. In mammals the thymus is just anterior to the heart within the rib cage, in other vertebrates in rather undefined regions of the neck or within the gill chamber in teleost fish. The thymus regresses as the animal matures.
(18 Nov 1997)
thymus and parathyroids, hypoplasia of See third and fourth pharyngeal pouch syndrome.
(12 Dec 1998)
thymus-dependent zone <anatomy> Mid cortical region of lymph node, area that is particularly depleted of T lymphocytes in thymectomised animals and is referred to as the thymus dependent area.
(18 Nov 1997)
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