| 영문 | mutation | 한글 | 돌연변이 |
|---|---|---|---|
| 설명 | 세포의 dna 자체의 변이에 의해 일어나는 세포변이를 말한다. 이러한 경우 돌연변이로 일어난 세포는 그 이후 딸세포(daughter cell)에서도 그 변이가 여전히 유지되므로 종(species)의 변화나, 혹은 세포의 악성변환(malignant transformation)에 관여한다. |
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| 영문 | virus | 한글 | 바이러스 |
|---|---|---|---|
| 설명 | 박테리아보다 덜 진화된, 생물과 무생물의 중간단계에 해당하는 것. 혼자서는 생존능력이 없으므로 반드시 다른 세포내에 속해 있어야 한다. 인체에 발생하는 많은 병중, 이 바이러스로 인해 발생하는 경우가 많으며, 이 때 대부분 특이한 치료법은 없는 실정이다. 일부 헤르페스바이러스 계통에는 치료약이 개발되어 있지만, 이것도 일부 질병에서만 치료가 가능하다. 또한, Ebstein-Barr virus, Human papilloma virus 등은 암의 발생과 연관되어 있으며, 동물에서 발생하는 대부분의 암종은 바이러스와 연관되어 있는 경우가 많다. 요즘, 일부 지역에서 큰 유행을 하고 있는 후천성면역결핍증후군(AIDS)도 HIV(Human Immunodeficiency Virus)와 관련이 있다. |
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| 영문 | simian virus | 한글 | 원숭이바이러스 |
|---|---|---|---|
| 설명 | 원숭이에서 분리된 바이러스. 아데노바이러스, 엔테로바이러스, 헤르페스바이러스 및 레오바이러스 등의 여러 군에 속한다. |
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| 영문 | influenza virus | 한글 | 인플루엔자바이러스 |
|---|---|---|---|
| 설명 | 인플루엔자의 병원체. 상기도 점막에 침입하여 호흡기 질환을 일으킨다. 보체 결합 항원의 차이에 따라 A-B-C 세형태로 나뉘며, 유행할 때마다 혈구 응집 항원이 변이하여 광범위한 유행을 나타낸다. 껍질이 있는 80~150nm의 공모양, 나선 대칭 RNA 바이러스이다. 두 종류의 스파이크, 뉴라미니다아제(neuraminidase, NA), 당단백질과 헤마글루티닌(hemagglution, HA) 당단백질을 만든다. A형의 NA에는 N1-N2의 두 종류, HA에는 HAO-HA1-HA2-HA3의 네 종류가 있다. A형은 말-돼지-새에 감염하며 새로운 아형은 동물 바이러스와의 조환형이며, 그 밖에 동일 아형내 점변이가 있다. B, C형은 사람 이외에는 감염되지 않는다. 닭의 적혈구를 응집하는 성질이 있다. 바이러스 진단에는 환자의 인두 세척액에서 분리한다든가, 또는 환자의 혈청항체에 의한 특이적 적혈구 응집저지검사, 뉴라미니다아제 활성저지검사 또는 중화검사 등으로 검출한다. |
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| ARMS | adverse reaction monitoring system; amplification refractory mutation system |
|---|---|
| MF | magnetic field; meat free; medium frequency; megafarad; membrane filler; merthiolate-formaldehyde [s... |
| TFM | testicular feminization male; testicular feminization mutation; total fluid movement; transmission e... |
| FACA | Fanconi anemia complementation group A; Fellow of the American College of Anesthetists; Fellow of th... |
| FACB | Fanconi anemia complementation group B |
| XP-A | Xeroderma Pigmentosum complementation group A |
|---|---|
| CG | complementation group |
| XP-C | xeroderma pigmentosum complementation group C |
| ARMS | Amplification Refractory Mutation System |
| MFD | Mutation frequency decline |
| genetic complementation | <genetics> The reappearance of wild-type characteristics in a cell or organism that has had two distinct mutations on the same chromosome. Two normal versions of two different mutant genes on different chromosomes affecting the same phenotype which, when inherited together, results in the wild-type phenotype despite the presence of mutant copies of the genes. (09 Oct 1997) |
|---|---|
| genetic complementation test | A test used to determine whether or not complementation (compensation in the form of dominance) will occur in a cell with a given mutant phenotype when another mutant genome, encoding the same mutant phenotype, is introduced into that cell. (12 Dec 1998) |
| complementation | <cell biology> The ability of a mutant chromosome to restore normal function to a cell that has a mutation in the homologous chromosome when a hybrid or heterokaryon is formed the explanation being that the mutations are in different cistrons and between the two a complete set of normal information is present. (18 Nov 1997) |
| complementation-fixation test | <investigation> A test for the presence of antibodies in a serum, based on whether an antigen and complement, when put together with some red blood cells, are able to destroy them. If the red blood cells are destroyed, then antibodies were not present to prevent it. If the red blood cells are not destroyed, then antibodies were present to combine with the antigen and bind the complement, making them unable to attack the red blood cells. (09 Oct 1997) |
| intergenic complementation | Complementation between pieces of genetic material that regulate the same function, such as a multienzyme pathway, but have defects in regions of separate genetic function; such complementation permits synthesis of a normal end-product. (05 Mar 2000) |
| intragenic complementation | Complementation between pieces of genetic material, each of which has a different defect within the same locus; the resultant product of each is defective and nonfunctional, but the defective products may associate to produce a product which has some activity. (05 Mar 2000) |
| acquired mutation | A change in a gene or chromosome that occurs in a single cell after the conception of the individual. That change is then passed along to all cells descended from that cell. Acquired mutations are involved in the development of cancer. (12 Dec 1998) |
| addition-deletion mutation | <molecular biology> A type of mutation that results from insertion or deletion of a single nucleotide into, or from, an open reading frame in the normal DNA sequence. Normally, the genetic code is read in the wrong frame, three nucleotides at a time, and the entire sequence downstream of the mutation, is translated into a polypeptide with a garbled amino acid sequence from the mutated codon onwards. These mutations may be induced by certain types of mutagens or may occur spontaneously and usually result in the generation, downstream, of nonsense, chain termination codons. Synonym: addition mutation, addition-deletion mutation, deletion mutation, reading-frameshift mutation. (21 Jun 2000) |
| addition mutation | <molecular biology> A type of mutation that results from insertion or deletion of a single nucleotide into, or from, an open reading frame in the normal DNA sequence. Normally, the genetic code is read in the wrong frame, three nucleotides at a time, and the entire sequence downstream of the mutation, is translated into a polypeptide with a garbled amino acid sequence from the mutated codon onwards. These mutations may be induced by certain types of mutagens or may occur spontaneously and usually result in the generation, downstream, of nonsense, chain termination codons. Synonym: addition mutation, addition-deletion mutation, deletion mutation, reading-frameshift mutation. (21 Jun 2000) |
| amber mutation | <molecular biology> A mutation from a codon which codes for an amino acid into the amber codon UAG, which normally signals that the translation of mRNA into an amino acid chain should stop. The mutation causes the amino acid chain to stop forming before it is actually completed. (09 Oct 1997) |
| back mutation | <molecular biology> A mutation that causes a mutant gene to revert to its original wild-type base sequence. Compare: forward mutation. (09 Oct 1997) |
| reading-frameshift mutation | <molecular biology> A type of mutation that results from insertion or deletion of a single nucleotide into, or from, an open reading frame in the normal DNA sequence. Normally, the genetic code is read in the wrong frame, three nucleotides at a time, and the entire sequence downstream of the mutation, is translated into a polypeptide with a garbled amino acid sequence from the mutated codon onwards. These mutations may be induced by certain types of mutagens or may occur spontaneously and usually result in the generation, downstream, of nonsense, chain termination codons. Synonym: addition mutation, addition-deletion mutation, deletion mutation, reading-frameshift mutation. (21 Jun 2000) |
| germinal mutation | A mutation in the germ cells (the cells which will undergo meiosis to form the gametes). Such mutations are therefore passed on to offspring. (09 Oct 1997) |
| germ-line mutation | Any detectable and heritable alteration in the lineage of germ cells. Mutations in these cells (i.e., "generative" cells ancestral to the gametes) are transmitted to progeny while those in somatic cells are not. (12 Dec 1998) |
| reverse mutation | <molecular biology> A mutation that causes a mutant gene to revert to its original wild-type base sequence. Compare: forward mutation. (09 Oct 1997) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|