| 영문 | collagen | 한글 | 아교질, 콜라젠 |
|---|---|---|---|
| 설명 | 결합조직의 세포의 기질을 구성하는 주요한 섬유성 단백질이다. 사람에서는 생체의 전체단백질의 약 30%를 차지한다. 분자량 30~35만, 구성아미노산으로서 글리신과 프롤린이 많고 함유아미노산이 적다. 특유 아미노산으로서 히드록시프롤린과 히드록시리신을 포함한 특이한 아미노산 조성을 나타내며 분자내에 연속되는 Gly-Pro-X의 되풀이 구조를 갖는다. 분자구조의 다름에 따라 I~VIII형으로 분류되지만 요즘 더욱 새로운 분자형이 보고되고 있다. 조직형태의 골격구조의 유지, 각종세포의 흡착, 세포의 분화-증식 등에 관여하는 외에 경조직의 석회화에 있어서의 바탕질로서 중요한 역할을 한다. |
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| bHLH | basic helix-loop-helix |
|---|---|
| bHLH-ZIP | basic helix-loop-helix-leucine zipper |
| HLH | helix-loop-helix; hemophagocytic lymphohistiocytosis |
| HD | Haab-Dimmer [syndrome]; Hajna-Damon [broth]; Hansen disease; hearing distance; heart disease; helix ... |
| HPA | Health Care Practice Act; Health Policy Agenda for the American People; health promotion advocates; ... |
| HLH | B)-helix-loop-helix |
|---|---|
| bHLH | Basic Helix-Loop-Helix |
| bHLH | Basic region helix-loop-helix |
| H-T-H | helix-turn-helix |
| HhH | Helix-hairpin-Helix |
| helix loop helix | <molecular biology> A motif associated with transcription factors, allowing them to recognise and bind to specific DNA sequences. Two _ helices are separated by a loop. Examples: myoblast MyoD1, c myc, Drosophila genes daughterless, hairy, twist, scute, achaete, asense. Not the same as helix turn helix. (18 Nov 1997) |
|---|---|
| helix-loop-helix motifs | A group of 20-residue peptides characterised by two alpha helices separated by a non-helical segment. These recurring supersecondary structural patterns are found in many sequence-specific DNA-binding proteins. (12 Dec 1998) |
| helix turn helix | <molecular biology> A motif associated with transcription factors, allowing them to bind to and recognise specific DNA sequences. Two amphipathic _ helices are separated by a short sequence with a _ sheet. One helix lies across the major groove of the DNA, while the recognition helix enters the major groove and interacts with specific bases. An example in Drosophila is the homeotic gene fushi tarazu, that binds to the sequence TCAATTAAATGA. Not the same as helix loop helix. (18 Nov 1997) |
| helix-turn-helix motifs | The first DNA-binding protein motif to be recognised. Helix-turn-helix motifs were originally identified in bacterial proteins but have since been found in hundreds of DNA-binding proteins from both eukaryotes and prokaryotes. They are constructed from two alpha helices connected by a short extended chain of amino acids, which constitute the "turn." the two helices are held at a fixed angle, primarily through interactions between the two helices. (12 Dec 1998) |
| Mallory's collagen stain | <technique> One of a number of staining methods using phosphomolybdic or phosphotungstic acid with an acid stain, such as aniline blue, or with haematoxylin for connective tissue staining. (05 Mar 2000) |
| collagen | <protein> The protein substance of the white fibres (collagenous fibres) of skin, tendon, bone, cartilage and all other connective tissue, composed of molecules of tropocollagen, it is converted into gelatin by boiling. Collagenous pertaining to collagen, forming or producing collagen. Origin: Gr. Kolla = glue, gennan = to produce (18 Nov 1997) |
| collagen diseases | Historically, a heterogeneous group of acute and chronic diseases, including rheumatoid arthritis, systemic lupus erythematosus, progressive systemic sclerosis, dermatomyositis, etc. This classification was based on the notion that "collagen" was equivalent to "connective tissue", but with the present recognition of the different types of collagen and the aggregates derived from them as distinct entities, the term "collagen diseases" now pertains exclusively to those inherited conditions in which the primary defect is at the gene level and affects collagen biosynthesis, post-translational modification, or extracellular processing directly. (12 Dec 1998) |
| collagen fibre | An individual fibre that varies in diameter from less than 1 um to about 12 um and is composed of fibrils; the fibre's, which are usually arranged in bundles, undergo some branching and are of indefinite length; chemically the fibre is a glycoprotein, collagen, which yields gelatin upon boiling; they make up the principal element of irregular connective tissue, tendons, aponeuroses, and most ligaments, and occur in the matrix of cartilage and osseous tissue. Synonym: white fibre. (05 Mar 2000) |
| collagen fibrils | The fibril's that comprise a collagen fibre, ranging from 20 to 200 nm and averaging about 100 nm in diameter (substantially larger in tendons), with cross-striations averaging 64 nm. Synonym: collagen fibrils. (05 Mar 2000) |
| collagen injection | Correction of superficial soft tissue deformities, acne scars, or age-related skin changes by injection (implantation) of collagen; bovine collagen preparations are commonly used. Prior intradermal testing is necessary to exclude hypersensitivity. (05 Mar 2000) |
| collagen telopeptidase | <enzyme> Neutral metalloproteinase from porcine gingiva; removes the extra-helical extension peptides proximal to the lysyl residue at position 17 Registry number: EC 3.4.24.- Synonym: collagen depolymerase (26 Jun 1999) |
| collagen-vascular diseases | A group of generalised disease's affecting connective tissue and frequently characterised by fibrinoid necrosis or vasculitis; in some collagen disease's, auto-immunization, particularly antinuclear antibodies, has been shown and circulating immune complexes are found. The term is not entirely acceptable because there is no evidence that collagen is primarily involved; "collagen" was once synonymous with "connective tissue" rather than describing a specific fibrinous protein in that tissue. See: connective-tissue diseases. (05 Mar 2000) |
| SLS collagen | <protein> Abnormal packing pattern of collagen molecules formed if ATP is added to acidic collagen solutions, in which lateral aggregates of molecules are produced. Each aggregate is 300 nm long and the molecules are all in register. If SLS aggregates are overlapped with a quarter stagger, the 67 nm banding pattern of normal fibrils is reconstituted. (19 Jan 1998) |
| type I collagen | The most abundant collagen, which forms large well-organised fibrils having high tensile strength. (05 Mar 2000) |
| type II collagen | Collagen unique to cartilage, nucleus pulposis, notochord, and vitreous body; it forms as thin highly glycosylated fibrils. (05 Mar 2000) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|