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| CMP | cardiomyopathy; cartilage matrix protein; chondromalacia patellae; collagen binding protein; competi... |
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| col | collection; colicin; collagen; colony; colored; column; strain [Lat. cola] |
| CSC | blow on blow (administration of small amounts of drugs at short intervals) [Fr. coup sur coup]; coll... |
| CVD | cardiovascular disease; cerebrovascular disease; collagen vascular disease; color-vision-deviant |
| FACIT | fibril-associated collagen with interrupted triple helices |
| BCE | Bone collagen equivalent |
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| COL | Collagen |
| GAG | Collagen and glycosaminoglycan |
| CIA | Collagen induced arthritis |
| CII | Collagen type II |
| Mallory's collagen stain | <technique> One of a number of staining methods using phosphomolybdic or phosphotungstic acid with an acid stain, such as aniline blue, or with haematoxylin for connective tissue staining. (05 Mar 2000) |
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| collagen | <protein> The protein substance of the white fibres (collagenous fibres) of skin, tendon, bone, cartilage and all other connective tissue, composed of molecules of tropocollagen, it is converted into gelatin by boiling. Collagenous pertaining to collagen, forming or producing collagen. Origin: Gr. Kolla = glue, gennan = to produce (18 Nov 1997) |
| collagen diseases | Historically, a heterogeneous group of acute and chronic diseases, including rheumatoid arthritis, systemic lupus erythematosus, progressive systemic sclerosis, dermatomyositis, etc. This classification was based on the notion that "collagen" was equivalent to "connective tissue", but with the present recognition of the different types of collagen and the aggregates derived from them as distinct entities, the term "collagen diseases" now pertains exclusively to those inherited conditions in which the primary defect is at the gene level and affects collagen biosynthesis, post-translational modification, or extracellular processing directly. (12 Dec 1998) |
| collagen fibre | An individual fibre that varies in diameter from less than 1 um to about 12 um and is composed of fibrils; the fibre's, which are usually arranged in bundles, undergo some branching and are of indefinite length; chemically the fibre is a glycoprotein, collagen, which yields gelatin upon boiling; they make up the principal element of irregular connective tissue, tendons, aponeuroses, and most ligaments, and occur in the matrix of cartilage and osseous tissue. Synonym: white fibre. (05 Mar 2000) |
| collagen fibrils | The fibril's that comprise a collagen fibre, ranging from 20 to 200 nm and averaging about 100 nm in diameter (substantially larger in tendons), with cross-striations averaging 64 nm. Synonym: collagen fibrils. (05 Mar 2000) |
| collagen injection | Correction of superficial soft tissue deformities, acne scars, or age-related skin changes by injection (implantation) of collagen; bovine collagen preparations are commonly used. Prior intradermal testing is necessary to exclude hypersensitivity. (05 Mar 2000) |
| collagen telopeptidase | <enzyme> Neutral metalloproteinase from porcine gingiva; removes the extra-helical extension peptides proximal to the lysyl residue at position 17 Registry number: EC 3.4.24.- Synonym: collagen depolymerase (26 Jun 1999) |
| collagen-vascular diseases | A group of generalised disease's affecting connective tissue and frequently characterised by fibrinoid necrosis or vasculitis; in some collagen disease's, auto-immunization, particularly antinuclear antibodies, has been shown and circulating immune complexes are found. The term is not entirely acceptable because there is no evidence that collagen is primarily involved; "collagen" was once synonymous with "connective tissue" rather than describing a specific fibrinous protein in that tissue. See: connective-tissue diseases. (05 Mar 2000) |
| SLS collagen | <protein> Abnormal packing pattern of collagen molecules formed if ATP is added to acidic collagen solutions, in which lateral aggregates of molecules are produced. Each aggregate is 300 nm long and the molecules are all in register. If SLS aggregates are overlapped with a quarter stagger, the 67 nm banding pattern of normal fibrils is reconstituted. (19 Jan 1998) |
| type I collagen | The most abundant collagen, which forms large well-organised fibrils having high tensile strength. (05 Mar 2000) |
| type II collagen | Collagen unique to cartilage, nucleus pulposis, notochord, and vitreous body; it forms as thin highly glycosylated fibrils. (05 Mar 2000) |
| type III collagen | Collagen characteristic of reticular fibres. (05 Mar 2000) |
| type IV collagen | A less distinctly fibrillar form of collagen characteristic of basement membranes. (05 Mar 2000) |
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