| 영문 | cobalamin | 한글 | 코발라민 |
|---|---|---|---|
| 설명 | 비타민 B12의 다른 이름. 비타민 B12는 유전정보를 가지고 있는 DNA의 합성에 반드시 필요한 영양소로 핵분열에 없어서는 안되는 중요한 영양소이다. 이 영양소가 결핍이 될 경우엔 거대적모구빈혈(megaloblastic anemia)라는 특징적인 빈혈이 생긴다. 이 빈혈은 핵분열에 중요한 물질인 코발라민이 결핍될 경우에 적혈구를 생산하는 세포의 분열이 일어나지 않아서 생기는 것으로 특징적으로 현미경으로 관찰할 시에 적혈구의 크기가 아주 크고 중간에 맑게 보이는 부분이 아주 작다. 비타민 B12의 흡수는 위에서 위산과 함께 분비되는 내인인자(intrinsic factor)라는 물질과 함께 결합하여 장에 와서 흡수가 된다. 만일 위에서 내인인자가 분비되지 않는다면 Vit B12는 흡수가 될 수 없어서 체내에 Vit B12의 결핍을 초래하게 된다. 이로 인해서 거대적모구빈혈가 생길 수 있다. 이렇게 위에서 내인인자의 분비 장애에 의해서 일어난 빈혈을 악성빈혈이라 한다. |
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| Cbl | cobalamin |
|---|---|
| CBP | calcium-binding protein; carbohydrate-binding protein; cardiopulmonary bypass; chlorobiphenyl; cobal... |
| DHFR | DiHydroFolate Reductase |
| ADR | activation, depression, repetition [in bone remodeling]; adrenodoxin reductase; Adriamycin; adverse ... |
| ALDR | aldose reductase |
| Cbl | Cobalamin |
|---|---|
| Me-Cbl | Methyl-cobalamin |
| HMG-CoA reductase | 3-Hydroxy-3-methylglutaryl CoA reductase |
| HMG-CoA reductase | 3-Hydroxy-3-methylglutaryl coenzyme A reductase |
| MTHFR | 10-Methylenetetrahydrofolate reductase |
| ATP cobalamin adenoxyltransferase | <enzyme> An enzyme that catalyses the reaction of ATP, water, and cobalamin to form orthophosphate, pyrophosphate, and adenoxylcobalamin. Adenosylcobalamin is required by methylmalonyl-CoA mutase. A deficiency of ATP cobalamin adenosyltransferase will lead to methylmalonic acidemia. (05 Mar 2000) |
|---|---|
| cobalamin | <biochemistry> Member of the water soluble B vitamin group, important in the proper function of the nervous system and important in proper carbohydrate, protein and fat metabolism. (27 Sep 1997) |
| cobalamin (5'-phosphate)synthase | <enzyme> From pseudomonas denitrificans; catalyses the synthesis of cobalamin 5'-phosphate from GDP-cobinamide and alpha-ribazole 5'-phosphate, but also the synthesis of cobalamin from GDP-cobinamide and alpha-ribazole Registry number: EC 2.6.99.- Synonym: cobv gene product (26 Jun 1999) |
| cobalamin concentrate | The dried, partially purified product resulting from the growth of selected Streptomyces cultures or other cobalamin-producing microorganisms; contains at least 500 ug of cobalamin in each gram. (05 Mar 2000) |
| acetoacetyl-CoA reductase | An oxidoreductase catalyzing interconversion of a 3-oxoacyl-CoA and NADPH, and the corresponding d-3-hydroxyacyl-CoA, and NADP+. A step in fatty acid synthesis. (05 Mar 2000) |
| acetohexamide reductase | <enzyme> Catalyses the conversion of acetohexamide to (-)-hydroxyhexamide Registry number: EC 1.1.1.- (26 Jun 1999) |
| acryloyl-CoA reductase | <enzyme> Clostridium kluyveri enzyme; contains fmn, ferredoxin, and flavodoxin; can act as electron donors Registry number: EC 1.3.99.- Synonym: acryloyo-coenzyme a reductase (26 Jun 1999) |
| aflatoxin B1 aldehyde reductase | <enzyme> Catalyses the conversion of the dialdehydic form of aflatoxin b1-dihydrodiol to the dialcohol form Registry number: EC 1.1.1.- Synonym: aflatoxin b1-aldehyde reductase, afb1-ar (26 Jun 1999) |
| aflatoxin B1 reductase | <enzyme> Reduces the cyclopentenone ring of aflatoxin b1 to aflatoxicol; requires NADPH as cofactor Registry number: EC 1.1.1.- (26 Jun 1999) |
| aflatoxin G2a reductase | <enzyme> Has broad substrate specificity in cell-free extracts from aspergillus parasiticus; versicolorin a hemiacetal is reduced to versicolorin c; 17-hydroxy-16,17-dihydrosterigmatocystin is reduced to a 14,17-hydrated derivative; aflatoxin g2a is converted to a 13,16-hydrated derivative of afg2 Registry number: EC 1.1.1.- (26 Jun 1999) |
| aldehyde reductase | <enzyme> An enzyme that catalyses reversibly the oxidation of an aldose to an alditol. It possesses broad specificity for many aldoses. Chemical name: Alditol:NAD(P)+ 1-oxidoreductase Registry number: EC 1.1.1.21 (12 Dec 1998) |
| aldose reductase | A polyol dehydrogenase (NADP+);an oxidoreductase that reversibly converts aldoses to alditols (e.g., glucose to sorbitol) with NADPH as hydrogen donor. An important step in the metabolism of sorbitol and in the formation of diabetic cataracts. See: d-sorbitol-6-phosphate dehydrogenase. (05 Mar 2000) |
| aldose reductase inhibitor | <pharmacology> A class of drugs being studied as a way to prevent eye and nerve damage in people with diabetes. Aldose reductase is an enzyme that is normally present in the eye and in many other parts of the body. It helps change glucose (sugar) into a sugar alcohol called sorbitol. Too much sorbitol trapped in eye and nerve cells can damage these cells, leading to retinopathy and neuropathy. Drugs that prevent or slow (inhibit) the action of aldose reductase are being studied as a way to prevent or delay these complications of diabetes. (09 Oct 1997) |
| alkyl hydroperoxide reductase | <enzyme> Reduces an alkyl hydroperoxide to the corresponding alcohol in the presence of NADPH; ahpc gene product from salmonella typhimurium Registry number: EC 1.- Synonym: ahpc gene product, alkylhydroperoxide reductase, ahpf gene product (26 Jun 1999) |
| alpha,beta-ketoalkene reductase | <enzyme> Nadh is much less effective than NADPH; catalyses the reduction of the carbon-carbon double bond of five membered ring cpds which have two conjugated carbonyl groups on both sides of a double bond Registry number: EC 1.3.1.- Synonym: n-ethylmaleimide reducing enzyme, NADPH-linked alpha,beta-ketoalkene double bond reductase, n-ethylmaleimide reductase (26 Jun 1999) |
| cobalamin reductase |
either of two mitochondrial reductases that catalyze steps in the synthesis of adenosylcobalamin from hydroxocobalamin; deficiency of one or both is believed to be a cause of methylmalonicacidemia (q.v.).
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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