| ¿µ¹® | cobalamin | ÇÑ±Û | Äڹ߶ó¹Î |
|---|---|---|---|
| ¼³¸í | ºñŸ¹Î B12ÀÇ ´Ù¸¥ À̸§. ºñŸ¹Î B12´Â À¯ÀüÁ¤º¸¸¦ °¡Áö°í ÀÖ´Â DNAÀÇ ÇÕ¼º¿¡ ¹Ýµå½Ã ÇÊ¿äÇÑ ¿µ¾ç¼Ò·Î Çٺп¿¡ ¾ø¾î¼´Â ¾ÈµÇ´Â Áß¿äÇÑ ¿µ¾ç¼ÒÀÌ´Ù. ÀÌ ¿µ¾ç¼Ò°¡ °áÇÌÀÌ µÉ °æ¿ì¿£ °Å´ëÀû¸ð±¸ºóÇ÷(megaloblastic anemia)¶ó´Â Ư¡ÀûÀÎ ºóÇ÷ÀÌ »ý±ä´Ù. ÀÌ ºóÇ÷Àº Çٺп¿¡ Áß¿äÇÑ ¹°ÁúÀÎ Äڹ߶ó¹ÎÀÌ °áÇÌµÉ °æ¿ì¿¡ ÀûÇ÷±¸¸¦ »ý»êÇÏ´Â ¼¼Æ÷ÀÇ ºÐ¿ÀÌ ÀϾÁö ¾Ê¾Æ¼ »ý±â´Â °ÍÀ¸·Î Ư¡ÀûÀ¸·Î Çö¹Ì°æÀ¸·Î °üÂûÇÒ ½Ã¿¡ ÀûÇ÷±¸ÀÇ Å©±â°¡ ¾ÆÁÖ Å©°í Áß°£¿¡ ¸¼°Ô º¸ÀÌ´Â ºÎºÐÀÌ ¾ÆÁÖ ÀÛ´Ù. ºñŸ¹Î B12ÀÇ Èí¼ö´Â À§¿¡¼ À§»ê°ú ÇÔ²² ºÐºñµÇ´Â ³»ÀÎÀÎÀÚ(intrinsic factor)¶ó´Â ¹°Áú°ú ÇÔ²² °áÇÕÇÏ¿© Àå¿¡ ¿Í¼ Èí¼ö°¡ µÈ´Ù. ¸¸ÀÏ À§¿¡¼ ³»ÀÎÀÎÀÚ°¡ ºÐºñµÇÁö ¾Ê´Â´Ù¸é Vit B12´Â Èí¼ö°¡ µÉ ¼ö ¾ø¾î¼ ü³»¿¡ Vit B12ÀÇ °áÇÌÀ» ÃÊ·¡ÇÏ°Ô µÈ´Ù. ÀÌ·Î ÀÎÇØ¼ °Å´ëÀû¸ð±¸ºóÇ÷°¡ »ý±æ ¼ö ÀÖ´Ù. ÀÌ·¸°Ô À§¿¡¼ ³»ÀÎÀÎÀÚÀÇ ºÐºñ Àå¾Ö¿¡ ÀÇÇØ¼ ÀÏ¾î³ ºóÇ÷À» ¾Ç¼ººóÇ÷À̶ó ÇÑ´Ù. |
||
| Cbl | cobalamin |
|---|---|
| CBP | calcium-binding protein; carbohydrate-binding protein; cardiopulmonary bypass; chlorobiphenyl; cobal... |
| Cbl | Cobalamin |
|---|---|
| Me-Cbl | Methyl-cobalamin |
| cobalamin (5'-phosphate)synthase | <enzyme> From pseudomonas denitrificans; catalyses the synthesis of cobalamin 5'-phosphate from GDP-cobinamide and alpha-ribazole 5'-phosphate, but also the synthesis of cobalamin from GDP-cobinamide and alpha-ribazole Registry number: EC 2.6.99.- Synonym: cobv gene product (26 Jun 1999) |
|---|
| ATP cobalamin adenoxyltransferase | <enzyme> An enzyme that catalyses the reaction of ATP, water, and cobalamin to form orthophosphate, pyrophosphate, and adenoxylcobalamin. Adenosylcobalamin is required by methylmalonyl-CoA mutase. A deficiency of ATP cobalamin adenosyltransferase will lead to methylmalonic acidemia. (05 Mar 2000) |
|---|---|
| cobalamin | <biochemistry> Member of the water soluble B vitamin group, important in the proper function of the nervous system and important in proper carbohydrate, protein and fat metabolism. (27 Sep 1997) |
| cobalamin concentrate | The dried, partially purified product resulting from the growth of selected Streptomyces cultures or other cobalamin-producing microorganisms; contains at least 500 ug of cobalamin in each gram. (05 Mar 2000) |
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