| del | deletion; delivery; delusion |
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| D | Deletion |
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| I/D | Insertion-deletion |
| D-I | deletion-insertion |
| clonal deletion | The removal of B-cell and T-cell varieties which recognise parts of the organisms body as targets of the immune system. This process naturally occurs early in the organisms development so that the organism will not be autoimmune (having an immune reaction against one's own body tissues) later in life. (09 Oct 1997) |
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| clonal deletion theory | The elimination of certain T-cell populations in the thymus that have receptors for self-antigens. See: immunologic tolerance. (05 Mar 2000) |
| clonal | Pertaining to a clone. (05 Mar 2000) |
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| clonal aging | The deterioration in successive generations of a clone; thus paramecia and other simple forms, if allowed to reproduce asexually for a number of generations, invariably undergo deterioration, the characters of each group of descendants progressively departing from those of the original sexually produced ancestor. (05 Mar 2000) |
| clonal anergy | Functional inactivation of t- or B-lymphocytes rendering them incapable of eliciting an immune response to antigen. This occurs through different mechanisms in the two kinds of lymphocytes and can contribute to self tolerance. (12 Dec 1998) |
| clonal expansion | Production of daughter cells all arising originally from a single cell. (05 Mar 2000) |
| clonal selection | <cell biology> The process whereby one or more clones, i.e. Cells expressing a particular gene sequence are selected by naturally occurring processes from a mixed population. Generally the clonal selection is for general expansion by mitosis, particularly with reference to B lymphocytes where selection with subsequent expansion of clones occurs as a result of antigenic stimulation only of those lymphocytes bearing the appropriate receptors. (18 Nov 1997) |
| clonal selection theory | A theory which states that each lymphocyte has membrane bound immunoglobulin receptors specific for a particular antigen and once the receptor is engaged, proliferation of the cell occurs such that a clone of antibody producing cells (plasma cell) is produced. (05 Mar 2000) |
| addition-deletion mutation | <molecular biology> A type of mutation that results from insertion or deletion of a single nucleotide into, or from, an open reading frame in the normal DNA sequence. Normally, the genetic code is read in the wrong frame, three nucleotides at a time, and the entire sequence downstream of the mutation, is translated into a polypeptide with a garbled amino acid sequence from the mutated codon onwards. These mutations may be induced by certain types of mutagens or may occur spontaneously and usually result in the generation, downstream, of nonsense, chain termination codons. Synonym: addition mutation, addition-deletion mutation, deletion mutation, reading-frameshift mutation. (21 Jun 2000) |
| gene deletion | The total loss (or absence) of a gene. Gene deletion plays a role in birth defects and in the development of cancer. (12 Dec 1998) |
| chromosomal deletion | A microscopically evident loss of part of a chromosome. See: monosomy. (05 Mar 2000) |
| chromosome deletion | Actual loss of a portion of the chromosome. (12 Dec 1998) |
| point deletion | Deletion involving a submicroscopic loss of genetic material too small to be resolved by linkage analysis. Synonym: nucleotide deletion. (05 Mar 2000) |
| sequence deletion | Deletion of sequences of bases or amino acids from the genetic material of an individual. Evidence for these deletions may be obtained by cytological methods. (12 Dec 1998) |
| nucleotide deletion | Deletion of a single nucleotide, which in a transcribed gene will lead to a frameshift mutation. Synonym: point deletion. (05 Mar 2000) |
| deletion | <genetics> A chromosome abnormality in which part of a single chromosome has been lost. (13 Nov 1997) |
| deletion mutation | <molecular biology> A mutation in which one or more (sequential) nucleotides is lost by the genome. If the number lost is not divisible by 3 and is in a coding region, the result is a frameshift mutation. (18 Nov 1997) |
Synonyms : Abortion, Clonal, Abortions, Clonal, Clonal Abortions, Clonal Deletions, Deletion, Clonal, Deletions, Clonal
| clonal deletion t. |
a theory of immunologic tolerance to self antigens according to which “forbidden clones” of immunocytes, those reactive with self antigens, are eliminated on contact with antigen during fetal life. The terms “clonal abortion,” “clonal anergy,” “clonal silencing,” and “clonal purging” have also been used for this phenomenon. See also clonal selection t.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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