| NYHA | New York Heart Association Heart Disease¿¡ ´ëÇÑ Functional Classification &nbs... |
|---|---|
| MHC | Major Histocompatibility Complex |
| C/MHC | community/migrant health center |
| MHC | major histocompatibility complex; mental health care |
| BGC | basal ganglion calcification; blood group class |
| MHC II | MHC Class II |
|---|---|
| MHC I | MHC class I |
| MHC | Major histocompatibility antigens |
| MHC-II | Major Histocompatibility Complex class II |
| MHC-I | Major histocompatibility complex class I |
| genes, MHC class I | Genetic loci in the vertebrate major histocompatibility complex which encode polymorphic characteristics not related to immune responsiveness or complement activity, e.g., b loci (chicken), dla (dog), gpla (guinea pig), h-2 (mouse), rt-1 (rat), HLA-a, -b, and -c class I genes of man. (12 Dec 1998) |
|---|---|
| genes, MHC class II | Genetic loci in the vertebrate major histocompatibility complex that encode polymorphic products which control the immune response to specific antigens. The genes are found in the HLA-d region in humans and in the I region in mice. (12 Dec 1998) |
| MHC class II protein | <protein> The antigen-presenting molecule found primarily on macrophages and B lymphocytes. (09 Oct 1997) |
| MHC class I protein | <protein> The antigen-presenting molecule found on all nucleated vertebrate cells. (09 Oct 1997) |
| class I antigens | Cell membrane bound glycoproteins that are coded by genes of the major histocompatibility complex. (05 Mar 2000) |
| class II antigens | A cell membrane glycoprotein encoded by genes of the major histocompatibility complex. These antigens are distributed on antigen-presenting cells such as macrophages, B-cells, and dendritic cells. (05 Mar 2000) |
| class III antigens | Non-cell membrane molecules that are encoded by the S region of the major histocompatibility complex. These antigens are not involved in determining histocompatibility and include the complement proteins. (05 Mar 2000) |
| histocompatibility antigens class I | Large transmembrane, polymorphic glycoproteins noncovalently associated with nonpolymorphic beta 2-microglobulin. In humans, three structural genes on chromosome 6 code for the HLA-a, HLA-b and HLA-c antigens. In mice, three genes named k, d, and l on chromosome 17 code for the h-2 antigens. Class I antigens are found on most nucleated cells and are generally detected by their reactivity with alloantisera. These antigens are recognised during graft rejection and restrict cell-mediated lysis of virus-infected cells. They are primarily associated with rheumatologic diseases and certain malignant disorders. (12 Dec 1998) |
| histocompatibility antigens class II | Large, transmembrane, non-covalently linked glycoproteins (alpha and beta). Both chains can be polymorphic although there is more structural variation in the beta chains. The class II antigens in humans are called HLA-d antigens and are coded by a gene on chromosome 6. In mice, two genes named ia and i.e. On chromosome 17 code for the h-2 antigens. The antigens are found on B-lymphocytes, macrophages, epidermal cells, and sperm and are thought to mediate the competence of and cellular cooperation in the immune response. The term ia antigens used to refer only to the proteins encoded by the ia genes in the mouse, but is now used as a generic term for any class II histocompatibility antigen. (12 Dec 1998) |
| MHC | The set of gene loci specifying major histocompatibility antigens, for example HLA in man, H 2 in mice, RLA in rabbits, RT 1 in rats, DLA in dogs, SLA in pigs, etc. Acronym: MHC (18 Nov 1997) |
| MHC restriction | <immunology> Restriction on interaction between cells of the immune system because of the requirement to recognise foreign antigen is association with MHC antigens (major histocompatibility antigens). Thus, cytotoxic T-cells will only kill virally infected cells that have the same Class I antigens as themselves, whereas helper T-cells respond to foreign antigen associated with Class II antigens. (18 Nov 1997) |
| age-class | <ecology> A group of individuals of a species that have the same age. (09 Oct 1997) |
| malocclusion, angle class I | Malocclusion in which the mandible and maxilla are anteroposteriorly normal as reflected by the relationship of the first permanent molar (i.e., in neutroclusion), but in which individual teeth are abnormally related to each other. (12 Dec 1998) |
| malocclusion, angle class II | Malocclusion in which the mandible is posterior to the maxilla as reflected by the relationship of the first permanent molar (distoclusion). (12 Dec 1998) |
| malocclusion, angle class III | Malocclusion in which the mandible is anterior to the maxilla as reflected by the first relationship of the first permanent molar (mesioclusion). (12 Dec 1998) |
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